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Items: 1 to 20 of 26

1.

Small molecule agonists of the orphan nuclear receptors steroidogenic factor-1 (SF-1, NR5A1) and liver receptor homologue-1 (LRH-1, NR5A2).

Whitby RJ, Stec J, Blind RD, Dixon S, Leesnitzer LM, Orband-Miller LA, Williams SP, Willson TM, Xu R, Zuercher WJ, Cai F, Ingraham HA.

J Med Chem. 2011 Apr 14;54(7):2266-81. doi: 10.1021/jm1014296. Epub 2011 Mar 10.

2.

Replacement of Rbpj with Rbpjl in the PTF1 complex controls the final maturation of pancreatic acinar cells.

Masui T, Swift GH, Deering T, Shen C, Coats WS, Long Q, Elsässer HP, Magnuson MA, MacDonald RJ.

Gastroenterology. 2010 Jul;139(1):270-80. doi: 10.1053/j.gastro.2010.04.003. Epub 2010 Apr 14.

3.

Cell-specific determinants of peroxisome proliferator-activated receptor gamma function in adipocytes and macrophages.

Lefterova MI, Steger DJ, Zhuo D, Qatanani M, Mullican SE, Tuteja G, Manduchi E, Grant GR, Lazar MA.

Mol Cell Biol. 2010 May;30(9):2078-89. doi: 10.1128/MCB.01651-09. Epub 2010 Feb 22.

4.

The nuclear receptor Nr5a2 can replace Oct4 in the reprogramming of murine somatic cells to pluripotent cells.

Heng JC, Feng B, Han J, Jiang J, Kraus P, Ng JH, Orlov YL, Huss M, Yang L, Lufkin T, Lim B, Ng HH.

Cell Stem Cell. 2010 Feb 5;6(2):167-74. doi: 10.1016/j.stem.2009.12.009. Epub 2010 Jan 21.

5.

Genome-wide profiling of PPARgamma:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis.

Nielsen R, Pedersen TA, Hagenbeek D, Moulos P, Siersbaek R, Megens E, Denissov S, Børgesen M, Francoijs KJ, Mandrup S, Stunnenberg HG.

Genes Dev. 2008 Nov 1;22(21):2953-67. doi: 10.1101/gad.501108.

6.

Liver receptor homolog-1, an emerging metabolic modulator.

Lee YK, Moore DD.

Front Biosci. 2008 May 1;13:5950-8. Review.

PMID:
18508634
7.

Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis.

Lee YK, Schmidt DR, Cummins CL, Choi M, Peng L, Zhang Y, Goodwin B, Hammer RE, Mangelsdorf DJ, Kliewer SA.

Mol Endocrinol. 2008 Jun;22(6):1345-56. doi: 10.1210/me.2007-0565. Epub 2008 Mar 6.

8.

Overview of image analysis, image importing, and image processing using freeware.

Bearer EL.

Curr Protoc Mol Biol. 2003 Aug;Chapter 14:Unit 14.15. doi: 10.1002/0471142727.mb1415s63.

9.

Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex.

Masui T, Long Q, Beres TM, Magnuson MA, MacDonald RJ.

Genes Dev. 2007 Oct 15;21(20):2629-43.

10.

DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists.

Huang DW, Sherman BT, Tan Q, Kir J, Liu D, Bryant D, Guo Y, Stephens R, Baseler MW, Lane HC, Lempicki RA.

Nucleic Acids Res. 2007 Jul;35(Web Server issue):W169-75. Epub 2007 Jun 18.

11.

Genome-wide analysis of estrogen receptor binding sites.

Carroll JS, Meyer CA, Song J, Li W, Geistlinger TR, Eeckhoute J, Brodsky AS, Keeton EK, Fertuck KC, Hall GF, Wang Q, Bekiranov S, Sementchenko V, Fox EA, Silver PA, Gingeras TR, Liu XS, Brown M.

Nat Genet. 2006 Nov;38(11):1289-97. Epub 2006 Oct 1.

PMID:
17013392
12.
13.

Orphan nuclear receptor LRH-1 is required to maintain Oct4 expression at the epiblast stage of embryonic development.

Gu P, Goodwin B, Chung AC, Xu X, Wheeler DA, Price RR, Galardi C, Peng L, Latour AM, Koller BH, Gossen J, Kliewer SA, Cooney AJ.

Mol Cell Biol. 2005 May;25(9):3492-505.

14.

LRH-1: an orphan nuclear receptor involved in development, metabolism and steroidogenesis.

Fayard E, Auwerx J, Schoonjans K.

Trends Cell Biol. 2004 May;14(5):250-60. Review.

PMID:
15130581
15.

The fetoprotein transcription factor (FTF) gene is essential to embryogenesis and cholesterol homeostasis and is regulated by a DR4 element.

Paré JF, Malenfant D, Courtemanche C, Jacob-Wagner M, Roy S, Allard D, Bélanger L.

J Biol Chem. 2004 May 14;279(20):21206-16. Epub 2004 Mar 10.

16.

Liver receptor homolog 1 controls the expression of carboxyl ester lipase.

Fayard E, Schoonjans K, Annicotte JS, Auwerx J.

J Biol Chem. 2003 Sep 12;278(37):35725-31. Epub 2003 Jul 9.

17.

The role of PTF1-P48 in pancreatic acinar gene expression.

Rose SD, Swift GH, Peyton MJ, Hammer RE, MacDonald RJ.

J Biol Chem. 2001 Nov 23;276(47):44018-26. Epub 2001 Sep 18.

20.

Identification of a nuclear receptor for bile acids.

Makishima M, Okamoto AY, Repa JJ, Tu H, Learned RM, Luk A, Hull MV, Lustig KD, Mangelsdorf DJ, Shan B.

Science. 1999 May 21;284(5418):1362-5.

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