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Items: 1 to 20 of 42


A critical role for the protein apoptosis repressor with caspase recruitment domain in hypoxia-induced pulmonary hypertension.

Zaiman AL, Damico R, Thoms-Chesley A, Files DC, Kesari P, Johnston L, Swaim M, Mozammel S, Myers AC, Halushka M, El-Haddad H, Shimoda LA, Peng CF, Hassoun PM, Champion HC, Kitsis RN, Crow MT.

Circulation. 2011 Dec 6;124(23):2533-42. doi: 10.1161/CIRCULATIONAHA.111.034512. Epub 2011 Nov 14.


Expression of ARC (apoptosis repressor with caspase recruitment domain), an antiapoptotic protein, is strongly prognostic in AML.

Carter BZ, Qiu YH, Zhang N, Coombes KR, Mak DH, Thomas DA, Ravandi F, Kantarjian HM, Koller E, Andreeff M, Kornblau SM.

Blood. 2011 Jan 20;117(3):780-7. doi: 10.1182/blood-2010-04-280503. Epub 2010 Nov 1.


Induction of the apoptosis inhibitor ARC by Ras in human cancers.

Wu L, Nam YJ, Kung G, Crow MT, Kitsis RN.

J Biol Chem. 2010 Jun 18;285(25):19235-45. doi: 10.1074/jbc.M110.114892. Epub 2010 Apr 14.


Bcl-2 overexpression induces a partial epithelial to mesenchymal transition and promotes squamous carcinoma cell invasion and metastasis.

Zuo J, Ishikawa T, Boutros S, Xiao Z, Humtsoe JO, Kramer RH.

Mol Cancer Res. 2010 Feb;8(2):170-82. doi: 10.1158/1541-7786.MCR-09-0354. Epub 2010 Feb 9.


IAP regulation of metastasis.

Mehrotra S, Languino LR, Raskett CM, Mercurio AM, Dohi T, Altieri DC.

Cancer Cell. 2010 Jan 19;17(1):53-64. doi: 10.1016/j.ccr.2009.11.021.


PU.1 directly regulates cdk6 gene expression, linking the cell proliferation and differentiation programs in erythroid cells.

Choe KS, Ujhelly O, Wontakal SN, Skoultchi AI.

J Biol Chem. 2010 Jan 29;285(5):3044-52. doi: 10.1074/jbc.M109.077727. Epub 2009 Dec 2.


In vivo assay for tumor cell invasion.

Hernandez L, Smirnova T, Wyckoff J, Condeelis J, Segall JE.

Methods Mol Biol. 2009;571:227-38. doi: 10.1007/978-1-60761-198-1_15.


Lessons in signaling and tumorigenesis from polyomavirus middle T antigen.

Fluck MM, Schaffhausen BS.

Microbiol Mol Biol Rev. 2009 Sep;73(3):542-63, Table of Contents. doi: 10.1128/MMBR.00009-09. Review.


Caspase-8 association with the focal adhesion complex promotes tumor cell migration and metastasis.

Barbero S, Mielgo A, Torres V, Teitz T, Shields DJ, Mikolon D, Bogyo M, BarilĂ  D, Lahti JM, Schlaepfer D, Stupack DG.

Cancer Res. 2009 May 1;69(9):3755-63. doi: 10.1158/0008-5472.CAN-08-3937. Epub 2009 Apr 21.


Resistance of human glioblastoma multiforme cells to growth factor inhibitors is overcome by blockade of inhibitor of apoptosis proteins.

Ziegler DS, Wright RD, Kesari S, Lemieux ME, Tran MA, Jain M, Zawel L, Kung AL.

J Clin Invest. 2008 Sep;118(9):3109-22. doi: 10.1172/JCI34120.


ARC (apoptosis repressor with caspase recruitment domain) is a novel marker of human colon cancer.

Mercier I, Vuolo M, Jasmin JF, Medina CM, Williams M, Mariadason JM, Qian H, Xue X, Pestell RG, Lisanti MP, Kitsis RN.

Cell Cycle. 2008 Jun 1;7(11):1640-7. Epub 2008 Mar 19.


Rapid production of retroviruses for efficient gene delivery to mammalian cells using 293T cell-based systems.

Swift S, Lorens J, Achacoso P, Nolan GP.

Curr Protoc Immunol. 2001 May;Chapter 10:Unit 10.17C. doi: 10.1002/0471142735.im1017cs31.


Inhibition of endoplasmic reticulum stress-induced apoptosis of melanoma cells by the ARC protein.

Chen LH, Jiang CC, Watts R, Thorne RF, Kiejda KA, Zhang XD, Hersey P.

Cancer Res. 2008 Feb 1;68(3):834-42. doi: 10.1158/0008-5472.CAN-07-5056.


Identification of a critical tyrosine residue in caspase 8 that promotes cell migration.

Barbero S, BarilĂ  D, Mielgo A, Stagni V, Clair K, Stupack D.

J Biol Chem. 2008 May 9;283(19):13031-4. doi: 10.1074/jbc.M800549200. Epub 2008 Jan 23.


Diagnosing and exploiting cancer's addiction to blocks in apoptosis.

Letai AG.

Nat Rev Cancer. 2008 Feb;8(2):121-32. doi: 10.1038/nrc2297. Review.


Regulation of p53 tetramerization and nuclear export by ARC.

Foo RS, Nam YJ, Ostreicher MJ, Metzl MD, Whelan RS, Peng CF, Ashton AW, Fu W, Mani K, Chin SF, Provenzano E, Ellis I, Figg N, Pinder S, Bennett MR, Caldas C, Kitsis RN.

Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20826-31. Epub 2007 Dec 17.


cDNA array analysis for prediction of hepatic metastasis of colorectal carcinoma.

Takata O, Kawamura YJ, Konishi F, Sasaki J, Kai T, Miyakura Y, Nagai H, Tsukamoto T.

Surg Today. 2006;36(7):608-14.


Metastasis: a question of life or death.

Mehlen P, Puisieux A.

Nat Rev Cancer. 2006 Jun;6(6):449-58. Review.


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