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Items: 1 to 20 of 86

1.

Lgr4 is required for Paneth cell differentiation and maintenance of intestinal stem cells ex vivo.

Mustata RC, Van Loy T, Lefort A, Libert F, Strollo S, Vassart G, Garcia MI.

EMBO Rep. 2011 Jun;12(6):558-64. doi: 10.1038/embor.2011.52. Epub 2011 Apr 21.

2.

Fibroblast growth factor receptor-3 (FGFR-3) regulates expression of paneth cell lineage-specific genes in intestinal epithelial cells through both TCF4/beta-catenin-dependent and -independent signaling pathways.

Brodrick B, Vidrich A, Porter E, Bradley L, Buzan JM, Cohn SM.

J Biol Chem. 2011 May 27;286(21):18515-25. doi: 10.1074/jbc.M111.229252. Epub 2011 Mar 9.

3.

Distinct ATOH1 and Neurog3 requirements define tuft cells as a new secretory cell type in the intestinal epithelium.

Gerbe F, van Es JH, Makrini L, Brulin B, Mellitzer G, Robine S, Romagnolo B, Shroyer NF, Bourgaux JF, Pignodel C, Clevers H, Jay P.

J Cell Biol. 2011 Mar 7;192(5):767-80. doi: 10.1083/jcb.201010127.

4.

Genetic evidence that intestinal Notch functions vary regionally and operate through a common mechanism of Math1 repression.

Kim TH, Shivdasani RA.

J Biol Chem. 2011 Apr 1;286(13):11427-33. doi: 10.1074/jbc.M110.188797. Epub 2011 Jan 31.

5.

GATA factors regulate proliferation, differentiation, and gene expression in small intestine of mature mice.

Beuling E, Baffour-Awuah NY, Stapleton KA, Aronson BE, Noah TK, Shroyer NF, Duncan SA, Fleet JC, Krasinski SD.

Gastroenterology. 2011 Apr;140(4):1219-1229.e1-2. doi: 10.1053/j.gastro.2011.01.033. Epub 2011 Jan 21.

6.

Vertebrate intestinal endoderm development.

Spence JR, Lauf R, Shroyer NF.

Dev Dyn. 2011 Mar;240(3):501-20. doi: 10.1002/dvdy.22540. Epub 2011 Jan 18. Review.

7.

Dll1- and dll4-mediated notch signaling are required for homeostasis of intestinal stem cells.

Pellegrinet L, Rodilla V, Liu Z, Chen S, Koch U, Espinosa L, Kaestner KH, Kopan R, Lewis J, Radtke F.

Gastroenterology. 2011 Apr;140(4):1230-1240.e1-7. doi: 10.1053/j.gastro.2011.01.005. Epub 2011 Jan 14.

8.

Complex interplay between β-catenin signalling and Notch effectors in intestinal tumorigenesis.

Peignon G, Durand A, Cacheux W, Ayrault O, Terris B, Laurent-Puig P, Shroyer NF, Van Seuningen I, Honjo T, Perret C, Romagnolo B.

Gut. 2011 Feb;60(2):166-76. doi: 10.1136/gut.2009.204719.

9.

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts.

Sato T, van Es JH, Snippert HJ, Stange DE, Vries RG, van den Born M, Barker N, Shroyer NF, van de Wetering M, Clevers H.

Nature. 2011 Jan 20;469(7330):415-8. doi: 10.1038/nature09637. Epub 2010 Nov 28.

10.

Cdx2 levels modulate intestinal epithelium maturity and Paneth cell development.

Crissey MA, Guo RJ, Funakoshi S, Kong J, Liu J, Lynch JP.

Gastroenterology. 2011 Feb;140(2):517-528.e8. doi: 10.1053/j.gastro.2010.11.033. Epub 2010 Nov 13.

11.

Altered intestinal epithelial homeostasis in mice with intestine-specific deletion of the Krüppel-like factor 4 gene.

Ghaleb AM, McConnell BB, Kaestner KH, Yang VW.

Dev Biol. 2011 Jan 15;349(2):310-20. doi: 10.1016/j.ydbio.2010.11.001. Epub 2010 Nov 9.

12.

Intestinal stem cells lacking the Math1 tumour suppressor are refractory to Notch inhibitors.

van Es JH, de Geest N, van de Born M, Clevers H, Hassan BA.

Nat Commun. 2010 May 17;1:18. doi: 10.1038/ncomms1017.

13.

Mouse atonal homolog 1 directs intestinal progenitors to secretory cell rather than absorptive cell fate.

VanDussen KL, Samuelson LC.

Dev Biol. 2010 Oct 15;346(2):215-23. doi: 10.1016/j.ydbio.2010.07.026. Epub 2010 Aug 4.

14.

Atonal homolog 1 is required for growth and differentiation effects of notch/gamma-secretase inhibitors on normal and cancerous intestinal epithelial cells.

Kazanjian A, Noah T, Brown D, Burkart J, Shroyer NF.

Gastroenterology. 2010 Sep;139(3):918-28, 928.e1-6. doi: 10.1053/j.gastro.2010.05.081. Epub 2010 Jun 2.

15.

Cell Lineage metastability in Gfi1-deficient mouse intestinal epithelium.

Bjerknes M, Cheng H.

Dev Biol. 2010 Sep 1;345(1):49-63. doi: 10.1016/j.ydbio.2010.06.021. Epub 2010 Jun 20.

16.

Hepatocyte nuclear factor 1alpha and beta control terminal differentiation and cell fate commitment in the gut epithelium.

D'Angelo A, Bluteau O, Garcia-Gonzalez MA, Gresh L, Doyen A, Garbay S, Robine S, Pontoglio M.

Development. 2010 May;137(9):1573-82. doi: 10.1242/dev.044420.

17.

Gut endocrine cell development.

May CL, Kaestner KH.

Mol Cell Endocrinol. 2010 Jul 8;323(1):70-5. doi: 10.1016/j.mce.2009.12.009. Epub 2009 Dec 16. Review. No abstract available.

18.

RANKL is necessary and sufficient to initiate development of antigen-sampling M cells in the intestinal epithelium.

Knoop KA, Kumar N, Butler BR, Sakthivel SK, Taylor RT, Nochi T, Akiba H, Yagita H, Kiyono H, Williams IR.

J Immunol. 2009 Nov 1;183(9):5738-47. doi: 10.4049/jimmunol.0901563. Epub 2009 Oct 14.

19.

Hepatocyte nuclear factor 4alpha, a key factor for homeostasis, cell architecture, and barrier function of the adult intestinal epithelium.

Cattin AL, Le Beyec J, Barreau F, Saint-Just S, Houllier A, Gonzalez FJ, Robine S, Pinçon-Raymond M, Cardot P, Lacasa M, Ribeiro A.

Mol Cell Biol. 2009 Dec;29(23):6294-308. doi: 10.1128/MCB.00939-09. Epub 2009 Oct 5.

20.

SAM pointed domain ETS factor (SPDEF) regulates terminal differentiation and maturation of intestinal goblet cells.

Noah TK, Kazanjian A, Whitsett J, Shroyer NF.

Exp Cell Res. 2010 Feb 1;316(3):452-65. doi: 10.1016/j.yexcr.2009.09.020. Epub 2009 Sep 26.

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