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Items: 1 to 20 of 45


Real-time imaging of cotranscriptional splicing reveals a kinetic model that reduces noise: implications for alternative splicing regulation.

Schmidt U, Basyuk E, Robert MC, Yoshida M, Villemin JP, Auboeuf D, Aitken S, Bertrand E.

J Cell Biol. 2011 May 30;193(5):819-29. doi: 10.1083/jcb.201009012.


Epigenetics in alternative pre-mRNA splicing.

Luco RF, Allo M, Schor IE, Kornblihtt AR, Misteli T.

Cell. 2011 Jan 7;144(1):16-26. doi: 10.1016/j.cell.2010.11.056. Review.


Splicing-dependent RNA polymerase pausing in yeast.

Alexander RD, Innocente SA, Barrass JD, Beggs JD.

Mol Cell. 2010 Nov 24;40(4):582-93. doi: 10.1016/j.molcel.2010.11.005.


Global analysis of nascent RNA reveals transcriptional pausing in terminal exons.

Carrillo Oesterreich F, Preibisch S, Neugebauer KM.

Mol Cell. 2010 Nov 24;40(4):571-81. doi: 10.1016/j.molcel.2010.11.004.


Crosstalk between mRNA 3' end processing and transcription initiation.

Mapendano CK, Lykke-Andersen S, Kjems J, Bertrand E, Jensen TH.

Mol Cell. 2010 Nov 12;40(3):410-22. doi: 10.1016/j.molcel.2010.10.012.


RiboSys, a high-resolution, quantitative approach to measure the in vivo kinetics of pre-mRNA splicing and 3'-end processing in Saccharomyces cerevisiae.

Alexander RD, Barrass JD, Dichtl B, Kos M, Obtulowicz T, Robert MC, Koper M, Karkusiewicz I, Mariconti L, Tollervey D, Dichtl B, Kufel J, Bertrand E, Beggs JD.

RNA. 2010 Dec;16(12):2570-80. doi: 10.1261/rna.2162610. Epub 2010 Oct 25.


Model-based inference of biochemical parameters and dynamic properties of microbial signal transduction networks.

Schaber J, Klipp E.

Curr Opin Biotechnol. 2011 Feb;22(1):109-16. doi: 10.1016/j.copbio.2010.09.014. Epub 2010 Oct 20. Review.


Cross-talk in transcription, splicing and chromatin: who makes the first call?

Alexander R, Beggs JD.

Biochem Soc Trans. 2010 Oct;38(5):1251-6. doi: 10.1042/BST0381251. Review.


Processivity and coupling in messenger RNA transcription.

Aitken S, Robert MC, Alexander RD, Goryanin I, Bertrand E, Beggs JD.

PLoS One. 2010 Jan 28;5(1):e8845. doi: 10.1371/journal.pone.0008845.


"Cotranscriptionality": the transcription elongation complex as a nexus for nuclear transactions.

Perales R, Bentley D.

Mol Cell. 2009 Oct 23;36(2):178-91. doi: 10.1016/j.molcel.2009.09.018. Review.


Rates of in situ transcription and splicing in large human genes.

Singh J, Padgett RA.

Nat Struct Mol Biol. 2009 Nov;16(11):1128-33. doi: 10.1038/nsmb.1666. Epub 2009 Oct 11.


The spliceosome: a self-organized macromolecular machine in the nucleus?

Rino J, Carmo-Fonseca M.

Trends Cell Biol. 2009 Aug;19(8):375-84. doi: 10.1016/j.tcb.2009.05.004. Epub 2009 Jul 17. Review.


Polyadenylation releases mRNA from RNA polymerase II in a process that is licensed by splicing.

Rigo F, Martinson HG.

RNA. 2009 May;15(5):823-36. doi: 10.1261/rna.1409209. Epub 2009 Mar 20.


The spliceosome: design principles of a dynamic RNP machine.

Wahl MC, Will CL, Lührmann R.

Cell. 2009 Feb 20;136(4):701-18. doi: 10.1016/j.cell.2009.02.009. Review.


"Nought may endure but mutability": spliceosome dynamics and the regulation of splicing.

Smith DJ, Query CC, Konarska MM.

Mol Cell. 2008 Jun 20;30(6):657-66. doi: 10.1016/j.molcel.2008.04.013. Review.


Effects of molecular memory and bursting on fluctuations in gene expression.

Pedraza JM, Paulsson J.

Science. 2008 Jan 18;319(5861):339-43. doi: 10.1126/science.1144331.


A stochastic view of spliceosome assembly and recycling in the nucleus.

Rino J, Carvalho T, Braga J, Desterro JM, Lührmann R, Carmo-Fonseca M.

PLoS Comput Biol. 2007 Oct;3(10):2019-31. Epub 2007 Sep 5.


The transcriptional cycle of HIV-1 in real-time and live cells.

Boireau S, Maiuri P, Basyuk E, de la Mata M, Knezevich A, Pradet-Balade B, Bäcker V, Kornblihtt A, Marcello A, Bertrand E.

J Cell Biol. 2007 Oct 22;179(2):291-304.


Fluctuations, pauses, and backtracking in DNA transcription.

Voliotis M, Cohen N, Molina-París C, Liverpool TB.

Biophys J. 2008 Jan 15;94(2):334-48. Epub 2007 Aug 24.


In vivo dynamics of RNA polymerase II transcription.

Darzacq X, Shav-Tal Y, de Turris V, Brody Y, Shenoy SM, Phair RD, Singer RH.

Nat Struct Mol Biol. 2007 Sep;14(9):796-806. Epub 2007 Aug 5.

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