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Items: 1 to 20 of 39


New therapies for asthma: is there any progress?

Barnes PJ.

Trends Pharmacol Sci. 2010 Jul;31(7):335-43. doi: 10.1016/ Review.


Regulatory T cells in many flavors control asthma.

Ray A, Khare A, Krishnamoorthy N, Qi Z, Ray P.

Mucosal Immunol. 2010 May;3(3):216-29. doi: 10.1038/mi.2010.4. Review.


CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner.

Chaudhry A, Rudra D, Treuting P, Samstein RM, Liang Y, Kas A, Rudensky AY.

Science. 2009 Nov 13;326(5955):986-91. doi: 10.1126/science.1172702.


Differential effect of IL-27 on developing versus committed Th17 cells.

El-behi M, Ciric B, Yu S, Zhang GX, Fitzgerald DC, Rostami A.

J Immunol. 2009 Oct 15;183(8):4957-67. doi: 10.4049/jimmunol.0900735.


Regulatory T cells in asthma.

Lloyd CM, Hawrylowicz CM.

Immunity. 2009 Sep 18;31(3):438-49. doi: 10.1016/j.immuni.2009.08.007. Review.


Allergic sensitization through the airway primes Th17-dependent neutrophilia and airway hyperresponsiveness.

Wilson RH, Whitehead GS, Nakano H, Free ME, Kolls JK, Cook DN.

Am J Respir Crit Care Med. 2009 Oct 15;180(8):720-30. doi: 10.1164/rccm.200904-0573OC.


Airway remodeling in subjects with severe asthma with or without chronic persistent airflow obstruction.

Kaminska M, Foley S, Maghni K, Storness-Bliss C, Coxson H, Ghezzo H, Lemière C, Olivenstein R, Ernst P, Hamid Q, Martin J.

J Allergy Clin Immunol. 2009 Jul;124(1):45-51.e1-4. doi: 10.1016/j.jaci.2009.03.049.


Impaired CD4 and CD8 effector function and decreased memory T cell populations in ICOS-deficient patients.

Takahashi N, Matsumoto K, Saito H, Nanki T, Miyasaka N, Kobata T, Azuma M, Lee SK, Mizutani S, Morio T.

J Immunol. 2009 May 1;182(9):5515-27. doi: 10.4049/jimmunol.0803256.


IL-10 interferes directly with TCR-induced IFN-gamma but not IL-17 production in memory T cells.

Naundorf S, Schröder M, Höflich C, Suman N, Volk HD, Grütz G.

Eur J Immunol. 2009 Apr;39(4):1066-77. doi: 10.1002/eji.200838773. Erratum in: Eur J Immunol. 2009 May;39(5):1435.


IL-17-producing alveolar macrophages mediate allergic lung inflammation related to asthma.

Song C, Luo L, Lei Z, Li B, Liang Z, Liu G, Li D, Zhang G, Huang B, Feng ZH.

J Immunol. 2008 Nov 1;181(9):6117-24.


IL-23 and Th17 cells enhance Th2-cell-mediated eosinophilic airway inflammation in mice.

Wakashin H, Hirose K, Maezawa Y, Kagami S, Suto A, Watanabe N, Saito Y, Hatano M, Tokuhisa T, Iwakura Y, Puccetti P, Iwamoto I, Nakajima H.

Am J Respir Crit Care Med. 2008 Nov 15;178(10):1023-32. doi: 10.1164/rccm.200801-086OC.


TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice.

McKinley L, Alcorn JF, Peterson A, Dupont RB, Kapadia S, Logar A, Henry A, Irvin CG, Piganelli JD, Ray A, Kolls JK.

J Immunol. 2008 Sep 15;181(6):4089-97.


Two functional subsets of FOXP3+ regulatory T cells in human thymus and periphery.

Ito T, Hanabuchi S, Wang YH, Park WR, Arima K, Bover L, Qin FX, Gilliet M, Liu YJ.

Immunity. 2008 Jun;28(6):870-80. doi: 10.1016/j.immuni.2008.03.018.


Epstein-Barr virus-induced gene 3 negatively regulates IL-17, IL-22 and RORgamma t.

Yang J, Yang M, Htut TM, Ouyang X, Hanidu A, Li X, Sellati R, Jiang H, Zhang S, Li H, Zhao J, Ting AT, Mayer L, Unkeless JC, Labadia ME, Hodge M, Li J, Xiong H.

Eur J Immunol. 2008 May;38(5):1204-14. doi: 10.1002/eji.200838145.


Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces.

Rubtsov YP, Rasmussen JP, Chi EY, Fontenot J, Castelli L, Ye X, Treuting P, Siewe L, Roers A, Henderson WR Jr, Muller W, Rudensky AY.

Immunity. 2008 Apr;28(4):546-58. doi: 10.1016/j.immuni.2008.02.017.


The demise of anti IL-5 for asthma, or not.

O'Byrne PM.

Am J Respir Crit Care Med. 2007 Dec 1;176(11):1059-60. No abstract available.


The inhibitory cytokine IL-35 contributes to regulatory T-cell function.

Collison LW, Workman CJ, Kuo TT, Boyd K, Wang Y, Vignali KM, Cross R, Sehy D, Blumberg RS, Vignali DA.

Nature. 2007 Nov 22;450(7169):566-9.


How strong is the evidence that immunotherapy in children prevents the progression of allergy and asthma?

Jacobsen L, Valovirta E.

Curr Opin Allergy Clin Immunol. 2007 Dec;7(6):556-60. Review.


IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Th17 cells.

Niedbala W, Wei XQ, Cai B, Hueber AJ, Leung BP, McInnes IB, Liew FY.

Eur J Immunol. 2007 Nov;37(11):3021-9. Erratum in: Eur J Immunol. 2007 Nov;37(11):3293.


Naturally occurring lung CD4(+)CD25(+) T cell regulation of airway allergic responses depends on IL-10 induction of TGF-beta.

Joetham A, Takeda K, Taube C, Miyahara N, Matsubara S, Koya T, Rha YH, Dakhama A, Gelfand EW.

J Immunol. 2007 Feb 1;178(3):1433-42. Erratum in: J Immunol. 2007 Apr 15;178(8):5400. Takada, Katsuyuki [corrected to Takeda, Katsuyuki]; Matsubara, Satoko [corrected to Matsubara, Shigeki].

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