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Items: 1 to 20 of 30

1.

Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA.

Liu J, Doty T, Gibson B, Heyer WD.

Nat Struct Mol Biol. 2010 Oct;17(10):1260-2. doi: 10.1038/nsmb.1904. Epub 2010 Aug 22.

2.

Purified human BRCA2 stimulates RAD51-mediated recombination.

Jensen RB, Carreira A, Kowalczykowski SC.

Nature. 2010 Oct 7;467(7316):678-83. doi: 10.1038/nature09399.

3.

Regulation of homologous recombination in eukaryotes.

Heyer WD, Ehmsen KT, Liu J.

Annu Rev Genet. 2010;44:113-39. doi: 10.1146/annurev-genet-051710-150955. Review.

4.

Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene.

Meindl A, Hellebrand H, Wiek C, Erven V, Wappenschmidt B, Niederacher D, Freund M, Lichtner P, Hartmann L, Schaal H, Ramser J, Honisch E, Kubisch C, Wichmann HE, Kast K, Deissler H, Engel C, Müller-Myhsok B, Neveling K, Kiechle M, Mathew CG, Schindler D, Schmutzler RK, Hanenberg H.

Nat Genet. 2010 May;42(5):410-4. doi: 10.1038/ng.569. Epub 2010 Apr 18.

PMID:
20400964
5.

Cdk1 targets Srs2 to complete synthesis-dependent strand annealing and to promote recombinational repair.

Saponaro M, Callahan D, Zheng X, Krejci L, Haber JE, Klein HL, Liberi G.

PLoS Genet. 2010 Feb 26;6(2):e1000858. doi: 10.1371/journal.pgen.1000858.

6.

Human Fbh1 helicase contributes to genome maintenance via pro- and anti-recombinase activities.

Fugger K, Mistrik M, Danielsen JR, Dinant C, Falck J, Bartek J, Lukas J, Mailand N.

J Cell Biol. 2009 Sep 7;186(5):655-63. doi: 10.1083/jcb.200812138.

7.

Srs2 disassembles Rad51 filaments by a protein-protein interaction triggering ATP turnover and dissociation of Rad51 from DNA.

Antony E, Tomko EJ, Xiao Q, Krejci L, Lohman TM, Ellenberger T.

Mol Cell. 2009 Jul 10;35(1):105-15. doi: 10.1016/j.molcel.2009.05.026.

8.

Localization of recombination proteins and Srs2 reveals anti-recombinase function in vivo.

Burgess RC, Lisby M, Altmannova V, Krejci L, Sung P, Rothstein R.

J Cell Biol. 2009 Jun 15;185(6):969-81. doi: 10.1083/jcb.200810055. Epub 2009 Jun 8.

9.

Suppression of the double-strand-break-repair defect of the Saccharomyces cerevisiae rad57 mutant.

Fung CW, Mozlin AM, Symington LS.

Genetics. 2009 Apr;181(4):1195-206. doi: 10.1534/genetics.109.100842. Epub 2009 Feb 2.

10.

FANCJ uses its motor ATPase to destabilize protein-DNA complexes, unwind triplexes, and inhibit RAD51 strand exchange.

Sommers JA, Rawtani N, Gupta R, Bugreev DV, Mazin AV, Cantor SB, Brosh RM Jr.

J Biol Chem. 2009 Mar 20;284(12):7505-17. doi: 10.1074/jbc.M809019200. Epub 2009 Jan 16.

11.

Direct imaging of human Rad51 nucleoprotein dynamics on individual DNA molecules.

Hilario J, Amitani I, Baskin RJ, Kowalczykowski SC.

Proc Natl Acad Sci U S A. 2009 Jan 13;106(2):361-8. doi: 10.1073/pnas.0811965106. Epub 2009 Jan 2.

12.

The Srs2 helicase activity is stimulated by Rad51 filaments on dsDNA: implications for crossover incidence during mitotic recombination.

Dupaigne P, Le Breton C, Fabre F, Gangloff S, Le Cam E, Veaute X.

Mol Cell. 2008 Feb 1;29(2):243-54. doi: 10.1016/j.molcel.2007.11.033.

13.

Novel pro- and anti-recombination activities of the Bloom's syndrome helicase.

Bugreev DV, Yu X, Egelman EH, Mazin AV.

Genes Dev. 2007 Dec 1;21(23):3085-94. Epub 2007 Nov 14.

14.

RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments.

Hu Y, Raynard S, Sehorn MG, Lu X, Bussen W, Zheng L, Stark JM, Barnes EL, Chi P, Janscak P, Jasin M, Vogel H, Sung P, Luo G.

Genes Dev. 2007 Dec 1;21(23):3073-84. Epub 2007 Nov 14.

15.

Fluorescent human RAD51 reveals multiple nucleation sites and filament segments tightly associated along a single DNA molecule.

Modesti M, Ristic D, van der Heijden T, Dekker C, van Mameren J, Peterman EJ, Wuite GJ, Kanaar R, Wyman C.

Structure. 2007 May;15(5):599-609.

16.

Phosphorylation of Rad55 on serines 2, 8, and 14 is required for efficient homologous recombination in the recovery of stalled replication forks.

Herzberg K, Bashkirov VI, Rolfsmeier M, Haghnazari E, McDonald WH, Anderson S, Bashkirova EV, Yates JR 3rd, Heyer WD.

Mol Cell Biol. 2006 Nov;26(22):8396-409. Epub 2006 Sep 11.

17.

Crosstalk between SUMO and ubiquitin on PCNA is mediated by recruitment of the helicase Srs2p.

Papouli E, Chen S, Davies AA, Huttner D, Krejci L, Sung P, Ulrich HD.

Mol Cell. 2005 Jul 1;19(1):123-33.

18.

SUMO-modified PCNA recruits Srs2 to prevent recombination during S phase.

Pfander B, Moldovan GL, Sacher M, Hoege C, Jentsch S.

Nature. 2005 Jul 21;436(7049):428-33. Epub 2005 Jun 1.

PMID:
15931174
19.

The RAD51 gene family, genetic instability and cancer.

Thacker J.

Cancer Lett. 2005 Mar 10;219(2):125-35. Review.

PMID:
15723711
20.

Choreography of the DNA damage response: spatiotemporal relationships among checkpoint and repair proteins.

Lisby M, Barlow JH, Burgess RC, Rothstein R.

Cell. 2004 Sep 17;118(6):699-713.

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