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Items: 1 to 20 of 172

1.

Transglutaminase 2 and its role in pulmonary fibrosis.

Olsen KC, Sapinoro RE, Kottmann RM, Kulkarni AA, Iismaa SE, Johnson GV, Thatcher TH, Phipps RP, Sime PJ.

Am J Respir Crit Care Med. 2011 Sep 15;184(6):699-707. doi: 10.1164/rccm.201101-0013OC. Epub 2011 Jun 23.

2.

Unconventional secretion of tissue transglutaminase involves phospholipid-dependent delivery into recycling endosomes.

Zemskov EA, Mikhailenko I, Hsia RC, Zaritskaya L, Belkin AM.

PLoS One. 2011 Apr 27;6(4):e19414. doi: 10.1371/journal.pone.0019414.

3.

TG2 transamidating activity acts as a reostat controlling the interplay between apoptosis and autophagy.

Rossin F, D'Eletto M, Macdonald D, Farrace MG, Piacentini M.

Amino Acids. 2012 May;42(5):1793-802. doi: 10.1007/s00726-011-0899-x. Epub 2011 Apr 10.

PMID:
21479826
4.

Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells.

Antonyak MA, Li B, Boroughs LK, Johnson JL, Druso JE, Bryant KL, Holowka DA, Cerione RA.

Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):4852-7. doi: 10.1073/pnas.1017667108. Epub 2011 Feb 28. Erratum in: Proc Natl Acad Sci U S A. 2011 Oct 18;108(42):17569.

5.

Novel chemo-sensitizing agent, ERW1227B, impairs cellular motility and enhances cell death in glioblastomas.

Yuan L, Holmes TC, Watts RE, Khosla C, Broekelmann TJ, Mecham R, Zheng H, Izaguirre EW, Rich KM.

J Neurooncol. 2011 Jun;103(2):207-19. doi: 10.1007/s11060-010-0379-2. Epub 2010 Sep 8.

6.

Appearance of tissue transglutaminase in astrocytes in multiple sclerosis lesions: a role in cell adhesion and migration?

van Strien ME, Drukarch B, Bol JG, van der Valk P, van Horssen J, Gerritsen WH, Breve JJ, van Dam AM.

Brain Pathol. 2011 Jan;21(1):44-54. doi: 10.1111/j.1750-3639.2010.00428.x. Epub 2010 Aug 20.

PMID:
20731658
7.

Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease.

McConoughey SJ, Basso M, Niatsetskaya ZV, Sleiman SF, Smirnova NA, Langley BC, Mahishi L, Cooper AJ, Antonyak MA, Cerione RA, Li B, Starkov A, Chaturvedi RK, Beal MF, Coppola G, Geschwind DH, Ryu H, Xia L, Iismaa SE, Pallos J, Pasternack R, Hils M, Fan J, Raymond LA, Marsh JL, Thompson LM, Ratan RR.

EMBO Mol Med. 2010 Sep;2(9):349-70. doi: 10.1002/emmm.201000084.

8.

Mutational effects and the evolution of new protein functions.

Soskine M, Tawfik DS.

Nat Rev Genet. 2010 Aug;11(8):572-82. doi: 10.1038/nrg2808. Review.

PMID:
20634811
9.

Transglutaminase 2: a multi-tasking protein in the complex circuitry of inflammation and cancer.

Mehta K, Kumar A, Kim HI.

Biochem Pharmacol. 2010 Dec 15;80(12):1921-9. doi: 10.1016/j.bcp.2010.06.029. Epub 2010 Jun 25. Review.

PMID:
20599779
10.

The transglutaminase 2 gene is aberrantly hypermethylated in glioma.

Dyer LM, Schooler KP, Ai L, Klop C, Qiu J, Robertson KD, Brown KD.

J Neurooncol. 2011 Feb;101(3):429-40. doi: 10.1007/s11060-010-0277-7. Epub 2010 Jul 3.

11.

Redox regulation of transglutaminase 2 activity.

