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Items: 1 to 20 of 70

1.

Protein arginine methyltransferase 5 accelerates tumor growth by arginine methylation of the tumor suppressor programmed cell death 4.

Powers MA, Fay MM, Factor RE, Welm AL, Ullman KS.

Cancer Res. 2011 Aug 15;71(16):5579-87. doi: 10.1158/0008-5472.CAN-11-0458. Epub 2011 Jun 23.

2.

Brief report: combined chemical treatment enables Oct4-induced reprogramming from mouse embryonic fibroblasts.

Yuan X, Wan H, Zhao X, Zhu S, Zhou Q, Ding S.

Stem Cells. 2011 Mar;29(3):549-53. doi: 10.1002/stem.594.

3.

JAK2V617F-mediated phosphorylation of PRMT5 downregulates its methyltransferase activity and promotes myeloproliferation.

Liu F, Zhao X, Perna F, Wang L, Koppikar P, Abdel-Wahab O, Harr MW, Levine RL, Xu H, Tefferi A, Deblasio A, Hatlen M, Menendez S, Nimer SD.

Cancer Cell. 2011 Feb 15;19(2):283-94. doi: 10.1016/j.ccr.2010.12.020.

4.

A germ cell-specific gene, Prmt5, works in somatic cell reprogramming.

Nagamatsu G, Kosaka T, Kawasumi M, Kinoshita T, Takubo K, Akiyama H, Sudo T, Kobayashi T, Oya M, Suda T.

J Biol Chem. 2011 Mar 25;286(12):10641-8. doi: 10.1074/jbc.M110.216390. Epub 2011 Jan 26.

5.

Crosstalk between Arg 1175 methylation and Tyr 1173 phosphorylation negatively modulates EGFR-mediated ERK activation.

Hsu JM, Chen CT, Chou CK, Kuo HP, Li LY, Lin CY, Lee HJ, Wang YN, Liu M, Liao HW, Shi B, Lai CC, Bedford MT, Tsai CH, Hung MC.

Nat Cell Biol. 2011 Feb;13(2):174-81. doi: 10.1038/ncb2158. Epub 2011 Jan 23.

6.

Prmt5 is essential for early mouse development and acts in the cytoplasm to maintain ES cell pluripotency.

Tee WW, Pardo M, Theunissen TW, Yu L, Choudhary JS, Hajkova P, Surani MA.

Genes Dev. 2010 Dec 15;24(24):2772-7. doi: 10.1101/gad.606110.

7.

RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity.

Guderian G, Peter C, Wiesner J, Sickmann A, Schulze-Osthoff K, Fischer U, Grimmler M.

J Biol Chem. 2011 Jan 21;286(3):1976-86. doi: 10.1074/jbc.M110.148486. Epub 2010 Nov 16.

8.

Analysis of Jmjd6 cellular localization and testing for its involvement in histone demethylation.

Hahn P, Wegener I, Burrells A, Böse J, Wolf A, Erck C, Butler D, Schofield CJ, Böttger A, Lengeling A.

PLoS One. 2010 Oct 29;5(10):e13769. doi: 10.1371/journal.pone.0013769.

9.

Arginine methylation mediated by the Arabidopsis homolog of PRMT5 is essential for proper pre-mRNA splicing.

Deng X, Gu L, Liu C, Lu T, Lu F, Lu Z, Cui P, Pei Y, Wang B, Hu S, Cao X.

Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):19114-9. doi: 10.1073/pnas.1009669107. Epub 2010 Oct 18.

10.

Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase.

Aggarwal P, Vaites LP, Kim JK, Mellert H, Gurung B, Nakagawa H, Herlyn M, Hua X, Rustgi AK, McMahon SB, Diehl JA.

Cancer Cell. 2010 Oct 19;18(4):329-40. doi: 10.1016/j.ccr.2010.08.012.

11.

The expression of myogenic microRNAs indirectly requires protein arginine methyltransferase (Prmt)5 but directly requires Prmt4.

Mallappa C, Hu YJ, Shamulailatpam P, Tae S, Sif S, Imbalzano AN.

Nucleic Acids Res. 2011 Mar;39(4):1243-55. doi: 10.1093/nar/gkq896. Epub 2010 Oct 14.

12.

Identification of a PRMT5-dependent repressor complex linked to silencing of human fetal globin gene expression.

Rank G, Cerruti L, Simpson RJ, Moritz RL, Jane SM, Zhao Q.

Blood. 2010 Sep 2;116(9):1585-92. doi: 10.1182/blood-2009-10-251116. Epub 2010 May 21.

13.

PRMT5 regulates Golgi apparatus structure through methylation of the golgin GM130.

Zhou Z, Sun X, Zou Z, Sun L, Zhang T, Guo S, Wen Y, Liu L, Wang Y, Qin J, Li L, Gong W, Bao S.

Cell Res. 2010 Sep;20(9):1023-33. doi: 10.1038/cr.2010.56. Epub 2010 Apr 27.

PMID:
20421892
14.

Advances in the understanding of haemoglobin switching.

Sankaran VG, Xu J, Orkin SH.

Br J Haematol. 2010 Apr;149(2):181-94. doi: 10.1111/j.1365-2141.2010.08105.x. Epub 2010 Mar 1. Review.

15.

Methylation of ribosomal protein S10 by protein-arginine methyltransferase 5 regulates ribosome biogenesis.

Ren J, Wang Y, Liang Y, Zhang Y, Bao S, Xu Z.

J Biol Chem. 2010 Apr 23;285(17):12695-705. doi: 10.1074/jbc.M110.103911. Epub 2010 Feb 16.

16.

Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members.

Vagin VV, Wohlschlegel J, Qu J, Jonsson Z, Huang X, Chuma S, Girard A, Sachidanandam R, Hannon GJ, Aravin AA.

Genes Dev. 2009 Aug 1;23(15):1749-62. doi: 10.1101/gad.1814809. Epub 2009 Jul 7.

17.

Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing.

Webby CJ, Wolf A, Gromak N, Dreger M, Kramer H, Kessler B, Nielsen ML, Schmitz C, Butler DS, Yates JR 3rd, Delahunty CM, Hahn P, Lengeling A, Mann M, Proudfoot NJ, Schofield CJ, Böttger A.

Science. 2009 Jul 3;325(5936):90-3. doi: 10.1126/science.1175865.

18.

PRMT5 is required for cell-cycle progression and p53 tumor suppressor function.

Scoumanne A, Zhang J, Chen X.

Nucleic Acids Res. 2009 Aug;37(15):4965-76. doi: 10.1093/nar/gkp516. Epub 2009 Jun 15.

19.

Caenorhabditis elegans protein arginine methyltransferase PRMT-5 negatively regulates DNA damage-induced apoptosis.

Yang M, Sun J, Sun X, Shen Q, Gao Z, Yang C.

PLoS Genet. 2009 Jun;5(6):e1000514. doi: 10.1371/journal.pgen.1000514. Epub 2009 Jun 12.

20.

Role of pICLn in methylation of Sm proteins by PRMT5.

Pesiridis GS, Diamond E, Van Duyne GD.

J Biol Chem. 2009 Aug 7;284(32):21347-59. doi: 10.1074/jbc.M109.015578. Epub 2009 Jun 11.

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