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Items: 1 to 20 of 22

1.

Characterization of the terminal activation step catalyzed by oxygenase CmmOIV of the chromomycin biosynthetic pathway from Streptomyces griseus.

Bosserman MA, Flórez AB, Shaaban KA, Braña AF, Salas JA, Méndez C, Rohr J.

Biochemistry. 2011 Mar 1;50(8):1421-8. doi: 10.1021/bi1016205.

2.

DNA binding characteristics of mithramycin and chromomycin analogues obtained by combinatorial biosynthesis.

Barceló F, Ortiz-Lombardía M, Martorell M, Oliver M, Méndez C, Salas JA, Portugal J.

Biochemistry. 2010 Dec 14;49(49):10543-52. doi: 10.1021/bi101398s.

PMID:
21067184
3.

Generation of new derivatives of the antitumor antibiotic mithramycin by altering the glycosylation pattern through combinatorial biosynthesis.

Pérez M, Baig I, Braña AF, Salas JA, Rohr J, Méndez C.

Chembiochem. 2008 Sep 22;9(14):2295-304. doi: 10.1002/cbic.200800299.

4.

The aureolic acid family of antitumor compounds: structure, mode of action, biosynthesis, and novel derivatives.

Lombó F, Menéndez N, Salas JA, Méndez C.

Appl Microbiol Biotechnol. 2006 Nov;73(1):1-14. Review.

PMID:
17013601
5.

Novel GC-rich DNA-binding compound produced by a genetically engineered mutant of the mithramycin producer Streptomyces argillaceus exhibits improved transcriptional repressor activity: implications for cancer therapy.

Albertini V, Jain A, Vignati S, Napoli S, Rinaldi A, Kwee I, Nur-e-Alam M, Bergant J, Bertoni F, Carbone GM, Rohr J, Catapano CV.

Nucleic Acids Res. 2006 Mar 29;34(6):1721-34.

7.

Biosynthesis of the antitumor chromomycin A3 in Streptomyces griseus: analysis of the gene cluster and rational design of novel chromomycin analogs.

Menéndez N, Nur-e-Alam M, Braña AF, Rohr J, Salas JA, Méndez C.

Chem Biol. 2004 Jan;11(1):21-32.

PMID:
15112992
8.

Selective incells by chromomycin A3.

WAKISAKA G, UCHINO H, NAKAMURA T, SOTOVAYASHI H, SHIRAKAWA S, ADACHI A, SAKURAI M.

Nature. 1963 Apr 27;198:385-6. No abstract available.

PMID:
13998381
9.

Studies on the antitumor activity of chromomycin A3.

SATO K, OKAMURA N, UTAGAWA K, ITO Y, WATANABE M.

Sci Rep Res Inst Tohoku Univ Med. 1960 Feb;9:224-32. No abstract available.

PMID:
13854641
10.

Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.

Remsing LL, González AM, Nur-e-Alam M, Fernández-Lozano MJ, Braña AF, Rix U, Oliveira MA, Méndez C, Salas JA, Rohr J.

J Am Chem Soc. 2003 May 14;125(19):5745-53.

11.
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13.

Solution structure of the novel antitumor drug UCH9 complexed with d(TTGGCCAA)2 as determined by NMR.

Katahira R, Katahira M, Yamashita Y, Ogawa H, Kyogoku Y, Yoshida M.

Nucleic Acids Res. 1998 Feb 1;26(3):744-55.

14.

Solution structure of the mithramycin dimer-DNA complex.

Sastry M, Patel DJ.

Biochemistry. 1993 Jul 6;32(26):6588-604.

PMID:
8329387
15.

Solution structure of mithramycin dimers bound to partially overlapping sites on DNA.

Sastry M, Fiala R, Patel DJ.

J Mol Biol. 1995 Sep 1;251(5):674-89.

PMID:
7666419
16.

DNA modification and cancer.

Waring MJ.

Annu Rev Biochem. 1981;50:159-92. Review. No abstract available.

PMID:
6168236
17.

Chromomycin A-2, A-3 and A-4.

Miyamoto M, Kawamatsu Y, Kawashima K, Shinohara M, Tanaka K, Tatsuoka S, Nakanishi K.

Tetrahedron. 1967 Jan;23(1):421-37. No abstract available.

PMID:
6037288
18.

The full structures of three chromomycins, A2, A3, and A4.

Miyamoto M, Kawamatsu Y, Kawashima K, Shinohara M, Nakanishi K.

Tetrahedron Lett. 1966 Feb;6:545-52. No abstract available.

PMID:
5905316
19.

Aureolic acid group of anti-tumour antibiotics.

Berlin YU, Kiseleva OA, Kolosov MN, Shemyakin MM, Soifer VS.

Nature. 1968 Apr 13;218(5137):193-4. No abstract available.

PMID:
4967057
20.

Effects of mithramycin on bone resorption in vitro.

Cortes EP, Holland JF, Moskowitz R, Depoli E.

Cancer Res. 1972 Jan;32(1):74-6. No abstract available.

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