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Salmonella pathogenesis and processing of secreted effectors by caspase-3.

Srikanth CV, Wall DM, Maldonado-Contreras A, Shi H, Zhou D, Demma Z, Mumy KL, McCormick BA.

Science. 2010 Oct 15;330(6002):390-393. doi: 10.1126/science.1194598.


NHERF-1 binds to Mrp2 and regulates hepatic Mrp2 expression and function.

Li M, Wang W, Soroka CJ, Mennone A, Harry K, Weinman EJ, Boyer JL.

J Biol Chem. 2010 Jun 18;285(25):19299-307. doi: 10.1074/jbc.M109.096081. Epub 2010 Apr 19.


Correlation between apical localization of Abcc2/Mrp2 and phosphorylation status of ezrin in rat intestine.

Nakano T, Sekine S, Ito K, Horie T.

Drug Metab Dispos. 2009 Jul;37(7):1521-7. doi: 10.1124/dmd.108.024836. Epub 2009 Apr 1.


Multidrug resistance-associated transporter 2 regulates mucosal inflammation by facilitating the synthesis of hepoxilin A3.

Pazos M, Siccardi D, Mumy KL, Bien JD, Louie S, Shi HN, Gronert K, Mrsny RJ, McCormick BA.

J Immunol. 2008 Dec 1;181(11):8044-52.


Distinct isoforms of phospholipase A2 mediate the ability of Salmonella enterica serotype typhimurium and Shigella flexneri to induce the transepithelial migration of neutrophils.

Mumy KL, Bien JD, Pazos MA, Gronert K, Hurley BP, McCormick BA.

Infect Immun. 2008 Aug;76(8):3614-27. doi: 10.1128/IAI.00407-08. Epub 2008 May 27.


Salmonella enterica serovar Typhimurium modulates P-glycoprotein in the intestinal epithelium.

Siccardi D, Mumy KL, Wall DM, Bien JD, McCormick BA.

Am J Physiol Gastrointest Liver Physiol. 2008 Jun;294(6):G1392-400. doi: 10.1152/ajpgi.00599.2007. Epub 2008 Apr 10.


Atypical protein kinase C (iota) activates ezrin in the apical domain of intestinal epithelial cells.

Wald FA, Oriolo AS, Mashukova A, Fregien NL, Langshaw AH, Salas PJ.

J Cell Sci. 2008 Mar 1;121(Pt 5):644-54. doi: 10.1242/jcs.016246. Epub 2008 Feb 12.


Osmotic cell shrinkage activates ezrin/radixin/moesin (ERM) proteins: activation mechanisms and physiological implications.

Rasmussen M, Alexander RT, Darborg BV, Møbjerg N, Hoffmann EK, Kapus A, Pedersen SF.

Am J Physiol Cell Physiol. 2008 Jan;294(1):C197-212. Epub 2007 Oct 31.


Ezrin and radixin both regulate the apical membrane localization of ABCC2 (MRP2) in human intestinal epithelial Caco-2 cells.

Yang Q, Onuki R, Nakai C, Sugiyama Y.

Exp Cell Res. 2007 Oct 1;313(16):3517-25. Epub 2007 Aug 7.


Protein kinase C family: on the crossroads of cell signaling in skin and tumor epithelium.

Breitkreutz D, Braiman-Wiksman L, Daum N, Denning MF, Tennenbaum T.

J Cancer Res Clin Oncol. 2007 Nov;133(11):793-808. Epub 2007 Jul 28. Review.


Salmonella enterica serovar Typhimurium regulates intercellular junction proteins and facilitates transepithelial neutrophil and bacterial passage.

Köhler H, Sakaguchi T, Hurley BP, Kase BA, Reinecker HC, McCormick BA.

Am J Physiol Gastrointest Liver Physiol. 2007 Jul;293(1):G178-87. Erratum in: Am J Physiol Gastrointest Liver Physiol. 2007 Nov;293(5):G1099. Kase, Benjamin J [corrected to Kase, Benjamin A].


Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity.

Cummins EP, Berra E, Comerford KM, Ginouves A, Fitzgerald KT, Seeballuck F, Godson C, Nielsen JE, Moynagh P, Pouyssegur J, Taylor CT.

Proc Natl Acad Sci U S A. 2006 Nov 28;103(48):18154-9. Epub 2006 Nov 17.


Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes.

Wang W, Soroka CJ, Mennone A, Rahner C, Harry K, Pypaert M, Boyer JL.

Gastroenterology. 2006 Sep;131(3):878-84.


Mrp2/Abcc2 transport activity is stimulated by protein kinase Calpha in a baculo virus co-expression system.

Ito K, Wakabayashi T, Horie T.

Life Sci. 2005 Jun 17;77(5):539-50. Epub 2005 Feb 23.


Akt2 phosphorylates ezrin to trigger NHE3 translocation and activation.

Shiue H, Musch MW, Wang Y, Chang EB, Turner JR.

J Biol Chem. 2005 Jan 14;280(2):1688-95. Epub 2004 Nov 4.


Ezrin regulates NHE3 translocation and activation after Na+-glucose cotransport.

Zhao H, Shiue H, Palkon S, Wang Y, Cullinan P, Burkhardt JK, Musch MW, Chang EB, Turner JR.

Proc Natl Acad Sci U S A. 2004 Jun 22;101(25):9485-90. Epub 2004 Jun 14.


Identification of hepoxilin A3 in inflammatory events: a required role in neutrophil migration across intestinal epithelia.

Mrsny RJ, Gewirtz AT, Siccardi D, Savidge T, Hurley BP, Madara JL, McCormick BA.

Proc Natl Acad Sci U S A. 2004 May 11;101(19):7421-6. Epub 2004 May 3.


Salmonella typhimurium SipA-induced neutrophil transepithelial migration: involvement of a PKC-alpha-dependent signal transduction pathway.

Silva M, Song C, Nadeau WJ, Matthews JB, McCormick BA.

Am J Physiol Gastrointest Liver Physiol. 2004 Jun;286(6):G1024-31. Epub 2004 Jan 22.


Identification of a novel 2026G-->C mutation of the MRP2 gene in a Japanese patient with Dubin-Johnson syndrome.

Wakusawa S, Machida I, Suzuki S, Hayashi H, Yano M, Yoshioka K.

J Hum Genet. 2003;48(8):425-9. Epub 2003 Jul 22.


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