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Items: 1 to 20 of 46


Childhood maltreatment, the corticotropin-releasing hormone receptor gene and adult depression in the general population.

Grabe HJ, Schwahn C, Appel K, Mahler J, Schulz A, Spitzer C, Fenske K, Barnow S, Lucht M, Freyberger HJ, John U, Teumer A, Wallaschofski H, Nauck M, Völzke H.

Am J Med Genet B Neuropsychiatr Genet. 2010 Dec 5;153B(8):1483-93. doi: 10.1002/ajmg.b.31131. Epub 2010 Oct 18.


Effect of childhood physical abuse on cortisol stress response.

Carpenter LL, Shattuck TT, Tyrka AR, Geracioti TD, Price LH.

Psychopharmacology (Berl). 2011 Mar;214(1):367-75. doi: 10.1007/s00213-010-2007-4. Epub 2010 Sep 14.


Increased expression level of corticotropin-releasing hormone in the amygdala and in the hypothalamus in rats exposed to chronic unpredictable mild stress.

Wang SS, Yan XB, Hofman MA, Swaab DF, Zhou JN.

Neurosci Bull. 2010 Aug;26(4):297-303. doi: 10.1007/s12264-010-0329-1.


Effect of Childhood Trauma on Adult Depression and Neuroendocrine Function: Sex-Specific Moderation by CRH Receptor 1 Gene.

Heim C, Bradley B, Mletzko TC, Deveau TC, Musselman DL, Nemeroff CB, Ressler KJ, Binder EB.

Front Behav Neurosci. 2009 Nov 6;3:41. doi: 10.3389/neuro.08.041.2009. eCollection 2009.


Polymorphisms in CRHR1 and the serotonin transporter loci: gene x gene x environment interactions on depressive symptoms.

Ressler KJ, Bradley B, Mercer KB, Deveau TC, Smith AK, Gillespie CF, Nemeroff CB, Cubells JF, Binder EB.

Am J Med Genet B Neuropsychiatr Genet. 2010 Apr 5;153B(3):812-24. doi: 10.1002/ajmg.b.31052.


Translating the neuroscience of alcoholism into clinical treatments: from blocking the buzz to curing the blues.

Heilig M, Thorsell A, Sommer WH, Hansson AC, Ramchandani VA, George DT, Hommer D, Barr CS.

Neurosci Biobehav Rev. 2010 Nov;35(2):334-44. doi: 10.1016/j.neubiorev.2009.11.018. Epub 2009 Nov 24. Review.


Interactive effect of stressful life events and the serotonin transporter 5-HTTLPR genotype on posttraumatic stress disorder diagnosis in 2 independent populations.

Xie P, Kranzler HR, Poling J, Stein MB, Anton RF, Brady K, Weiss RD, Farrer L, Gelernter J.

Arch Gen Psychiatry. 2009 Nov;66(11):1201-9. doi: 10.1001/archgenpsychiatry.2009.153.


H2 haplotype at chromosome 17q21.31 protects against childhood sexual abuse-associated risk for alcohol consumption and dependence.

Nelson EC, Agrawal A, Pergadia ML, Wang JC, Whitfield JB, Saccone FS, Kern J, Grant JD, Schrage AJ, Rice JP, Montgomery GW, Heath AC, Goate AM, Martin NG, Madden PA.

Addict Biol. 2010 Jan;15(1):1-11. doi: 10.1111/j.1369-1600.2009.00181.x.


Protective effect of CRHR1 gene variants on the development of adult depression following childhood maltreatment: replication and extension.

Polanczyk G, Caspi A, Williams B, Price TS, Danese A, Sugden K, Uher R, Poulton R, Moffitt TE.

Arch Gen Psychiatry. 2009 Sep;66(9):978-85. doi: 10.1001/archgenpsychiatry.2009.114.


Adverse childhood events as risk factors for substance dependence: partial mediation by mood and anxiety disorders.

Douglas KR, Chan G, Gelernter J, Arias AJ, Anton RF, Weiss RD, Brady K, Poling J, Farrer L, Kranzler HR.

Addict Behav. 2010 Jan;35(1):7-13. doi: 10.1016/j.addbeh.2009.07.004. Epub 2009 Aug 8.


Subtypes of major depression in substance dependence.

Niciu MJ, Chan G, Gelernter J, Arias AJ, Douglas K, Weiss R, Anton RF, Farrer L, Cubells JF, Kranzler HR.

Addiction. 2009 Oct;104(10):1700-9. doi: 10.1111/j.1360-0443.2009.02672.x. Epub 2009 Aug 4.


Interaction of childhood maltreatment with the corticotropin-releasing hormone receptor gene: effects on hypothalamic-pituitary-adrenal axis reactivity.

Tyrka AR, Price LH, Gelernter J, Schepker C, Anderson GM, Carpenter LL.

Biol Psychiatry. 2009 Oct 1;66(7):681-5. doi: 10.1016/j.biopsych.2009.05.012. Epub 2009 Jul 12.


Effect of childhood emotional abuse and age on cortisol responsivity in adulthood.

Carpenter LL, Tyrka AR, Ross NS, Khoury L, Anderson GM, Price LH.

Biol Psychiatry. 2009 Jul 1;66(1):69-75. doi: 10.1016/j.biopsych.2009.02.030. Epub 2009 Apr 17.


Sources of unreliability in the diagnosis of substance dependence.

Feinn R, Gelernter J, Cubells JF, Farrer L, Kranzler HR.

J Stud Alcohol Drugs. 2009 May;70(3):475-81.


Glucocorticoid inhibition in the treatment of depression: can we think outside the endocrine hypothalamus?

Kling MA, Coleman VH, Schulkin J.

Depress Anxiety. 2009;26(7):641-9. doi: 10.1002/da.20546. Review.


Synaptic physiology of central CRH system.

Gallagher JP, Orozco-Cabal LF, Liu J, Shinnick-Gallagher P.

Eur J Pharmacol. 2008 Apr 7;583(2-3):215-25. doi: 10.1016/j.ejphar.2007.11.075. Epub 2008 Feb 1. Review.


Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene.

Bradley RG, Binder EB, Epstein MP, Tang Y, Nair HP, Liu W, Gillespie CF, Berg T, Evces M, Newport DJ, Stowe ZN, Heim CM, Nemeroff CB, Schwartz A, Cubells JF, Ressler KJ.

Arch Gen Psychiatry. 2008 Feb;65(2):190-200. doi: 10.1001/archgenpsychiatry.2007.26.


A comparison of factors associated with substance-induced versus independent depressions.

Schuckit MA, Smith TL, Danko GP, Pierson J, Trim R, Nurnberger JI, Kramer J, Kuperman S, Bierut LJ, Hesselbrock V.

J Stud Alcohol Drugs. 2007 Nov;68(6):805-12.


Decreased adrenocorticotropic hormone and cortisol responses to stress in healthy adults reporting significant childhood maltreatment.

Carpenter LL, Carvalho JP, Tyrka AR, Wier LM, Mello AF, Mello MF, Anderson GM, Wilkinson CW, Price LH.

Biol Psychiatry. 2007 Nov 15;62(10):1080-7. Epub 2007 Jul 27.


Interaction between CRHR1 gene and stressful life events predicts adolescent heavy alcohol use.

Blomeyer D, Treutlein J, Esser G, Schmidt MH, Schumann G, Laucht M.

Biol Psychiatry. 2008 Jan 15;63(2):146-51. Epub 2007 Jun 27.


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