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Items: 1 to 20 of 28


HLA-DPB1 and DPB2 are genetic loci for systemic sclerosis: a genome-wide association study in Koreans with replication in North Americans.

Zhou X, Lee JE, Arnett FC, Xiong M, Park MY, Yoo YK, Shin ES, Reveille JD, Mayes MD, Kim JH, Song R, Choi JY, Park JA, Lee YJ, Lee EY, Song YW, Lee EB.

Arthritis Rheum. 2009 Dec;60(12):3807-14. doi: 10.1002/art.24982.


Major histocompatibility complex (MHC) class II alleles, haplotypes and epitopes which confer susceptibility or protection in systemic sclerosis: analyses in 1300 Caucasian, African-American and Hispanic cases and 1000 controls.

Arnett FC, Gourh P, Shete S, Ahn CW, Honey RE, Agarwal SK, Tan FK, McNearney T, Fischbach M, Fritzler MJ, Mayes MD, Reveille JD.

Ann Rheum Dis. 2010 May;69(5):822-7. doi: 10.1136/ard.2009.111906. Epub 2009 Jul 12. Erratum in: Ann Rheum Dis. 2011 May;70(5):880.


The many faces of scleroderma.

Steen VD.

Rheum Dis Clin North Am. 2008 Feb;34(1):1-15; v. doi: 10.1016/j.rdc.2007.12.001. Review.


Nonclassic functions of human topoisomerase I: genome-wide and pharmacologic analyses.

Miao ZH, Player A, Shankavaram U, Wang YH, Zimonjic DB, Lorenzi PL, Liao ZY, Liu H, Shimura T, Zhang HL, Meng LH, Zhang YW, Kawasaki ES, Popescu NC, Aladjem MI, Goldstein DJ, Weinstein JN, Pommier Y.

Cancer Res. 2007 Sep 15;67(18):8752-61.


Modification of nuclear PML protein by SUMO-1 regulates Fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts.

Meinecke I, Cinski A, Baier A, Peters MA, Dankbar B, Wille A, Drynda A, Mendoza H, Gay RE, Hay RT, Ink B, Gay S, Pap T.

Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5073-8. Epub 2007 Mar 14.


Human DNA topoisomerase I: relaxation, roles, and damage control.

Leppard JB, Champoux JJ.

Chromosoma. 2005 Jul;114(2):75-85. Epub 2005 Apr 14. Review.


SUMO wrestling with type 1 diabetes.

Li M, Guo D, Isales CM, Eizirik DL, Atkinson M, She JX, Wang CY.

J Mol Med (Berl). 2005 Jul;83(7):504-13. Epub 2005 Apr 2. Review.


Direct binding of anti-DNA topoisomerase I autoantibodies to the cell surface of fibroblasts in patients with systemic sclerosis.

Hénault J, Tremblay M, Clément I, Raymond Y, Senécal JL.

Arthritis Rheum. 2004 Oct;50(10):3265-74.


Distinct effects of topoisomerase I and RNA polymerase I inhibitors suggest a dual mechanism of nucleolar/nucleoplasmic partitioning of topoisomerase I.

Christensen MO, Krokowski RM, Barthelmes HU, Hock R, Boege F, Mielke C.

J Biol Chem. 2004 May 21;279(21):21873-82. Epub 2004 Mar 9.


New insights into the pathogenesis of systemic sclerosis.

Tamby MC, Chanseaud Y, Guillevin L, Mouthon L.

Autoimmun Rev. 2003 May;2(3):152-7. Review.


Sumoylation of topoisomerase I is involved in its partitioning between nucleoli and nucleoplasm and its clearing from nucleoli in response to camptothecin.

Rallabhandi P, Hashimoto K, Mo YY, Beck WT, Moitra PK, D'Arpa P.

J Biol Chem. 2002 Oct 18;277(42):40020-6. Epub 2002 Jul 30.


Cellular roles of DNA topoisomerases: a molecular perspective.

Wang JC.

Nat Rev Mol Cell Biol. 2002 Jun;3(6):430-40. Review.


Topotecan and the development of scleroderma or a scleroderma-like illness.

Ene-Stroescu D, Ellman MH, Peterson CE.

Arthritis Rheum. 2002 Mar;46(3):844-5. No abstract available.


Subnuclear distribution of topoisomerase I is linked to ongoing transcription and p53 status.

Mao Y, Mehl IR, Muller MT.

Proc Natl Acad Sci U S A. 2002 Feb 5;99(3):1235-40. Epub 2002 Jan 22. Erratum in: Proc Natl Acad Sci U S A 2002 Mar 19;99(6):4134.


Nucleolar delocalization of human topoisomerase I in response to topotecan correlates with sumoylation of the protein.

Mo YY, Yu Y, Shen Z, Beck WT.

J Biol Chem. 2002 Jan 25;277(4):2958-64. Epub 2001 Nov 14.


Longitudinal analysis of autoantibody response to topoisomerase I in systemic sclerosis.

Kuwana M, Kaburaki J, Mimori T, Kawakami Y, Tojo T.

Arthritis Rheum. 2000 May;43(5):1074-84.


Is anti-topoisomerase I a serum marker of pulmonary involvement in systemic sclerosis?

Diot E, Giraudeau B, Diot P, Degenne D, Ritz L, Guilmot JL, Lemarié E.

Chest. 1999 Sep;116(3):715-20.


Systemic sclerosis: an autoantibody mosaic.

Bunn CC, Black CM.

Clin Exp Immunol. 1999 Aug;117(2):207-8. Review. No abstract available.


Autoantigen components recognizable by scleroderma sera are exported via ectocytosis of fibroblasts.

Hsu TC, Lee TL, Tsay GJ.

Br J Rheumatol. 1997 Oct;36(10):1038-44.


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