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Items: 1 to 20 of 30


The anaphase-promoting complex/cyclosome activator Cdh1 modulates Rho GTPase by targeting p190 RhoGAP for degradation.

Naoe H, Araki K, Nagano O, Kobayashi Y, Ishizawa J, Chiyoda T, Shimizu T, Yamamura K, Sasaki Y, Saya H, Kuninaka S.

Mol Cell Biol. 2010 Aug;30(16):3994-4005. doi: 10.1128/MCB.01358-09. Epub 2010 Jun 7.


FGF-regulated BMP signaling is required for eyelid closure and to specify conjunctival epithelial cell fate.

Huang J, Dattilo LK, Rajagopal R, Liu Y, Kaartinen V, Mishina Y, Deng CX, Umans L, Zwijsen A, Roberts AB, Beebe DC.

Development. 2009 May;136(10):1741-50. doi: 10.1242/dev.034082. Epub 2009 Apr 15.


Differential requirement for MEK/ERK and SMAD signaling in PAI-1 and CTGF expression in response to microtubule disruption.

Samarakoon R, Higgins CE, Higgins SP, Higgins PJ.

Cell Signal. 2009 Jun;21(6):986-95. doi: 10.1016/j.cellsig.2009.02.007. Epub 2009 Feb 25.


Grainyhead-like factor Get1/Grhl3 regulates formation of the epidermal leading edge during eyelid closure.

Yu Z, Bhandari A, Mannik J, Pham T, Xu X, Andersen B.

Dev Biol. 2008 Jul 1;319(1):56-67. doi: 10.1016/j.ydbio.2008.04.001. Epub 2008 Apr 15.


The canonical Wnt signaling antagonist DKK2 is an essential effector of PITX2 function during normal eye development.

Gage PJ, Qian M, Wu D, Rosenberg KI.

Dev Biol. 2008 May 1;317(1):310-24. doi: 10.1016/j.ydbio.2008.02.030. Epub 2008 Mar 4.


Differential transmission of MEKK1 morphogenetic signals by JNK1 and JNK2.

Takatori A, Geh E, Chen L, Zhang L, Meller J, Xia Y.

Development. 2008 Jan;135(1):23-32. Epub 2007 Nov 21.


Exogenous FGF10 can rescue an eye-open at birth phenotype of Fgf10-null mice by activating activin and TGFalpha-EGFR signaling.

Tao H, Ono K, Kurose H, Noji S, Ohuchi H.

Dev Growth Differ. 2006 Jun;48(5):339-46.


HB-EGF promotes epithelial cell migration in eyelid development.

Mine N, Iwamoto R, Mekada E.

Development. 2005 Oct;132(19):4317-26. Epub 2005 Sep 1.


ROCK-I and ROCK-II cooperatively regulate closure of eyelid and ventral body wall in mouse embryo.

Thumkeo D, Shimizu Y, Sakamoto S, Yamada S, Narumiya S.

Genes Cells. 2005 Aug;10(8):825-34.


PAI-1 expression is required for epithelial cell migration in two distinct phases of in vitro wound repair.

Providence KM, Higgins PJ.

J Cell Physiol. 2004 Aug;200(2):297-308.


The control of cell motility and epithelial morphogenesis by Jun kinases.

Xia Y, Karin M.

Trends Cell Biol. 2004 Feb;14(2):94-101. Review.


The small GTP-binding protein RhoA regulates c-jun by a ROCK-JNK signaling axis.

Marinissen MJ, Chiariello M, Tanos T, Bernard O, Narumiya S, Gutkind JS.

Mol Cell. 2004 Apr 9;14(1):29-41.


Foxl2 disruption causes mouse ovarian failure by pervasive blockage of follicle development.

Uda M, Ottolenghi C, Crisponi L, Garcia JE, Deiana M, Kimber W, Forabosco A, Cao A, Schlessinger D, Pilia G.

Hum Mol Genet. 2004 Jun 1;13(11):1171-81. Epub 2004 Mar 31.


RhoA binds to the amino terminus of MEKK1 and regulates its kinase activity.

Gallagher ED, Gutowski S, Sternweis PC, Cobb MH.

J Biol Chem. 2004 Jan 16;279(3):1872-7. Epub 2003 Oct 27.


A role for MEK kinase 1 in TGF-beta/activin-induced epithelium movement and embryonic eyelid closure.

Zhang L, Wang W, Hayashi Y, Jester JV, Birk DE, Gao M, Liu CY, Kao WW, Karin M, Xia Y.

EMBO J. 2003 Sep 1;22(17):4443-54.


c-Jun regulates eyelid closure and skin tumor development through EGFR signaling.

Zenz R, Scheuch H, Martin P, Frank C, Eferl R, Kenner L, Sibilia M, Wagner EF.

Dev Cell. 2003 Jun;4(6):879-89.


c-Jun is essential for organization of the epidermal leading edge.

Li G, Gustafson-Brown C, Hanks SK, Nason K, Arbeit JM, Pogliano K, Wisdom RM, Johnson RS.

Dev Cell. 2003 Jun;4(6):865-77.


JNK initiates a cytokine cascade that causes Pax2 expression and closure of the optic fissure.

Weston CR, Wong A, Hall JP, Goad ME, Flavell RA, Davis RJ.

Genes Dev. 2003 May 15;17(10):1271-80.


MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation.

Yujiri T, Ware M, Widmann C, Oyer R, Russell D, Chan E, Zaitsu Y, Clarke P, Tyler K, Oka Y, Fanger GR, Henson P, Johnson GL.

Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):7272-7.

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