Stamnaes J, Pinkas DM, Fleckenstein B, Khosla C, Sollid LM.

J Biol Chem. 2010 Aug 13;285(33):25402-9. doi: 10.1074/jbc.M109.097162. Epub 2010 Jun 14.

12.

Decreased S-nitrosylation of tissue transglutaminase contributes to age-related increases in vascular stiffness.

Santhanam L, Tuday EC, Webb AK, Dowzicky P, Kim JH, Oh YJ, Sikka G, Kuo M, Halushka MK, Macgregor AM, Dunn J, Gutbrod S, Yin D, Shoukas A, Nyhan D, Flavahan NA, Belkin AM, Berkowitz DE.

Circ Res. 2010 Jul 9;107(1):117-25. doi: 10.1161/CIRCRESAHA.109.215228. Epub 2010 May 20. Erratum in: Circ Res. 2011 Apr 29;108(9):e12.

13.

Transglutaminase 2 protects against ischemic stroke.

Filiano AJ, Tucholski J, Dolan PJ, Colak G, Johnson GV.

Neurobiol Dis. 2010 Sep;39(3):334-43. doi: 10.1016/j.nbd.2010.04.018. Epub 2010 May 6.

14.

Crystal structure of human transglutaminase 2 in complex with adenosine triphosphate.

Han BG, Cho JW, Cho YD, Jeong KC, Kim SY, Lee BI.

Int J Biol Macromol. 2010 Aug 1;47(2):190-5. doi: 10.1016/j.ijbiomac.2010.04.023. Epub 2010 May 5.

PMID:
20450932
15.

Opposing effects of two tissue transglutaminase protein isoforms in neuroblastoma cell differentiation.

Tee AE, Marshall GM, Liu PY, Xu N, Haber M, Norris MD, Iismaa SE, Liu T.

J Biol Chem. 2010 Feb 5;285(6):3561-7. doi: 10.1074/jbc.M109.053041. Epub 2009 Dec 10.

16.

Transglutaminase 2 is involved in autophagosome maturation.

D'Eletto M, Farrace MG, Falasca L, Reali V, Oliverio S, Melino G, Griffin M, Fimia GM, Piacentini M.

Autophagy. 2009 Nov;5(8):1145-54.

PMID:
19955852
17.

Functional significance of five noncanonical Ca2+-binding sites of human transglutaminase 2 characterized by site-directed mutagenesis.

Király R, Csosz E, Kurtán T, Antus S, Szigeti K, Simon-Vecsei Z, Korponay-Szabó IR, Keresztessy Z, Fésüs L.

FEBS J. 2009 Dec;276(23):7083-96. doi: 10.1111/j.1742-4658.2009.07420.x. Epub 2009 Oct 29.

18.

Transglutaminase 2 suppresses apoptosis by modulating caspase 3 and NF-kappaB activity in hypoxic tumor cells.

Jang GY, Jeon JH, Cho SY, Shin DM, Kim CW, Jeong EM, Bae HC, Kim TW, Lee SH, Choi Y, Lee DS, Park SC, Kim IG.

Oncogene. 2010 Jan 21;29(3):356-67. doi: 10.1038/onc.2009.342. Epub 2009 Oct 19.

PMID:
19838207
19.

Transglutaminase 2 as a cisplatin resistance marker in non-small cell lung cancer.

Park KS, Kim HK, Lee JH, Choi YB, Park SY, Yang SH, Kim SY, Hong KM.

J Cancer Res Clin Oncol. 2010 Apr;136(4):493-502. doi: 10.1007/s00432-009-0681-6. Epub 2009 Sep 18.

PMID:
19763620
20.

Increased TG2 expression can result in induction of transforming growth factor beta1, causing increased synthesis and deposition of matrix proteins, which can be regulated by nitric oxide.

Telci D, Collighan RJ, Basaga H, Griffin M.

J Biol Chem. 2009 Oct 23;284(43):29547-58. doi: 10.1074/jbc.M109.041806. Epub 2009 Aug 5.

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