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Items: 1 to 20 of 62


Sequence specificity is obtained from the majority of modular C2H2 zinc-finger arrays.

Lam KN, van Bakel H, Cote AG, van der Ven A, Hughes TR.

Nucleic Acids Res. 2011 Jun;39(11):4680-90. doi: 10.1093/nar/gkq1303. Epub 2011 Feb 14.


Preassembled zinc-finger arrays for rapid construction of ZFNs.

Kim S, Lee MJ, Kim H, Kang M, Kim JS.

Nat Methods. 2011 Jan;8(1):7. doi: 10.1038/nmeth0111-7a. No abstract available.


Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA).

Sander JD, Dahlborg EJ, Goodwin MJ, Cade L, Zhang F, Cifuentes D, Curtin SJ, Blackburn JS, Thibodeau-Beganny S, Qi Y, Pierick CJ, Hoffman E, Maeder ML, Khayter C, Reyon D, Dobbs D, Langenau DM, Stupar RM, Giraldez AJ, Voytas DF, Peterson RT, Yeh JR, Joung JK.

Nat Methods. 2011 Jan;8(1):67-9. doi: 10.1038/nmeth.1542. Epub 2010 Dec 12.


Targeted integration in rat and mouse embryos with zinc-finger nucleases.

Cui X, Ji D, Fisher DA, Wu Y, Briner DM, Weinstein EJ.

Nat Biotechnol. 2011 Jan;29(1):64-7. doi: 10.1038/nbt.1731. Epub 2010 Dec 12.


Oligodendrocyte progenitor cell numbers and migration are regulated by the zebrafish orthologs of the NF1 tumor suppressor gene.

Lee JS, Padmanabhan A, Shin J, Zhu S, Guo F, Kanki JP, Epstein JA, Look AT.

Hum Mol Genet. 2010 Dec 1;19(23):4643-53. doi: 10.1093/hmg/ddq395. Epub 2010 Sep 21.


Zinc finger protein-dependent and -independent contributions to the in vivo off-target activity of zinc finger nucleases.

Gupta A, Meng X, Zhu LJ, Lawson ND, Wolfe SA.

Nucleic Acids Res. 2011 Jan;39(1):381-92. doi: 10.1093/nar/gkq787. Epub 2010 Sep 14.


Genome editing with engineered zinc finger nucleases.

Urnov FD, Rebar EJ, Holmes MC, Zhang HS, Gregory PD.

Nat Rev Genet. 2010 Sep;11(9):636-46. doi: 10.1038/nrg2842. Review.


Targeted mutagenesis in the silkworm Bombyx mori using zinc finger nuclease mRNA injection.

Takasu Y, Kobayashi I, Beumer K, Uchino K, Sezutsu H, Sajwan S, Carroll D, Tamura T, Zurovec M.

Insect Biochem Mol Biol. 2010 Oct;40(10):759-65. doi: 10.1016/j.ibmb.2010.07.012. Epub 2010 Aug 6.


Gene targeting by homologous recombination in mouse zygotes mediated by zinc-finger nucleases.

Meyer M, de Angelis MH, Wurst W, Kühn R.

Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15022-6. doi: 10.1073/pnas.1009424107. Epub 2010 Aug 4.


Construction of combinatorial libraries that encode zinc finger-based transcription factors.

Kim S, Kim EJ, Kim JS.

Methods Mol Biol. 2010;649:133-47. doi: 10.1007/978-1-60761-753-2_8.


A novel miRNA processing pathway independent of Dicer requires Argonaute2 catalytic activity.

Cifuentes D, Xue H, Taylor DW, Patnode H, Mishima Y, Cheloufi S, Ma E, Mane S, Hannon GJ, Lawson ND, Wolfe SA, Giraldez AJ.

Science. 2010 Jun 25;328(5986):1694-8. doi: 10.1126/science.1190809. Epub 2010 May 6.


Generation of knockout rats with X-linked severe combined immunodeficiency (X-SCID) using zinc-finger nucleases.

Mashimo T, Takizawa A, Voigt B, Yoshimi K, Hiai H, Kuramoto T, Serikawa T.

PLoS One. 2010 Jan 25;5(1):e8870. doi: 10.1371/journal.pone.0008870.


Cardiac and vascular functions of the zebrafish orthologues of the type I neurofibromatosis gene NFI.

Padmanabhan A, Lee JS, Ismat FA, Lu MM, Lawson ND, Kanki JP, Look AT, Epstein JA.

Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22305-10. doi: 10.1073/pnas.0901932106. Epub 2009 Dec 4.


Chemokine signaling guides regional patterning of the first embryonic artery.

Siekmann AF, Standley C, Fogarty KE, Wolfe SA, Lawson ND.

Genes Dev. 2009 Oct 1;23(19):2272-7. doi: 10.1101/gad.1813509.


Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases.

Hockemeyer D, Soldner F, Beard C, Gao Q, Mitalipova M, DeKelver RC, Katibah GE, Amora R, Boydston EA, Zeitler B, Meng X, Miller JC, Zhang L, Rebar EJ, Gregory PD, Urnov FD, Jaenisch R.

Nat Biotechnol. 2009 Sep;27(9):851-7. doi: 10.1038/nbt.1562. Epub 2009 Aug 13.


Knockout rats via embryo microinjection of zinc-finger nucleases.

Geurts AM, Cost GJ, Freyvert Y, Zeitler B, Miller JC, Choi VM, Jenkins SS, Wood A, Cui X, Meng X, Vincent A, Lam S, Michalkiewicz M, Schilling R, Foeckler J, Kalloway S, Weiler H, Ménoret S, Anegon I, Davis GD, Zhang L, Rebar EJ, Gregory PD, Urnov FD, Jacob HJ, Buelow R.

Science. 2009 Jul 24;325(5939):433. doi: 10.1126/science.1172447.


Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly.

Kim HJ, Lee HJ, Kim H, Cho SW, Kim JS.

Genome Res. 2009 Jul;19(7):1279-88. doi: 10.1101/gr.089417.108. Epub 2009 May 21.


A mechanosensitive transcriptional mechanism that controls angiogenesis.

Mammoto A, Connor KM, Mammoto T, Yung CW, Huh D, Aderman CM, Mostoslavsky G, Smith LE, Ingber DE.

Nature. 2009 Feb 26;457(7233):1103-8. doi: 10.1038/nature07765.


Rapid mutation of endogenous zebrafish genes using zinc finger nucleases made by Oligomerized Pool ENgineering (OPEN).

Foley JE, Yeh JR, Maeder ML, Reyon D, Sander JD, Peterson RT, Joung JK.

PLoS One. 2009;4(2):e4348. doi: 10.1371/journal.pone.0004348. Epub 2009 Feb 9.


Efficient gene targeting in Drosophila by direct embryo injection with zinc-finger nucleases.

Beumer KJ, Trautman JK, Bozas A, Liu JL, Rutter J, Gall JG, Carroll D.

Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19821-6. doi: 10.1073/pnas.0810475105. Epub 2008 Dec 8.

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