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Items: 1 to 20 of 31

1.

GalR2-positive allosteric modulator exhibits anticonvulsant effects in animal models.

Lu X, Roberts E, Xia F, Sanchez-Alavez M, Liu T, Baldwin R, Wu S, Chang J, Wasterlain CG, Bartfai T.

Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15229-34. doi: 10.1073/pnas.1008986107. Epub 2010 Jul 26.

2.

Engineering galanin analogues that discriminate between GalR1 and GalR2 receptor subtypes and exhibit anticonvulsant activity following systemic delivery.

Robertson CR, Scholl EA, Pruess TH, Green BR, White HS, Bulaj G.

J Med Chem. 2010 Feb 25;53(4):1871-5. doi: 10.1021/jm9018349.

3.

Neuropeptides in learning and memory processes with focus on galanin.

Ogren SO, Kuteeva E, Elvander-Tottie E, Hökfelt T.

Eur J Pharmacol. 2010 Jan 10;626(1):9-17. doi: 10.1016/j.ejphar.2009.09.070. Epub 2009 Oct 18. Review.

PMID:
19837050
4.

Effects of galanin on monoaminergic systems and HPA axis: Potential mechanisms underlying the effects of galanin on addiction- and stress-related behaviors.

Picciotto MR, Brabant C, Einstein EB, Kamens HM, Neugebauer NM.

Brain Res. 2010 Feb 16;1314:206-18. doi: 10.1016/j.brainres.2009.08.033. Epub 2009 Aug 20. Review.

5.

Developing novel antiepileptic drugs: characterization of NAX 5055, a systemically-active galanin analog, in epilepsy models.

White HS, Scholl EA, Klein BD, Flynn SP, Pruess TH, Green BR, Zhang L, Bulaj G.

Neurotherapeutics. 2009 Apr;6(2):372-80. doi: 10.1016/j.nurt.2009.01.001.

6.

Structural requirements for a lipoamino acid in modulating the anticonvulsant activities of systemically active galanin analogues.

Zhang L, Robertson CR, Green BR, Pruess TH, White HS, Bulaj G.

J Med Chem. 2009 Mar 12;52(5):1310-6. doi: 10.1021/jm801397w.

7.

Design, synthesis, and characterization of high-affinity, systemically-active galanin analogues with potent anticonvulsant activities.

Bulaj G, Green BR, Lee HK, Robertson CR, White K, Zhang L, Sochanska M, Flynn SP, Scholl EA, Pruess TH, Smith MD, White HS.

J Med Chem. 2008 Dec 25;51(24):8038-47. doi: 10.1021/jm801088x.

PMID:
19053761
8.

Biaryl phosphane ligands in palladium-catalyzed amination.

Surry DS, Buchwald SL.

Angew Chem Int Ed Engl. 2008;47(34):6338-61. doi: 10.1002/anie.200800497. Review.

9.

Galanin impairs cognitive abilities in rodents: relevance to Alzheimer's disease.

Crawley JN.

Cell Mol Life Sci. 2008 Jun;65(12):1836-41. doi: 10.1007/s00018-008-8158-3. Review.

10.

Galanin in Alzheimer's disease: neuroinhibitory or neuroprotective?

Counts SE, Perez SE, Mufson EJ.

Cell Mol Life Sci. 2008 Jun;65(12):1842-53. doi: 10.1007/s00018-008-8159-2. Review.

11.

The brain galanin receptors: targets for novel antidepressant drugs.

Lu X, Sharkey L, Bartfai T.

CNS Neurol Disord Drug Targets. 2007 Jun;6(3):183-92. Review.

PMID:
17511615
12.

Galanin: a novel therapeutic target for depression, anxiety disorders and drug addiction?

Holmes A, Picciotto MR.

CNS Neurol Disord Drug Targets. 2006 Apr;5(2):225-32. Review.

PMID:
16611095
13.

Galanin and its receptors in neurological disorders.

Lundström L, Elmquist A, Bartfai T, Langel U.

Neuromolecular Med. 2005;7(1-2):157-80. Review.

PMID:
16052044
14.
15.

Galnon--a low-molecular weight ligand of the galanin receptors.

Sollenberg U, Bartfai T, Langel U.

Neuropeptides. 2005 Jun;39(3):161-3. Epub 2005 Feb 2. Review.

PMID:
15944006
16.

Galanin receptor ligands.

Lu X, Lundström L, Langel U, Bartfai T.

Neuropeptides. 2005 Jun;39(3):143-6. Epub 2005 Feb 1. Review.

PMID:
15944002
17.

Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests.

Bartfai T, Lu X, Badie-Mahdavi H, Barr AM, Mazarati A, Hua XY, Yaksh T, Haberhauer G, Ceide SC, Trembleau L, Somogyi L, Kröck L, Rebek J Jr.

Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10470-5. Epub 2004 Jul 6.

18.

Galanin type 2 receptors regulate neuronal survival, susceptibility to seizures and seizure-induced neurogenesis in the dentate gyrus.

Mazarati A, Lu X, Kilk K, Langel U, Wasterlain C, Bartfai T.

Eur J Neurosci. 2004 Jun;19(12):3235-44.

PMID:
15217380
19.

Distribution and regulation of galanin receptor 1 messenger RNA in the forebrain of wild type and galanin-transgenic mice.

Hohmann JG, Juréus A, Teklemichael DN, Matsumoto AM, Clifton DK, Steiner RA.

Neuroscience. 2003;117(1):105-17.

PMID:
12605897
20.

The participation of galanin in pain processing at the spinal level.

Liu HX, Hökfelt T.

Trends Pharmacol Sci. 2002 Oct;23(10):468-74. Review.

PMID:
12368071

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