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Items: 1 to 20 of 47


Reinforcement-related regulation of AMPA glutamate receptor subunits in the ventral tegmental area enhances motivation for cocaine.

Choi KH, Edwards S, Graham DL, Larson EB, Whisler KN, Simmons D, Friedman AK, Walsh JJ, Rahman Z, Monteggia LM, Eisch AJ, Neve RL, Nestler EJ, Han MH, Self DW.

J Neurosci. 2011 May 25;31(21):7927-37. doi: 10.1523/JNEUROSCI.6014-10.2011.


Epigenetic modification of hippocampal Bdnf DNA in adult rats in an animal model of post-traumatic stress disorder.

Roth TL, Zoladz PR, Sweatt JD, Diamond DM.

J Psychiatr Res. 2011 Jul;45(7):919-26. doi: 10.1016/j.jpsychires.2011.01.013.


The epigenetic landscape of addiction.

Maze I, Nestler EJ.

Ann N Y Acad Sci. 2011 Jan;1216:99-113. doi: 10.1111/j.1749-6632.2010.05893.x. Review.


Cocaine-induced chromatin remodeling increases brain-derived neurotrophic factor transcription in the rat medial prefrontal cortex, which alters the reinforcing efficacy of cocaine.

Sadri-Vakili G, Kumaresan V, Schmidt HD, Famous KR, Chawla P, Vassoler FM, Overland RP, Xia E, Bass CE, Terwilliger EF, Pierce RC, Cha JH.

J Neurosci. 2010 Sep 1;30(35):11735-44. doi: 10.1523/JNEUROSCI.2328-10.2010.


Role of BDNF and GDNF in drug reward and relapse: a review.

Ghitza UE, Zhai H, Wu P, Airavaara M, Shaham Y, Lu L.

Neurosci Biobehav Rev. 2010 Nov;35(2):157-71. doi: 10.1016/j.neubiorev.2009.11.009. Review.


New insights in the biology of BDNF synthesis and release: implications in CNS function.

Greenberg ME, Xu B, Lu B, Hempstead BL.

J Neurosci. 2009 Oct 14;29(41):12764-7. doi: 10.1523/JNEUROSCI.3566-09.2009. Review.


Brain-derived neurotrophic factor and cocaine addiction.

McGinty JF, Whitfield TW Jr, Berglind WJ.

Brain Res. 2010 Feb 16;1314:183-93. doi: 10.1016/j.brainres.2009.08.078. Review.


A single intra-PFC infusion of BDNF prevents cocaine-induced alterations in extracellular glutamate within the nucleus accumbens.

Berglind WJ, Whitfield TW Jr, LaLumiere RT, Kalivas PW, McGinty JF.

J Neurosci. 2009 Mar 25;29(12):3715-9. doi: 10.1523/JNEUROSCI.5457-08.2009.


Epigenetic regulation of BDNF gene transcription in the consolidation of fear memory.

Lubin FD, Roth TL, Sweatt JD.

J Neurosci. 2008 Oct 15;28(42):10576-86. doi: 10.1523/JNEUROSCI.1786-08.2008.


Histone deacetylase inhibitors decrease cocaine but not sucrose self-administration in rats.

Romieu P, Host L, Gobaille S, Sandner G, Aunis D, Zwiller J.

J Neurosci. 2008 Sep 17;28(38):9342-8. doi: 10.1523/JNEUROSCI.0379-08.2008.


Chromatin-modifying enzymes as therapeutic targets--Part 1.

Keppler BR, Archer TK.

Expert Opin Ther Targets. 2008 Oct;12(10):1301-12. doi: 10.1517/14728222.12.10.1301 . Review.


Epigenetic mechanisms in drug addiction.

Renthal W, Nestler EJ.

Trends Mol Med. 2008 Aug;14(8):341-50. doi: 10.1016/j.molmed.2008.06.004. Review.


Fetal alcohol spectrum disorder-associated depression: evidence for reductions in the levels of brain-derived neurotrophic factor in a mouse model.

Caldwell KK, Sheema S, Paz RD, Samudio-Ruiz SL, Laughlin MH, Spence NE, Roehlk MJ, Alcon SN, Allan AM.

Pharmacol Biochem Behav. 2008 Oct;90(4):614-24. doi: 10.1016/j.pbb.2008.05.004.


Neuroplasticity in the mesolimbic dopamine system and cocaine addiction.

Thomas MJ, Kalivas PW, Shaham Y.

Br J Pharmacol. 2008 May;154(2):327-42. doi: 10.1038/bjp.2008.77. Review.


Drug-induced activation of dopamine D(1) receptor signaling and inhibition of class I/II histone deacetylase induce chromatin remodeling in reward circuitry and modulate cocaine-related behaviors.

Schroeder FA, Penta KL, Matevossian A, Jones SR, Konradi C, Tapper AR, Akbarian S.

Neuropsychopharmacology. 2008 Nov;33(12):2981-92. doi: 10.1038/npp.2008.15.


BHLHB2 controls Bdnf promoter 4 activity and neuronal excitability.

Jiang X, Tian F, Du Y, Copeland NG, Jenkins NA, Tessarollo L, Wu X, Pan H, Hu XZ, Xu K, Kenney H, Egan SE, Turley H, Harris AL, Marini AM, Lipsky RH.

J Neurosci. 2008 Jan 30;28(5):1118-30. doi: 10.1523/JNEUROSCI.2262-07.2008.


Repeated exposure to cocaine differently modulates BDNF mRNA and protein levels in rat striatum and prefrontal cortex.

Fumagalli F, Di Pasquale L, Caffino L, Racagni G, Riva MA.

Eur J Neurosci. 2007 Nov;26(10):2756-63.


Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli.

Renthal W, Maze I, Krishnan V, Covington HE 3rd, Xiao G, Kumar A, Russo SJ, Graham A, Tsankova N, Kippin TE, Kerstetter KA, Neve RL, Haggarty SJ, McKinsey TA, Bassel-Duby R, Olson EN, Nestler EJ.

Neuron. 2007 Nov 8;56(3):517-29.


Persistent alterations in mesolimbic gene expression with abstinence from cocaine self-administration.

Freeman WM, Patel KM, Brucklacher RM, Lull ME, Erwin M, Morgan D, Roberts DC, Vrana KE.

Neuropsychopharmacology. 2008 Jul;33(8):1807-17.

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