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Items: 1 to 20 of 31

1.

Directed evolution of hydrolases for prevention of G-type nerve agent intoxication.

Gupta RD, Goldsmith M, Ashani Y, Simo Y, Mullokandov G, Bar H, Ben-David M, Leader H, Margalit R, Silman I, Sussman JL, Tawfik DS.

Nat Chem Biol. 2011 Feb;7(2):120-5. doi: 10.1038/nchembio.510. Epub 2011 Jan 9.

PMID:
21217689
2.

Phosphotriesterase variants with high methylphosphonatase activity and strong negative trade-off against phosphotriesters.

Briseño-Roa L, Timperley CM, Griffiths AD, Fersht AR.

Protein Eng Des Sel. 2011 Jan;24(1-2):151-9. doi: 10.1093/protein/gzq076. Epub 2010 Oct 30.

PMID:
21037279
3.

A murine model for sarin exposure using the carboxylesterase inhibitor CBDP.

Garrett TL, Rapp CM, Grubbs RD, Schlager JJ, Lucot JB.

Neurotoxicology. 2010 Sep;31(5):502-8. doi: 10.1016/j.neuro.2010.05.007. Epub 2010 May 25.

PMID:
20510297
4.

Engineering the mouse genome to model human disease for drug discovery.

Koentgen F, Suess G, Naf D.

Methods Mol Biol. 2010;602:55-77. doi: 10.1007/978-1-60761-058-8_4.

PMID:
20012392
5.

Pseudo-esterase activity of human albumin: slow turnover on tyrosine 411 and stable acetylation of 82 residues including 59 lysines.

Lockridge O, Xue W, Gaydess A, Grigoryan H, Ding SJ, Schopfer LM, Hinrichs SH, Masson P.

J Biol Chem. 2008 Aug 15;283(33):22582-90. doi: 10.1074/jbc.M802555200. Epub 2008 Jun 24.

6.

Inhibitory potency against human acetylcholinesterase and enzymatic hydrolysis of fluorogenic nerve agent mimics by human paraoxonase 1 and squid diisopropyl fluorophosphatase.

Blum MM, Timperley CM, Williams GR, Thiermann H, Worek F.

Biochemistry. 2008 May 6;47(18):5216-24. doi: 10.1021/bi702222x. Epub 2008 Apr 9.

PMID:
18396898
7.

Structure, function and regulation of carboxylesterases.

Satoh T, Hosokawa M.

Chem Biol Interact. 2006 Sep 25;162(3):195-211. Epub 2006 Jul 6. Review.

PMID:
16919614
8.

Comparison of polyethylene glycol-conjugated recombinant human acetylcholinesterase and serum human butyrylcholinesterase as bioscavengers of organophosphate compounds.

Cohen O, Kronman C, Raveh L, Mazor O, Ordentlich A, Shafferman A.

Mol Pharmacol. 2006 Sep;70(3):1121-31. Epub 2006 Jun 26.

9.

Analogues with fluorescent leaving groups for screening and selection of enzymes that efficiently hydrolyze organophosphorus nerve agents.

Briseño-Roa L, Hill J, Notman S, Sellers D, Smith AP, Timperley CM, Wetherell J, Williams NH, Williams GR, Fersht AR, Griffiths AD.

J Med Chem. 2006 Jan 12;49(1):246-55.

PMID:
16392809
10.

Butyrylcholinesterase, paraoxonase, and albumin esterase, but not carboxylesterase, are present in human plasma.

Li B, Sedlacek M, Manoharan I, Boopathy R, Duysen EG, Masson P, Lockridge O.

Biochem Pharmacol. 2005 Nov 25;70(11):1673-84. Epub 2005 Oct 6.

PMID:
16213467
11.

Potentiation and neurotoxicity induced by certain organophosphates.

CASIDA JE, BARON RL, ETO M, ENGEL JL.

Biochem Pharmacol. 1963 Jan;12:73-83. No abstract available.

PMID:
14019076
12.

A new and rapid colorimetric determination of acetylcholinesterase activity.

ELLMAN GL, COURTNEY KD, ANDRES V Jr, FEATHER-STONE RM.

Biochem Pharmacol. 1961 Jul;7:88-95. No abstract available.

PMID:
13726518
13.

Sarin (nerve agent GB)-induced differential expression of mRNA coding for the acetylcholinesterase gene in the rat central nervous system.

Damodaran TV, Jones KH, Patel AG, Abou-Donia MB.

Biochem Pharmacol. 2003 Jun 15;65(12):2041-7.

PMID:
12787884
14.
15.

Activation of CPT-11 in mice: identification and analysis of a highly effective plasma esterase.

Morton CL, Wierdl M, Oliver L, Ma MK, Danks MK, Stewart CF, Eiseman JL, Potter PM.

Cancer Res. 2000 Aug 1;60(15):4206-10.

16.
17.

Interaction of organophosphorus compounds with carboxylesterases in the rat.

Jokanović M, Kosanović M, Maksimović M.

Arch Toxicol. 1996;70(7):444-50.

PMID:
8740539
18.
19.

Effect of pretreatment with CBDP on the toxicokinetics of soman stereoisomers in rats and guinea pigs.

Due AH, Trap HC, Van Der Wiel HJ, Benschop HP.

Arch Toxicol. 1993;67(10):706-11.

PMID:
8135661
20.

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