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Items: 1 to 20 of 34

1.

Actions of a picomolar short-acting S1P₁ agonist in S1P₁-eGFP knock-in mice.

Cahalan SM, Gonzalez-Cabrera PJ, Sarkisyan G, Nguyen N, Schaeffer MT, Huang L, Yeager A, Clemons B, Scott F, Rosen H.

Nat Chem Biol. 2011 May;7(5):254-6. doi: 10.1038/nchembio.547. Epub 2011 Mar 27.

2.

Virulence determinants of pandemic influenza viruses.

Tscherne DM, García-Sastre A.

J Clin Invest. 2011 Jan;121(1):6-13. doi: 10.1172/JCI44947. Epub 2011 Jan 4. Review.

3.

Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis.

Brinkmann V, Billich A, Baumruker T, Heining P, Schmouder R, Francis G, Aradhye S, Burtin P.

Nat Rev Drug Discov. 2010 Nov;9(11):883-97. doi: 10.1038/nrd3248. Epub 2010 Oct 29. Review.

PMID:
21031003
4.

Cytokine-dependent but acquired immunity-independent arthritis caused by DNA escaped from degradation.

Kawane K, Tanaka H, Kitahara Y, Shimaoka S, Nagata S.

Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19432-7. doi: 10.1073/pnas.1010603107. Epub 2010 Oct 25.

5.

Influenza vaccination: lessons learned from the pandemic (H1N1) 2009 influenza outbreak.

Openshaw PJ, Dunning J.

Mucosal Immunol. 2010 Sep;3(5):422-4. doi: 10.1038/mi.2010.34. Epub 2010 Jun 16. No abstract available.

PMID:
20555316
6.

Influenza virus receptor specificity: disease and transmission.

García-Sastre A.

Am J Pathol. 2010 Apr;176(4):1584-5. doi: 10.2353/ajpath.2010.100066. Epub 2010 Mar 4. No abstract available.

7.

Th1 and Th17 hypercytokinemia as early host response signature in severe pandemic influenza.

Bermejo-Martin JF, Ortiz de Lejarazu R, Pumarola T, Rello J, Almansa R, Ramírez P, Martin-Loeches I, Varillas D, Gallegos MC, Serón C, Micheloud D, Gomez JM, Tenorio-Abreu A, Ramos MJ, Molina ML, Huidobro S, Sanchez E, Gordón M, Fernández V, Del Castillo A, Marcos MA, Villanueva B, López CJ, Rodríguez-Domínguez M, Galan JC, Cantón R, Lietor A, Rojo S, Eiros JM, Hinojosa C, Gonzalez I, Torner N, Banner D, Leon A, Cuesta P, Rowe T, Kelvin DJ.

Crit Care. 2009;13(6):R201. doi: 10.1186/cc8208. Epub 2009 Dec 11.

8.

Lethal influenza virus infection in macaques is associated with early dysregulation of inflammatory related genes.

Cillóniz C, Shinya K, Peng X, Korth MJ, Proll SC, Aicher LD, Carter VS, Chang JH, Kobasa D, Feldmann F, Strong JE, Feldmann H, Kawaoka Y, Katze MG.

PLoS Pathog. 2009 Oct;5(10):e1000604. doi: 10.1371/journal.ppat.1000604. Epub 2009 Oct 2.

9.

In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses.

Itoh Y, Shinya K, Kiso M, Watanabe T, Sakoda Y, Hatta M, Muramoto Y, Tamura D, Sakai-Tagawa Y, Noda T, Sakabe S, Imai M, Hatta Y, Watanabe S, Li C, Yamada S, Fujii K, Murakami S, Imai H, Kakugawa S, Ito M, Takano R, Iwatsuki-Horimoto K, Shimojima M, Horimoto T, Goto H, Takahashi K, Makino A, Ishigaki H, Nakayama M, Okamatsu M, Takahashi K, Warshauer D, Shult PA, Saito R, Suzuki H, Furuta Y, Yamashita M, Mitamura K, Nakano K, Nakamura M, Brockman-Schneider R, Mitamura H, Yamazaki M, Sugaya N, Suresh M, Ozawa M, Neumann G, Gern J, Kida H, Ogasawara K, Kawaoka Y.

