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Items: 1 to 20 of 226


The Dbp5 cycle at the nuclear pore complex during mRNA export II: nucleotide cycling and mRNP remodeling by Dbp5 are controlled by Nup159 and Gle1.

Noble KN, Tran EJ, Alcázar-Román AR, Hodge CA, Cole CN, Wente SR.

Genes Dev. 2011 May 15;25(10):1065-77. doi: 10.1101/gad.2040611.


Gcn4 misregulation reveals a direct role for the evolutionary conserved EKC/KEOPS in the t6A modification of tRNAs.

Daugeron MC, Lenstra TL, Frizzarin M, El Yacoubi B, Liu X, Baudin-Baillieu A, Lijnzaad P, Decourty L, Saveanu C, Jacquier A, Holstege FC, de Crécy-Lagard V, van Tilbeurgh H, Libri D.

Nucleic Acids Res. 2011 Aug;39(14):6148-60. doi: 10.1093/nar/gkr178. Epub 2011 Apr 1.


A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP6 in mRNA export.

Montpetit B, Thomsen ND, Helmke KJ, Seeliger MA, Berger JM, Weis K.

Nature. 2011 Apr 14;472(7342):238-42. doi: 10.1038/nature09862. Epub 2011 Mar 27.


mRNA helicases: the tacticians of translational control.

Parsyan A, Svitkin Y, Shahbazian D, Gkogkas C, Lasko P, Merrick WC, Sonenberg N.

Nat Rev Mol Cell Biol. 2011 Apr;12(4):235-45. doi: 10.1038/nrm3083. Review.


Common conformational changes induced in type 2 picornavirus IRESs by cognate trans-acting factors.

Yu Y, Abaeva IS, Marintchev A, Pestova TV, Hellen CU.

Nucleic Acids Res. 2011 Jun;39(11):4851-65. doi: 10.1093/nar/gkr045. Epub 2011 Feb 8.


A role for the universal Kae1/Qri7/YgjD (COG0533) family in tRNA modification.

El Yacoubi B, Hatin I, Deutsch C, Kahveci T, Rousset JP, Iwata-Reuyl D, Murzin AG, de Crécy-Lagard V.

EMBO J. 2011 Mar 2;30(5):882-93. doi: 10.1038/emboj.2010.363. Epub 2011 Feb 1.


Depletion of eIF4G from yeast cells narrows the range of translational efficiencies genome-wide.

Park EH, Zhang F, Warringer J, Sunnerhagen P, Hinnebusch AG.

BMC Genomics. 2011 Jan 26;12:68. doi: 10.1186/1471-2164-12-68.


An upstream ORF with non-AUG start codon is translated in vivo but dispensable for translational control of GCN4 mRNA.

Zhang F, Hinnebusch AG.

Nucleic Acids Res. 2011 Apr;39(8):3128-40. doi: 10.1093/nar/gkq1251. Epub 2011 Jan 11.


Crystal structure of the eukaryotic 40S ribosomal subunit in complex with initiation factor 1.

Rabl J, Leibundgut M, Ataide SF, Haag A, Ban N.

Science. 2011 Feb 11;331(6018):730-6. doi: 10.1126/science.1198308. Epub 2010 Dec 23.


The highly conserved KEOPS/EKC complex is essential for a universal tRNA modification, t6A.

Srinivasan M, Mehta P, Yu Y, Prugar E, Koonin EV, Karzai AW, Sternglanz R.

EMBO J. 2011 Mar 2;30(5):873-81. doi: 10.1038/emboj.2010.343. Epub 2010 Dec 24.


Multiple elements in the eIF4G1 N-terminus promote assembly of eIF4G1•PABP mRNPs in vivo.

Park EH, Walker SE, Lee JM, Rothenburg S, Lorsch JR, Hinnebusch AG.

EMBO J. 2011 Jan 19;30(2):302-16. doi: 10.1038/emboj.2010.312. Epub 2010 Dec 7.


Bypassing of stems versus linear base-by-base inspection of mammalian mRNAs during ribosomal scanning.

Abaeva IS, Marintchev A, Pisareva VP, Hellen CU, Pestova TV.

EMBO J. 2011 Jan 5;30(1):115-29. doi: 10.1038/emboj.2010.302. Epub 2010 Nov 26.


Synergistic activation of eIF4A by eIF4B and eIF4G.

Nielsen KH, Behrens MA, He Y, Oliveira CL, Jensen LS, Hoffmann SV, Pedersen JS, Andersen GR.

Nucleic Acids Res. 2011 Apr;39(7):2678-89. doi: 10.1093/nar/gkq1206. Epub 2010 Nov 26.


Crystal structure of the eukaryotic ribosome.

Ben-Shem A, Jenner L, Yusupova G, Yusupov M.

Science. 2010 Nov 26;330(6008):1203-9. doi: 10.1126/science.1194294.


eIF4G stimulates the activity of the DEAD box protein eIF4A by a conformational guidance mechanism.

Hilbert M, Kebbel F, Gubaev A, Klostermeier D.

Nucleic Acids Res. 2011 Mar;39(6):2260-70. doi: 10.1093/nar/gkq1127. Epub 2010 Nov 9.


Initiation context modulates autoregulation of eukaryotic translation initiation factor 1 (eIF1).

Ivanov IP, Loughran G, Sachs MS, Atkins JF.

Proc Natl Acad Sci U S A. 2010 Oct 19;107(42):18056-60. doi: 10.1073/pnas.1009269107. Epub 2010 Oct 4.


The 5'-7-methylguanosine cap on eukaryotic mRNAs serves both to stimulate canonical translation initiation and to block an alternative pathway.

Mitchell SF, Walker SE, Algire MA, Park EH, Hinnebusch AG, Lorsch JR.

Mol Cell. 2010 Sep 24;39(6):950-62. doi: 10.1016/j.molcel.2010.08.021.


tRNA binding properties of eukaryotic translation initiation factor 2 from Encephalitozoon cuniculi.

Naveau M, Lazennec-Schurdevin C, Panvert M, Mechulam Y, Schmitt E.

Biochemistry. 2010 Oct 12;49(40):8680-8. doi: 10.1021/bi1009166. Epub 2010 Sep 15.


Yeast 18 S rRNA is directly involved in the ribosomal response to stringent AUG selection during translation initiation.

Nemoto N, Singh CR, Udagawa T, Wang S, Thorson E, Winter Z, Ohira T, Ii M, Valásek L, Brown SJ, Asano K.

J Biol Chem. 2010 Oct 15;285(42):32200-12. doi: 10.1074/jbc.M110.146662. Epub 2010 Aug 10.


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