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Items: 1 to 20 of 38


Chronic nicotine consumption does not influence 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis.

Murphy SE, von Weymarn LB, Schutten MM, Kassie F, Modiano JF.

Cancer Prev Res (Phila). 2011 Nov;4(11):1752-60. doi: 10.1158/1940-6207.CAPR-11-0366. Epub 2011 Oct 25.


Akt1 deletion prevents lung tumorigenesis by mutant K-ras.

Hollander MC, Maier CR, Hobbs EA, Ashmore AR, Linnoila RI, Dennis PA.

Oncogene. 2011 Apr 14;30(15):1812-21. doi: 10.1038/onc.2010.556. Epub 2011 Jan 17.


Stimulation of α7 nicotinic acetylcholine receptor by nicotine increases suppressive capacity of naturally occurring CD4+CD25+ regulatory T cells in mice in vitro.

Wang DW, Zhou RB, Yao YM, Zhu XM, Yin YM, Zhao GJ, Dong N, Sheng ZY.

J Pharmacol Exp Ther. 2010 Dec;335(3):553-61. doi: 10.1124/jpet.110.169961. Epub 2010 Sep 15.


Metformin prevents tobacco carcinogen--induced lung tumorigenesis.

Memmott RM, Mercado JR, Maier CR, Kawabata S, Fox SD, Dennis PA.

Cancer Prev Res (Phila). 2010 Sep;3(9):1066-76. doi: 10.1158/1940-6207.CAPR-10-0055. Epub 2010 Sep 1.


Nicotine induces resistance to chemotherapy in nasal epithelial cancer.

Shen T, Le W, Yee A, Kamdar O, Hwang PH, Upadhyay D.

Am J Rhinol Allergy. 2010 Mar-Apr;24(2):e73-7. doi: 10.2500/ajra.2010.24.3456.


Long-term nicotine exposure-induced chemoresistance is mediated by activation of Stat3 and downregulation of ERK1/2 via nAChR and beta-adrenoceptors in human bladder cancer cells.

Chen RJ, Ho YS, Guo HR, Wang YJ.

Toxicol Sci. 2010 May;115(1):118-30. doi: 10.1093/toxsci/kfq028. Epub 2010 Jan 27.


Annual report to the nation on the status of cancer, 1975-2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates.

Edwards BK, Ward E, Kohler BA, Eheman C, Zauber AG, Anderson RN, Jemal A, Schymura MJ, Lansdorp-Vogelaar I, Seeff LC, van Ballegooijen M, Goede SL, Ries LA.

Cancer. 2010 Feb 1;116(3):544-73. doi: 10.1002/cncr.24760.


Nicotine, through upregulating pro-survival signaling, cooperates with NNK to promote transformation.

Nishioka T, Guo J, Yamamoto D, Chen L, Huppi P, Chen CY.

J Cell Biochem. 2010 Jan 1;109(1):152-61. doi: 10.1002/jcb.22392.


Nicotine promotes tumor growth and metastasis in mouse models of lung cancer.

Davis R, Rizwani W, Banerjee S, Kovacs M, Haura E, Coppola D, Chellappan S.

PLoS One. 2009 Oct 20;4(10):e7524. doi: 10.1371/journal.pone.0007524.


Does nicotine replacement therapy cause cancer? Evidence from the Lung Health Study.

Murray RP, Connett JE, Zapawa LM.

Nicotine Tob Res. 2009 Sep;11(9):1076-82. doi: 10.1093/ntr/ntp104. Epub 2009 Jul 1.


A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene.

Luo J, Emanuele MJ, Li D, Creighton CJ, Schlabach MR, Westbrook TF, Wong KK, Elledge SJ.

Cell. 2009 May 29;137(5):835-48. doi: 10.1016/j.cell.2009.05.006.


A central role for Foxp3+ regulatory T cells in K-Ras-driven lung tumorigenesis.

Granville CA, Memmott RM, Balogh A, Mariotti J, Kawabata S, Han W, Lopiccolo J, Foley J, Liewehr DJ, Steinberg SM, Fowler DH, Hollander MC, Dennis PA.

PLoS One. 2009;4(3):e5061. doi: 10.1371/journal.pone.0005061. Epub 2009 Mar 30.


Nicotine induces cell proliferation, invasion and epithelial-mesenchymal transition in a variety of human cancer cell lines.

Dasgupta P, Rizwani W, Pillai S, Kinkade R, Kovacs M, Rastogi S, Banerjee S, Carless M, Kim E, Coppola D, Haura E, Chellappan S.

Int J Cancer. 2009 Jan 1;124(1):36-45. doi: 10.1002/ijc.23894.


Pharmacology of nicotine: addiction, smoking-induced disease, and therapeutics.

Benowitz NL.

Annu Rev Pharmacol Toxicol. 2009;49:57-71. doi: 10.1146/annurev.pharmtox.48.113006.094742. Review.


Multiple roles of nicotine on cell proliferation and inhibition of apoptosis: implications on lung carcinogenesis.

Catassi A, Servent D, Paleari L, Cesario A, Russo P.

Mutat Res. 2008 Sep-Oct;659(3):221-31. doi: 10.1016/j.mrrev.2008.04.002. Epub 2008 Apr 11. Review.


Sulforhodamine B colorimetric assay for cytotoxicity screening.

Vichai V, Kirtikara K.

Nat Protoc. 2006;1(3):1112-6.


Identification of a highly effective rapamycin schedule that markedly reduces the size, multiplicity, and phenotypic progression of tobacco carcinogen-induced murine lung tumors.

Granville CA, Warfel N, Tsurutani J, Hollander MC, Robertson M, Fox SD, Veenstra TD, Issaq HJ, Linnoila RI, Dennis PA.

Clin Cancer Res. 2007 Apr 1;13(7):2281-9.


Mitogen-activated protein kinase pathway was significantly activated in human bronchial epithelial cells by nicotine.

Tsai JR, Chong IW, Chen CC, Lin SR, Sheu CC, Hwang JJ.

DNA Cell Biol. 2006 May;25(5):312-22.


The role of RAS oncogene in survival of patients with lung cancer: a systematic review of the literature with meta-analysis.

Mascaux C, Iannino N, Martin B, Paesmans M, Berghmans T, Dusart M, Haller A, Lothaire P, Meert AP, Noel S, Lafitte JJ, Sculier JP.

Br J Cancer. 2005 Jan 17;92(1):131-9. Review.

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