Nature. 2009 Aug 20;460(7258):1021-5. doi: 10.1038/nature08260.

10.

Sphingosine 1-phosphate receptor signaling.

Rosen H, Gonzalez-Cabrera PJ, Sanna MG, Brown S.

Annu Rev Biochem. 2009;78:743-68. doi: 10.1146/annurev.biochem.78.072407.103733. Review.

PMID:
19231986
11.

Induction of a striking systemic cytokine cascade prior to peak viremia in acute human immunodeficiency virus type 1 infection, in contrast to more modest and delayed responses in acute hepatitis B and C virus infections.

Stacey AR, Norris PJ, Qin L, Haygreen EA, Taylor E, Heitman J, Lebedeva M, DeCamp A, Li D, Grove D, Self SG, Borrow P.

J Virol. 2009 Apr;83(8):3719-33. doi: 10.1128/JVI.01844-08. Epub 2009 Jan 28.

12.

A critical role for the sphingosine analog AAL-R in dampening the cytokine response during influenza virus infection.

Marsolais D, Hahm B, Walsh KB, Edelmann KH, McGavern D, Hatta Y, Kawaoka Y, Rosen H, Oldstone MB.

Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1560-5. doi: 10.1073/pnas.0812689106. Epub 2009 Jan 21.

13.

The alliance of sphingosine-1-phosphate and its receptors in immunity.

Rivera J, Proia RL, Olivera A.

Nat Rev Immunol. 2008 Oct;8(10):753-63. doi: 10.1038/nri2400. Review.

14.

Full pharmacological efficacy of a novel S1P1 agonist that does not require S1P-like headgroup interactions.

Gonzalez-Cabrera PJ, Jo E, Sanna MG, Brown S, Leaf N, Marsolais D, Schaeffer MT, Chapman J, Cameron M, Guerrero M, Roberts E, Rosen H.

Mol Pharmacol. 2008 Nov;74(5):1308-18. doi: 10.1124/mol.108.049783. Epub 2008 Aug 15.

15.

Modulating tone: the overture of S1P receptor immunotherapeutics.

Rosen H, Gonzalez-Cabrera P, Marsolais D, Cahalan S, Don AS, Sanna MG.

Immunol Rev. 2008 Jun;223:221-35. doi: 10.1111/j.1600-065X.2008.00645.x. Review.

PMID:
18613839
16.

Local not systemic modulation of dendritic cell S1P receptors in lung blunts virus-specific immune responses to influenza.

Marsolais D, Hahm B, Edelmann KH, Walsh KB, Guerrero M, Hatta Y, Kawaoka Y, Roberts E, Oldstone MB, Rosen H.

Mol Pharmacol. 2008 Sep;74(3):896-903. doi: 10.1124/mol.108.048769. Epub 2008 Jun 24.

17.

Interferon and cytokine responses to SARS-coronavirus infection.

Thiel V, Weber F.

Cytokine Growth Factor Rev. 2008 Apr;19(2):121-32. doi: 10.1016/j.cytogfr.2008.01.001. Epub 2008 Mar 5. Review.

PMID:
18321765
18.

Tipping the gatekeeper: S1P regulation of endothelial barrier function.

Rosen H, Sanna MG, Cahalan SM, Gonzalez-Cabrera PJ.

Trends Immunol. 2007 Mar;28(3):102-7. Epub 2007 Feb 5. Review.

PMID:
17276731
19.

Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus.

Kobasa D, Jones SM, Shinya K, Kash JC, Copps J, Ebihara H, Hatta Y, Kim JH, Halfmann P, Hatta M, Feldmann F, Alimonti JB, Fernando L, Li Y, Katze MG, Feldmann H, Kawaoka Y.

Nature. 2007 Jan 18;445(7125):319-23.

PMID:
17230189
20.

A question of self-preservation: immunopathology in influenza virus infection.

La Gruta NL, Kedzierska K, Stambas J, Doherty PC.

Immunol Cell Biol. 2007 Feb-Mar;85(2):85-92. Epub 2007 Jan 9. Review.

PMID:
17213831

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