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Items: 1 to 20 of 44


Ion channel voltage sensors: structure, function, and pathophysiology.

Catterall WA.

Neuron. 2010 Sep 23;67(6):915-28. doi: 10.1016/j.neuron.2010.08.021. Review.


Targeting voltage sensors in sodium channels with spider toxins.

Bosmans F, Swartz KJ.

Trends Pharmacol Sci. 2010 Apr;31(4):175-82. doi: 10.1016/ Epub 2010 Jan 25. Review.


Molecular requirements for recognition of brain voltage-gated sodium channels by scorpion alpha-toxins.

Kahn R, Karbat I, Ilan N, Cohen L, Sokolov S, Catterall WA, Gordon D, Gurevitz M.

J Biol Chem. 2009 Jul 31;284(31):20684-91. doi: 10.1074/jbc.M109.021303. Epub 2009 Jun 9.


Deconstructing voltage sensor function and pharmacology in sodium channels.

Bosmans F, Martin-Eauclaire MF, Swartz KJ.

Nature. 2008 Nov 13;456(7219):202-8. doi: 10.1038/nature07473.


Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment.

Long SB, Tao X, Campbell EB, MacKinnon R.

Nature. 2007 Nov 15;450(7168):376-82.


Sites and molecular mechanisms of modulation of Na(v)1.2 channels by Fyn tyrosine kinase.

Beacham D, Ahn M, Catterall WA, Scheuer T.

J Neurosci. 2007 Oct 24;27(43):11543-51.


Closing in on the resting state of the Shaker K(+) channel.

Pathak MM, Yarov-Yarovoy V, Agarwal G, Roux B, Barth P, Kohout S, Tombola F, Isacoff EY.

Neuron. 2007 Oct 4;56(1):124-40.


Protein-protein docking with backbone flexibility.

Wang C, Bradley P, Baker D.

J Mol Biol. 2007 Oct 19;373(2):503-19. Epub 2007 Aug 2.


The unique pharmacology of the scorpion alpha-like toxin Lqh3 is associated with its flexible C-tail.

Karbat I, Kahn R, Cohen L, Ilan N, Gilles N, Corzo G, Froy O, Gur M, Albrecht G, Heinemann SH, Gordon D, Gurevitz M.

FEBS J. 2007 Apr;274(8):1918-31. Epub 2007 Mar 9.


Voltage-gated ion channels and gating modifier toxins.

Catterall WA, Cestèle S, Yarov-Yarovoy V, Yu FH, Konoki K, Scheuer T.

Toxicon. 2007 Feb;49(2):124-41. Epub 2006 Sep 28. Review.


Structure and function of the voltage sensor of sodium channels probed by a beta-scorpion toxin.

Cestèle S, Yarov-Yarovoy V, Qu Y, Sampieri F, Scheuer T, Catterall WA.

J Biol Chem. 2006 Jul 28;281(30):21332-44. Epub 2006 May 4.


Voltage sensor conformations in the open and closed states in ROSETTA structural models of K(+) channels.

Yarov-Yarovoy V, Baker D, Catterall WA.

Proc Natl Acad Sci U S A. 2006 May 9;103(19):7292-7. Epub 2006 Apr 28.


Subtype specificity of scorpion beta-toxin Tz1 interaction with voltage-gated sodium channels is determined by the pore loop of domain 3.

Leipold E, Hansel A, Borges A, Heinemann SH.

Mol Pharmacol. 2006 Jul;70(1):340-7. Epub 2006 Apr 25.


Multipass membrane protein structure prediction using Rosetta.

Yarov-Yarovoy V, Schonbrun J, Baker D.

Proteins. 2006 Mar 1;62(4):1010-25.


Crystal structure of a mammalian voltage-dependent Shaker family K+ channel.

Long SB, Campbell EB, Mackinnon R.

Science. 2005 Aug 5;309(5736):897-903. Epub 2005 Jul 7.


Voltage sensor of Kv1.2: structural basis of electromechanical coupling.

Long SB, Campbell EB, Mackinnon R.

Science. 2005 Aug 5;309(5736):903-8. Epub 2005 Jul 7.


UCSF Chimera--a visualization system for exploratory research and analysis.

Pettersen EF, Goddard TD, Huang CC, Couch GS, Greenblatt DM, Meng EC, Ferrin TE.

J Comput Chem. 2004 Oct;25(13):1605-12.


Molecular basis of the high insecticidal potency of scorpion alpha-toxins.

Karbat I, Frolow F, Froy O, Gilles N, Cohen L, Turkov M, Gordon D, Gurevitz M.

J Biol Chem. 2004 Jul 23;279(30):31679-86. Epub 2004 May 8.


Protein structure prediction using Rosetta.

Rohl CA, Strauss CE, Misura KM, Baker D.

Methods Enzymol. 2004;383:66-93. No abstract available.


Combinatorial interaction of scorpion toxins Lqh-2, Lqh-3, and LqhalphaIT with sodium channel receptor sites-3.

Leipold E, Lu S, Gordon D, Hansel A, Heinemann SH.

Mol Pharmacol. 2004 Mar;65(3):685-91.

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