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Items: 1 to 20 of 86


Quantitative analysis of fitness and genetic interactions in yeast on a genome scale.

Baryshnikova A, Costanzo M, Kim Y, Ding H, Koh J, Toufighi K, Youn JY, Ou J, San Luis BJ, Bandyopadhyay S, Hibbs M, Hess D, Gingras AC, Bader GD, Troyanskaya OG, Brown GW, Andrews B, Boone C, Myers CL.

Nat Methods. 2010 Dec;7(12):1017-24. doi: 10.1038/nmeth.1534. Epub 2010 Nov 14.


Yeast lipid analysis and quantification by mass spectrometry.

Guan XL, Riezman I, Wenk MR, Riezman H.

Methods Enzymol. 2010;470:369-91. doi: 10.1016/S0076-6879(10)70015-X. Epub 2010 Mar 1.


Exploring gene function and drug action using chemogenomic dosage assays.

Ericson E, Hoon S, St Onge RP, Giaever G, Nislow C.

Methods Enzymol. 2010;470:233-55. doi: 10.1016/S0076-6879(10)70010-0. Epub 2010 Mar 1.


Proteome-wide search reveals unexpected RNA-binding proteins in Saccharomyces cerevisiae.

Tsvetanova NG, Klass DM, Salzman J, Brown PO.

PLoS One. 2010 Sep 10;5(9). pii: e12671. doi: 10.1371/journal.pone.0012671.


Phase II drug metabolizing enzymes.

Jancova P, Anzenbacher P, Anzenbacherova E.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2010 Jun;154(2):103-16. Review.


Cantharidin, a potent and selective PP2A inhibitor, induces an oxidative stress-independent growth inhibition of pancreatic cancer cells through G2/M cell-cycle arrest and apoptosis.

Li W, Xie L, Chen Z, Zhu Y, Sun Y, Miao Y, Xu Z, Han X.

Cancer Sci. 2010 May;101(5):1226-33. doi: 10.1111/j.1349-7006.2010.01523.x. Epub 2010 Feb 5.


The genetic landscape of a cell.

Costanzo M, Baryshnikova A, Bellay J, Kim Y, Spear ED, Sevier CS, Ding H, Koh JL, Toufighi K, Mostafavi S, Prinz J, St Onge RP, VanderSluis B, Makhnevych T, Vizeacoumar FJ, Alizadeh S, Bahr S, Brost RL, Chen Y, Cokol M, Deshpande R, Li Z, Lin ZY, Liang W, Marback M, Paw J, San Luis BJ, Shuteriqi E, Tong AH, van Dyk N, Wallace IM, Whitney JA, Weirauch MT, Zhong G, Zhu H, Houry WA, Brudno M, Ragibizadeh S, Papp B, Pál C, Roth FP, Giaever G, Nislow C, Troyanskaya OG, Bussey H, Bader GD, Gingras AC, Morris QD, Kim PM, Kaiser CA, Myers CL, Andrews BJ, Boone C.

Science. 2010 Jan 22;327(5964):425-31. doi: 10.1126/science.1180823.


Analysis of lipid particles from yeast.

Connerth M, Grillitsch K, Köfeler H, Daum G.

Methods Mol Biol. 2009;579:359-74. doi: 10.1007/978-1-60761-322-0_18.


Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli.

Bennett BD, Kimball EH, Gao M, Osterhout R, Van Dien SJ, Rabinowitz JD.

Nat Chem Biol. 2009 Aug;5(8):593-9. doi: 10.1038/nchembio.186. Epub 2009 Jun 28.


Multiple Motif Scanning to identify methyltransferases from the yeast proteome.

Petrossian TC, Clarke SG.

Mol Cell Proteomics. 2009 Jul;8(7):1516-26. doi: 10.1074/mcp.M900025-MCP200. Epub 2009 Apr 7.


Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology.

Guan XL, Souza CM, Pichler H, Dewhurst G, Schaad O, Kajiwara K, Wakabayashi H, Ivanova T, Castillon GA, Piccolis M, Abe F, Loewith R, Funato K, Wenk MR, Riezman H.

Mol Biol Cell. 2009 Apr;20(7):2083-95. doi: 10.1091/mbc.E08-11-1126. Epub 2009 Feb 18.


Global analysis of the yeast lipidome by quantitative shotgun mass spectrometry.

Ejsing CS, Sampaio JL, Surendranath V, Duchoslav E, Ekroos K, Klemm RW, Simons K, Shevchenko A.

Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2136-41. doi: 10.1073/pnas.0811700106. Epub 2009 Jan 27.


Cell wall integrity MAPK pathway is essential for lipid homeostasis.

Nunez LR, Jesch SA, Gaspar ML, Almaguer C, Villa-Garcia M, Ruiz-Noriega M, Patton-Vogt J, Henry SA.

J Biol Chem. 2008 Dec 5;283(49):34204-17. doi: 10.1074/jbc.M806391200. Epub 2008 Oct 8.


An integrated platform of genomic assays reveals small-molecule bioactivities.

Hoon S, Smith AM, Wallace IM, Suresh S, Miranda M, Fung E, Proctor M, Shokat KM, Zhang C, Davis RW, Giaever G, St Onge RP, Nislow C.

Nat Chem Biol. 2008 Aug;4(8):498-506. doi: 10.1038/nchembio.100. Epub 2008 Jul 11. Erratum in: Nat Chem Biol.2008 Oct;4(10):632.. StOnge, Robert P [corrected to St Onge,Robert P].


S-adenosyl-L-homocysteine hydrolase, key enzyme of methylation metabolism, regulates phosphatidylcholine synthesis and triacylglycerol homeostasis in yeast: implications for homocysteine as a risk factor of atherosclerosis.

Malanovic N, Streith I, Wolinski H, Rechberger G, Kohlwein SD, Tehlivets O.

J Biol Chem. 2008 Aug 29;283(35):23989-99. doi: 10.1074/jbc.M800830200. Epub 2008 Jun 30.


Structural and biochemical properties of lipid particles from the yeast Saccharomyces cerevisiae.

Czabany T, Wagner A, Zweytick D, Lohner K, Leitner E, Ingolic E, Daum G.

J Biol Chem. 2008 Jun 20;283(25):17065-74. doi: 10.1074/jbc.M800401200. Epub 2008 Apr 22.


The chemical genomic portrait of yeast: uncovering a phenotype for all genes.

Hillenmeyer ME, Fung E, Wildenhain J, Pierce SE, Hoon S, Lee W, Proctor M, St Onge RP, Tyers M, Koller D, Altman RB, Davis RW, Nislow C, Giaever G.

Science. 2008 Apr 18;320(5874):362-5. doi: 10.1126/science.1150021.


DNMT1 as a molecular target in a multimodality-resistant phenotype in tumor cells.

Mishra MV, Bisht KS, Sun L, Muldoon-Jacobs K, Awwad R, Kaushal A, Nguyen P, Huang L, Pennington JD, Markovina S, Bradbury CM, Gius D.

Mol Cancer Res. 2008 Feb;6(2):243-9. doi: 10.1158/1541-7786.MCR-07-0373.


Secreted 3-isopropylmalate methyl ester signals invasive growth during amino acid starvation in Saccharomyces cerevisiae.

Dumlao DS, Hertz N, Clarke S.

Biochemistry. 2008 Jan 15;47(2):698-709. Epub 2007 Dec 20.


Genome-wide analysis of barcoded Saccharomyces cerevisiae gene-deletion mutants in pooled cultures.

Pierce SE, Davis RW, Nislow C, Giaever G.

Nat Protoc. 2007;2(11):2958-74.


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