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Items: 1 to 20 of 42

1.

miR-17~92 cooperates with RB pathway mutations to promote retinoblastoma.

Conkrite K, Sundby M, Mukai S, Thomson JM, Mu D, Hammond SM, MacPherson D.

Genes Dev. 2011 Aug 15;25(16):1734-45. doi: 10.1101/gad.17027411. Epub 2011 Aug 4.

2.

RB1, development, and cancer.

Chinnam M, Goodrich DW.

Curr Top Dev Biol. 2011;94:129-69. doi: 10.1016/B978-0-12-380916-2.00005-X. Review.

3.

The miR-17-92 microRNA cluster regulates multiple components of the TGF-β pathway in neuroblastoma.

Mestdagh P, Boström AK, Impens F, Fredlund E, Van Peer G, De Antonellis P, von Stedingk K, Ghesquière B, Schulte S, Dews M, Thomas-Tikhonenko A, Schulte JH, Zollo M, Schramm A, Gevaert K, Axelson H, Speleman F, Vandesompele J.

Mol Cell. 2010 Dec 10;40(5):762-73. doi: 10.1016/j.molcel.2010.11.038.

4.

G1 arrest and differentiation can occur independently of Rb family function.

Wirt SE, Adler AS, Gebala V, Weimann JM, Schaffer BE, Saddic LA, Viatour P, Vogel H, Chang HY, Meissner A, Sage J.

J Cell Biol. 2010 Nov 15;191(4):809-25. doi: 10.1083/jcb.201003048. Epub 2010 Nov 8.

5.

Rb deletion in mouse mammary progenitors induces luminal-B or basal-like/EMT tumor subtypes depending on p53 status.

Jiang Z, Deng T, Jones R, Li H, Herschkowitz JI, Liu JC, Weigman VJ, Tsao MS, Lane TF, Perou CM, Zacksenhaus E.

J Clin Invest. 2010 Sep;120(9):3296-309. doi: 10.1172/JCI41490. Epub 2010 Aug 2.

6.

Tandem E2F binding sites in the promoter of the p107 cell cycle regulator control p107 expression and its cellular functions.

Burkhart DL, Wirt SE, Zmoos AF, Kareta MS, Sage J.

PLoS Genet. 2010 Jun 24;6(6):e1001003. doi: 10.1371/journal.pgen.1001003.

7.

Loss of p130 accelerates tumor development in a mouse model for human small-cell lung carcinoma.

Schaffer BE, Park KS, Yiu G, Conklin JF, Lin C, Burkhart DL, Karnezis AN, Sweet-Cordero EA, Sage J.

Cancer Res. 2010 May 15;70(10):3877-83. doi: 10.1158/0008-5472.CAN-09-4228. Epub 2010 Apr 20.

8.

mir-17-92, a cluster of miRNAs in the midst of the cancer network.

Olive V, Jiang I, He L.

Int J Biochem Cell Biol. 2010 Aug;42(8):1348-54. doi: 10.1016/j.biocel.2010.03.004. Epub 2010 Mar 19. Review.

9.

Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia.

Mavrakis KJ, Wolfe AL, Oricchio E, Palomero T, de Keersmaecker K, McJunkin K, Zuber J, James T, Khan AA, Leslie CS, Parker JS, Paddison PJ, Tam W, Ferrando A, Wendel HG.

Nat Cell Biol. 2010 Apr;12(4):372-9. doi: 10.1038/ncb2037. Epub 2010 Feb 28.

10.

Division and apoptosis of E2f-deficient retinal progenitors.

Chen D, Pacal M, Wenzel P, Knoepfler PS, Leone G, Bremner R.

Nature. 2009 Dec 17;462(7275):925-9. doi: 10.1038/nature08544.

11.

miR-19 is a key oncogenic component of mir-17-92.

Olive V, Bennett MJ, Walker JC, Ma C, Jiang I, Cordon-Cardo C, Li QJ, Lowe SW, Hannon GJ, He L.

Genes Dev. 2009 Dec 15;23(24):2839-49. doi: 10.1101/gad.1861409.

12.

Genetic dissection of the miR-17~92 cluster of microRNAs in Myc-induced B-cell lymphomas.

Mu P, Han YC, Betel D, Yao E, Squatrito M, Ogrodowski P, de Stanchina E, D'Andrea A, Sander C, Ventura A.

Genes Dev. 2009 Dec 15;23(24):2806-11. doi: 10.1101/gad.1872909.

13.

Mutation of p107 exacerbates the consequences of Rb loss in embryonic tissues and causes cardiac and blood vessel defects.

Berman SD, West JC, Danielian PS, Caron AM, Stone JR, Lees JA.

Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):14932-6. doi: 10.1073/pnas.0902408106. Epub 2009 Aug 19.

14.

MicroRNAs and cancer: short RNAs go a long way.

Ventura A, Jacks T.

Cell. 2009 Feb 20;136(4):586-91. doi: 10.1016/j.cell.2009.02.005.

15.

The miR-17~92 cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma.

Uziel T, Karginov FV, Xie S, Parker JS, Wang YD, Gajjar A, He L, Ellison D, Gilbertson RJ, Hannon G, Roussel MF.

Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2812-7. doi: 10.1073/pnas.0809579106. Epub 2009 Feb 5.

16.

MicroRNAs: target recognition and regulatory functions.

Bartel DP.

Cell. 2009 Jan 23;136(2):215-33. doi: 10.1016/j.cell.2009.01.002. Review.

17.

The common mechanisms of transformation by the small DNA tumor viruses: The inactivation of tumor suppressor gene products: p53.

Levine AJ.

Virology. 2009 Feb 20;384(2):285-93. doi: 10.1016/j.virol.2008.09.034. Epub 2008 Dec 11. Review.

18.

Antagomir-17-5p abolishes the growth of therapy-resistant neuroblastoma through p21 and BIM.

Fontana L, Fiori ME, Albini S, Cifaldi L, Giovinazzi S, Forloni M, Boldrini R, Donfrancesco A, Federici V, Giacomini P, Peschle C, Fruci D.

PLoS One. 2008 May 21;3(5):e2236. doi: 10.1371/journal.pone.0002236.

19.

Insights from mouse models into human retinoblastoma.

Macpherson D.

Cell Div. 2008 May 19;3:9. doi: 10.1186/1747-1028-3-9.

20.

MicroRNA 29c is down-regulated in nasopharyngeal carcinomas, up-regulating mRNAs encoding extracellular matrix proteins.

Sengupta S, den Boon JA, Chen IH, Newton MA, Stanhope SA, Cheng YJ, Chen CJ, Hildesheim A, Sugden B, Ahlquist P.

Proc Natl Acad Sci U S A. 2008 Apr 15;105(15):5874-8. doi: 10.1073/pnas.0801130105. Epub 2008 Apr 4.

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