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Items: 1 to 20 of 37

1.

Functional consequences of HLA-DQ8 homozygosity versus heterozygosity for islet autoimmunity in type 1 diabetes.

Eerligh P, van Lummel M, Zaldumbide A, Moustakas AK, Duinkerken G, Bondinas G, Koeleman BP, Papadopoulos GK, Roep BO.

Genes Immun. 2011 Sep;12(6):415-27. doi: 10.1038/gene.2011.24. Epub 2011 May 12.

PMID:
21562577
2.

Diabetogenic T cells recognize insulin bound to IAg7 in an unexpected, weakly binding register.

Stadinski BD, Zhang L, Crawford F, Marrack P, Eisenbarth GS, Kappler JW.

Proc Natl Acad Sci U S A. 2010 Jun 15;107(24):10978-83. doi: 10.1073/pnas.1006545107. Epub 2010 Jun 1.

3.

The diabetogenic mouse MHC class II molecule I-Ag7 is endowed with a switch that modulates TCR affinity.

Yoshida K, Corper AL, Herro R, Jabri B, Wilson IA, Teyton L.

J Clin Invest. 2010 May;120(5):1578-90. doi: 10.1172/JCI41502. Epub 2010 Apr 19.

4.

Unique autoreactive T cells recognize insulin peptides generated within the islets of Langerhans in autoimmune diabetes.

Mohan JF, Levisetti MG, Calderon B, Herzog JW, Petzold SJ, Unanue ER.

Nat Immunol. 2010 Apr;11(4):350-4. doi: 10.1038/ni.1850. Epub 2010 Feb 28.

5.

Chromogranin A is an autoantigen in type 1 diabetes.

Stadinski BD, Delong T, Reisdorph N, Reisdorph R, Powell RL, Armstrong M, Piganelli JD, Barbour G, Bradley B, Crawford F, Marrack P, Mahata SK, Kappler JW, Haskins K.

Nat Immunol. 2010 Mar;11(3):225-31. doi: 10.1038/ni.1844. Epub 2010 Feb 7.

6.

Regulatory T cells and inhibitory cytokines in autoimmunity.

Bettini M, Vignali DA.

Curr Opin Immunol. 2009 Dec;21(6):612-8. doi: 10.1016/j.coi.2009.09.011. Epub 2009 Oct 23. Review.

7.

In vivo enhancement of peptide display by MHC class II molecules with small molecule catalysts of peptide exchange.

Call MJ, Xing X, Cuny GD, Seth NP, Altmann DM, Fugger L, Krogsgaard M, Stein RL, Wucherpfennig KW.

J Immunol. 2009 May 15;182(10):6342-52. doi: 10.4049/jimmunol.0803464.

8.

Analysis of T cell receptor beta chains that combine with dominant conserved TRAV5D-4*04 anti-insulin B:9-23 alpha chains.

Zhang L, Jasinski JM, Kobayashi M, Davenport B, Johnson K, Davidson H, Nakayama M, Haskins K, Eisenbarth GS.

J Autoimmun. 2009 Aug;33(1):42-9. doi: 10.1016/j.jaut.2009.02.003. Epub 2009 Mar 16.

9.

Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection.

Scott-Browne JP, White J, Kappler JW, Gapin L, Marrack P.

Nature. 2009 Apr 23;458(7241):1043-6. doi: 10.1038/nature07812. Epub 2009 Mar 4.

10.

Conserved T cell receptor alpha-chain induces insulin autoantibodies.

Kobayashi M, Jasinski J, Liu E, Li M, Miao D, Zhang L, Yu L, Nakayama M, Eisenbarth GS.

Proc Natl Acad Sci U S A. 2008 Jul 22;105(29):10090-4. doi: 10.1073/pnas.0801648105. Epub 2008 Jul 14.

11.

Time trends in the incidence of type 1 diabetes in Finnish children: a cohort study.

Harjutsalo V, Sjöberg L, Tuomilehto J.

Lancet. 2008 May 24;371(9626):1777-82. doi: 10.1016/S0140-6736(08)60765-5.

PMID:
18502302
12.

IL-10 gene modified dendritic cells inhibit T helper type 1-mediated alloimmune responses and promote immunological tolerance in diabetes.

Zhu H, Qiu W, Lei P, Zhou W, Wen X, He F, Li L, Dai H, Shen G, Gong F.

Cell Mol Immunol. 2008 Feb;5(1):41-6. doi: 10.1038/cmi.2008.5.

13.

Priming and effector dependence on insulin B:9-23 peptide in NOD islet autoimmunity.

Nakayama M, Beilke JN, Jasinski JM, Kobayashi M, Miao D, Li M, Coulombe MG, Liu E, Elliott JF, Gill RG, Eisenbarth GS.

J Clin Invest. 2007 Jul;117(7):1835-43.

14.

The insulin-specific T cells of nonobese diabetic mice recognize a weak MHC-binding segment in more than one form.

Levisetti MG, Suri A, Petzold SJ, Unanue ER.

J Immunol. 2007 May 15;178(10):6051-7.

15.

Generation of T-cell receptor retrogenic mice.

Holst J, Szymczak-Workman AL, Vignali KM, Burton AR, Workman CJ, Vignali DA.

Nat Protoc. 2006;1(1):406-17.

PMID:
17406263
16.

Small organic compounds enhance antigen loading of class II major histocompatibility complex proteins by targeting the polymorphic P1 pocket.

Höpner S, Dickhaut K, Hofstätter M, Krämer H, Rückerl D, Söderhäll JA, Gupta S, Marin-Esteban V, Kühne R, Freund C, Jung G, Falk K, Rötzschke O.

J Biol Chem. 2006 Dec 15;281(50):38535-42. Epub 2006 Sep 27.

17.

Interleukin-10-secreting type 1 regulatory T cells in rodents and humans.

Roncarolo MG, Gregori S, Battaglia M, Bacchetta R, Fleischhauer K, Levings MK.

Immunol Rev. 2006 Aug;212:28-50. Review. Erratum in: Immunol Rev. 2006 Oct;213:257.

PMID:
16903904
18.

MHC class II proteins and disease: a structural perspective.

Jones EY, Fugger L, Strominger JL, Siebold C.

Nat Rev Immunol. 2006 Apr;6(4):271-82. Review.

PMID:
16557259
19.

Small molecules that enhance the catalytic efficiency of HLA-DM.

Nicholson MJ, Moradi B, Seth NP, Xing X, Cuny GD, Stein RL, Wucherpfennig KW.

J Immunol. 2006 Apr 1;176(7):4208-20.

20.

Tr1 cells: from discovery to their clinical application.

Battaglia M, Gregori S, Bacchetta R, Roncarolo MG.

Semin Immunol. 2006 Apr;18(2):120-7. Epub 2006 Feb 7. Review.

PMID:
16464609

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