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Items: 1 to 20 of 108


A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable.

Tian H, Biehs B, Warming S, Leong KG, Rangell L, Klein OD, de Sauvage FJ.

Nature. 2011 Sep 18;478(7368):255-9. doi: 10.1038/nature10408. Erratum in: Nature. 2012 Feb 2;482(7383):120.


Dynamic coordination of innate immune signaling and insulin signaling regulates systemic responses to localized DNA damage.

Karpac J, Younger A, Jasper H.

Dev Cell. 2011 Jun 14;20(6):841-54. doi: 10.1016/j.devcel.2011.05.011.


Strategies for homeostatic stem cell self-renewal in adult tissues.

Simons BD, Clevers H.

Cell. 2011 Jun 10;145(6):851-62. doi: 10.1016/j.cell.2011.05.033. Review.


Epithelial progenitor cells in lung development, maintenance, repair, and disease.

Rock JR, Hogan BL.

Annu Rev Cell Dev Biol. 2011;27:493-512. doi: 10.1146/annurev-cellbio-100109-104040. Epub 2011 May 31. Review.


Notch-dependent differentiation of adult airway basal stem cells.

Rock JR, Gao X, Xue Y, Randell SH, Kong YY, Hogan BL.

Cell Stem Cell. 2011 Jun 3;8(6):639-48. doi: 10.1016/j.stem.2011.04.003.


Tuberous sclerosis complex and Myc coordinate the growth and division of Drosophila intestinal stem cells.

Amcheslavsky A, Ito N, Jiang J, Ip YT.

J Cell Biol. 2011 May 16;193(4):695-710. doi: 10.1083/jcb.201103018. Epub 2011 May 9.


Defining the origins of Ras/p53-mediated squamous cell carcinoma.

White AC, Tran K, Khuu J, Dang C, Cui Y, Binder SW, Lowry WE.

Proc Natl Acad Sci U S A. 2011 May 3;108(18):7425-30. doi: 10.1073/pnas.1012670108. Epub 2011 Apr 18.


Identifying the cellular origin of squamous skin tumors.

Lapouge G, Youssef KK, Vokaer B, Achouri Y, Michaux C, Sotiropoulou PA, Blanpain C.

Proc Natl Acad Sci U S A. 2011 May 3;108(18):7431-6. doi: 10.1073/pnas.1012720108. Epub 2011 Apr 18.


EGFR, Wingless and JAK/STAT signaling cooperatively maintain Drosophila intestinal stem cells.

Xu N, Wang SQ, Tan D, Gao Y, Lin G, Xi R.

Dev Biol. 2011 Jun 1;354(1):31-43. doi: 10.1016/j.ydbio.2011.03.018. Epub 2011 Apr 1.


Experimental inflammatory bowel disease: insights into the host-microbiota dialog.

Saleh M, Elson CO.

Immunity. 2011 Mar 25;34(3):293-302. doi: 10.1016/j.immuni.2011.03.008. Review.


The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse.

Merlos-Suárez A, Barriga FM, Jung P, Iglesias M, Céspedes MV, Rossell D, Sevillano M, Hernando-Momblona X, da Silva-Diz V, Muñoz P, Clevers H, Sancho E, Mangues R, Batlle E.

Cell Stem Cell. 2011 May 6;8(5):511-24. doi: 10.1016/j.stem.2011.02.020. Epub 2011 Mar 17.


EGF signaling regulates the proliferation of intestinal stem cells in Drosophila.

Biteau B, Jasper H.

Development. 2011 Mar;138(6):1045-55. doi: 10.1242/dev.056671. Epub 2011 Feb 9.


Redox regulation by Keap1 and Nrf2 controls intestinal stem cell proliferation in Drosophila.

Hochmuth CE, Biteau B, Bohmann D, Jasper H.

Cell Stem Cell. 2011 Feb 4;8(2):188-99. doi: 10.1016/j.stem.2010.12.006.


Proliferative neural stem cells have high endogenous ROS levels that regulate self-renewal and neurogenesis in a PI3K/Akt-dependant manner.

Le Belle JE, Orozco NM, Paucar AA, Saxe JP, Mottahedeh J, Pyle AD, Wu H, Kornblum HI.

Cell Stem Cell. 2011 Jan 7;8(1):59-71. doi: 10.1016/j.stem.2010.11.028.


Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection.

Buchon N, Broderick NA, Kuraishi T, Lemaitre B.

BMC Biol. 2010 Dec 22;8:152. doi: 10.1186/1741-7007-8-152.


EGFR/Ras/MAPK signaling mediates adult midgut epithelial homeostasis and regeneration in Drosophila.

Jiang H, Grenley MO, Bravo MJ, Blumhagen RZ, Edgar BA.

Cell Stem Cell. 2011 Jan 7;8(1):84-95. doi: 10.1016/j.stem.2010.11.026. Epub 2010 Dec 16.


Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts.

Sato T, van Es JH, Snippert HJ, Stange DE, Vries RG, van den Born M, Barker N, Shroyer NF, van de Wetering M, Clevers H.

Nature. 2011 Jan 20;469(7330):415-8. doi: 10.1038/nature09637. Epub 2010 Nov 28.


Asymmetric cell division: recent developments and their implications for tumour biology.

Knoblich JA.

Nat Rev Mol Cell Biol. 2010 Dec;11(12):849-60. doi: 10.1038/nrm3010. Review.


The Hippo tumor suppressor pathway regulates intestinal stem cell regeneration.

Karpowicz P, Perez J, Perrimon N.

Development. 2010 Dec;137(24):4135-45. doi: 10.1242/dev.060483.


Hippo signaling regulates Drosophila intestine stem cell proliferation through multiple pathways.

Ren F, Wang B, Yue T, Yun EY, Ip YT, Jiang J.

Proc Natl Acad Sci U S A. 2010 Dec 7;107(49):21064-9. doi: 10.1073/pnas.1012759107. Epub 2010 Nov 15.

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