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Items: 1 to 20 of 49

1.

Pausing of RNA polymerase II disrupts DNA-specified nucleosome organization to enable precise gene regulation.

Gilchrist DA, Dos Santos G, Fargo DC, Xie B, Gao Y, Li L, Adelman K.

Cell. 2010 Nov 12;143(4):540-51. doi: 10.1016/j.cell.2010.10.004.

2.

Epigenetic modifications as therapeutic targets.

Kelly TK, De Carvalho DD, Jones PA.

Nat Biotechnol. 2010 Oct;28(10):1069-78. doi: 10.1038/nbt.1678. Review.

3.

A unique H3K4me2 profile marks tissue-specific gene regulation.

Pekowska A, Benoukraf T, Ferrier P, Spicuglia S.

Genome Res. 2010 Nov;20(11):1493-502. doi: 10.1101/gr.109389.110. Epub 2010 Sep 14.

4.

Early mammalian erythropoiesis requires the Dot1L methyltransferase.

Feng Y, Yang Y, Ortega MM, Copeland JN, Zhang M, Jacob JB, Fields TA, Vivian JL, Fields PE.

Blood. 2010 Nov 25;116(22):4483-91. doi: 10.1182/blood-2010-03-276501. Epub 2010 Aug 26.

5.

Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells.

Guenther MG, Frampton GM, Soldner F, Hockemeyer D, Mitalipova M, Jaenisch R, Young RA.

Cell Stem Cell. 2010 Aug 6;7(2):249-57. doi: 10.1016/j.stem.2010.06.015.

6.

TIF1gamma controls erythroid cell fate by regulating transcription elongation.

Bai X, Kim J, Yang Z, Jurynec MJ, Akie TE, Lee J, LeBlanc J, Sessa A, Jiang H, DiBiase A, Zhou Y, Grunwald DJ, Lin S, Cantor AB, Orkin SH, Zon LI.

Cell. 2010 Jul 9;142(1):133-43. doi: 10.1016/j.cell.2010.05.028.

7.

Multiple functions of Ldb1 required for beta-globin activation during erythroid differentiation.

Song SH, Kim A, Ragoczy T, Bender MA, Groudine M, Dean A.

Blood. 2010 Sep 30;116(13):2356-64. doi: 10.1182/blood-2010-03-272252. Epub 2010 Jun 22.

8.

c-Myc regulates transcriptional pause release.

Rahl PB, Lin CY, Seila AC, Flynn RA, McCuine S, Burge CB, Sharp PA, Young RA.

Cell. 2010 Apr 30;141(3):432-45. doi: 10.1016/j.cell.2010.03.030.

9.

Homeodomain-interacting protein kinase 2 plays an important role in normal terminal erythroid differentiation.

Hattangadi SM, Burke KA, Lodish HF.

Blood. 2010 Jun 10;115(23):4853-61. doi: 10.1182/blood-2009-07-235093. Epub 2010 Mar 15.

10.

The genome-wide dynamics of the binding of Ldb1 complexes during erythroid differentiation.

Soler E, Andrieu-Soler C, de Boer E, Bryne JC, Thongjuea S, Stadhouders R, Palstra RJ, Stevens M, Kockx C, van Ijcken W, Hou J, Steinhoff C, Rijkers E, Lenhard B, Grosveld F.

Genes Dev. 2010 Feb 1;24(3):277-89. doi: 10.1101/gad.551810. Erratum in: Genes Dev. 2010 Mar 15;24(6):623.

11.

Insights into GATA-1-mediated gene activation versus repression via genome-wide chromatin occupancy analysis.

Yu M, Riva L, Xie H, Schindler Y, Moran TB, Cheng Y, Yu D, Hardison R, Weiss MJ, Orkin SH, Bernstein BE, Fraenkel E, Cantor AB.

Mol Cell. 2009 Nov 25;36(4):682-95. doi: 10.1016/j.molcel.2009.11.002.

12.

Discovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancy.

Fujiwara T, O'Geen H, Keles S, Blahnik K, Linnemann AK, Kang YA, Choi K, Farnham PJ, Bresnick EH.

Mol Cell. 2009 Nov 25;36(4):667-81. doi: 10.1016/j.molcel.2009.11.001.

13.

Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression.

Cheng Y, Wu W, Kumar SA, Yu D, Deng W, Tripic T, King DC, Chen KB, Zhang Y, Drautz D, Giardine B, Schuster SC, Miller W, Chiaromonte F, Zhang Y, Blobel GA, Weiss MJ, Hardison RC.

Genome Res. 2009 Dec;19(12):2172-84. doi: 10.1101/gr.098921.109. Epub 2009 Nov 3.

14.

Finding distal regulatory elements in the human genome.

Heintzman ND, Ren B.

Curr Opin Genet Dev. 2009 Dec;19(6):541-9. doi: 10.1016/j.gde.2009.09.006. Epub 2009 Oct 23. Review.

15.

Defining the chromatin signature of inducible genes in T cells.

Lim PS, Hardy K, Bunting KL, Ma L, Peng K, Chen X, Shannon MF.

Genome Biol. 2009;10(10):R107. doi: 10.1186/gb-2009-10-10-r107. Epub 2009 Oct 6.

16.

Chromatin poises miRNA- and protein-coding genes for expression.

Barski A, Jothi R, Cuddapah S, Cui K, Roh TY, Schones DE, Zhao K.

Genome Res. 2009 Oct;19(10):1742-51. doi: 10.1101/gr.090951.109. Epub 2009 Aug 27. Erratum in: Genome Res. 2009 Dec;19(12):2343.

17.

Histone hyperacetylation within the beta-globin locus is context-dependent and precedes high-level gene expression.

Fromm G, de Vries C, Byron R, Fields J, Fiering S, Groudine M, Bender MA, Palis J, Bulger M.

Blood. 2009 Oct 15;114(16):3479-88. doi: 10.1182/blood-2009-03-210690. Epub 2009 Aug 18.

18.

Genome-wide analysis of histone methylation reveals chromatin state-based regulation of gene transcription and function of memory CD8+ T cells.

Araki Y, Wang Z, Zang C, Wood WH 3rd, Schones D, Cui K, Roh TY, Lhotsky B, Wersto RP, Peng W, Becker KG, Zhao K, Weng NP.

Immunity. 2009 Jun 19;30(6):912-25. doi: 10.1016/j.immuni.2009.05.006. Epub 2009 Jun 11.

19.

ChIP-Seq of ERalpha and RNA polymerase II defines genes differentially responding to ligands.

Welboren WJ, van Driel MA, Janssen-Megens EM, van Heeringen SJ, Sweep FC, Span PN, Stunnenberg HG.

EMBO J. 2009 May 20;28(10):1418-28. doi: 10.1038/emboj.2009.88. Epub 2009 Apr 4.

20.

Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation.

Cui K, Zang C, Roh TY, Schones DE, Childs RW, Peng W, Zhao K.

Cell Stem Cell. 2009 Jan 9;4(1):80-93. doi: 10.1016/j.stem.2008.11.011.

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