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Items: 1 to 20 of 61

1.

NF-κB inducing kinase: a key regulator in the immune system and in cancer.

Thu YM, Richmond A.

Cytokine Growth Factor Rev. 2010 Aug;21(4):213-26. doi: 10.1016/j.cytogfr.2010.06.002. Epub 2010 Aug 3. Review.

2.

Allosteric regulation of the ubiquitin:NIK and ubiquitin:TRAF3 E3 ligases by the lymphotoxin-beta receptor.

Sanjo H, Zajonc DM, Braden R, Norris PS, Ware CF.

J Biol Chem. 2010 May 28;285(22):17148-55. doi: 10.1074/jbc.M110.105874. Epub 2010 Mar 26.

3.

Ontogeny of stromal organizer cells during lymph node development.

Bénézech C, White A, Mader E, Serre K, Parnell S, Pfeffer K, Ware CF, Anderson G, Caamaño JH.

J Immunol. 2010 Apr 15;184(8):4521-30. doi: 10.4049/jimmunol.0903113. Epub 2010 Mar 17.

4.

TRAF3 controls activation of the canonical and alternative NFkappaB by the lymphotoxin beta receptor.

Bista P, Zeng W, Ryan S, Bailly V, Browning JL, Lukashev ME.

J Biol Chem. 2010 Apr 23;285(17):12971-8. doi: 10.1074/jbc.M109.076091. Epub 2010 Feb 25.

5.

Regulation of tissue homeostasis by NF-kappaB signalling: implications for inflammatory diseases.

Pasparakis M.

Nat Rev Immunol. 2009 Nov;9(11):778-88. doi: 10.1038/nri2655. Review.

PMID:
19855404
6.

A lymphotoxin-driven pathway to hepatocellular carcinoma.

Haybaeck J, Zeller N, Wolf MJ, Weber A, Wagner U, Kurrer MO, Bremer J, Iezzi G, Graf R, Clavien PA, Thimme R, Blum H, Nedospasov SA, Zatloukal K, Ramzan M, Ciesek S, Pietschmann T, Marche PN, Karin M, Kopf M, Browning JL, Aguzzi A, Heikenwalder M.

Cancer Cell. 2009 Oct 6;16(4):295-308. doi: 10.1016/j.ccr.2009.08.021. Erratum in: Cancer Cell. 2009 Nov 6;16(5):447.

7.

Regulation of TNFRSF and innate immune signalling complexes by TRAFs and cIAPs.

Silke J, Brink R.

Cell Death Differ. 2010 Jan;17(1):35-45. doi: 10.1038/cdd.2009.114. Review.

8.

Linear polyubiquitination: a new regulator of NF-kappaB activation.

Iwai K, Tokunaga F.

EMBO Rep. 2009 Jul;10(7):706-13. doi: 10.1038/embor.2009.144. Epub 2009 Jun 19. Review.

9.

Immune complex relay by subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation.

Phan TG, Green JA, Gray EE, Xu Y, Cyster JG.

Nat Immunol. 2009 Jul;10(7):786-93. doi: 10.1038/ni.1745. Epub 2009 Jun 7.

10.

Unconventional ligand activation of herpesvirus entry mediator signals cell survival.

Cheung TC, Steinberg MW, Oborne LM, Macauley MG, Fukuyama S, Sanjo H, D'Souza C, Norris PS, Pfeffer K, Murphy KM, Kronenberg M, Spear PG, Ware CF.

Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6244-9. doi: 10.1073/pnas.0902115106. Epub 2009 Mar 30. Erratum in: Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16535-6.

11.

Regulation and function of NF-kappaB transcription factors in the immune system.

Vallabhapurapu S, Karin M.

Annu Rev Immunol. 2009;27:693-733. doi: 10.1146/annurev.immunol.021908.132641. Review.

PMID:
19302050
12.

A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex.

Kelly BT, McCoy AJ, Späte K, Miller SE, Evans PR, Höning S, Owen DJ.

Nature. 2008 Dec 18;456(7224):976-79. doi: 10.1038/nature07422. No abstract available.

13.

Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.

Zarnegar BJ, Wang Y, Mahoney DJ, Dempsey PW, Cheung HH, He J, Shiba T, Yang X, Yeh WC, Mak TW, Korneluk RG, Cheng G.

Nat Immunol. 2008 Dec;9(12):1371-8. doi: 10.1038/ni.1676. Epub 2008 Nov 9.

14.

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling.

Vallabhapurapu S, Matsuzawa A, Zhang W, Tseng PH, Keats JJ, Wang H, Vignali DA, Bergsagel PL, Karin M.

Nat Immunol. 2008 Dec;9(12):1364-70. doi: 10.1038/ni.1678. Epub 2008 Nov 9.

15.

NIK overexpression amplifies, whereas ablation of its TRAF3-binding domain replaces BAFF:BAFF-R-mediated survival signals in B cells.

Sasaki Y, Calado DP, Derudder E, Zhang B, Shimizu Y, Mackay F, Nishikawa S, Rajewsky K, Schmidt-Supprian M.

Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10883-8. doi: 10.1073/pnas.0805186105. Epub 2008 Jul 28.

16.

Essential cytoplasmic translocation of a cytokine receptor-assembled signaling complex.

Matsuzawa A, Tseng PH, Vallabhapurapu S, Luo JL, Zhang W, Wang H, Vignali DA, Gallagher E, Karin M.

Science. 2008 Aug 1;321(5889):663-8. doi: 10.1126/science.1157340. Epub 2008 Jul 17.

17.

Regulation of TNFR1 and CD95 signalling by receptor compartmentalization.

Schütze S, Tchikov V, Schneider-Brachert W.

Nat Rev Mol Cell Biol. 2008 Aug;9(8):655-62. doi: 10.1038/nrm2430. Epub 2008 Jun 11. Review.

PMID:
18545270
18.

The lymphotoxin-beta receptor is an upstream activator of NF-kappaB-mediated transcription in melanoma cells.

Dhawan P, Su Y, Thu YM, Yu Y, Baugher P, Ellis DL, Sobolik-Delmaire T, Kelley M, Cheung TC, Ware CF, Richmond A.

J Biol Chem. 2008 May 30;283(22):15399-408. doi: 10.1074/jbc.M708272200. Epub 2008 Mar 17.

19.

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta.

Kagan JC, Su T, Horng T, Chow A, Akira S, Medzhitov R.

Nat Immunol. 2008 Apr;9(4):361-8. doi: 10.1038/ni1569. Epub 2008 Feb 24.

20.

Control of canonical NF-kappaB activation through the NIK-IKK complex pathway.

Zarnegar B, Yamazaki S, He JQ, Cheng G.

Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3503-8. doi: 10.1073/pnas.0707959105. Epub 2008 Feb 21.

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