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Items: 1 to 20 of 39

1.

Phosphate and R2D2 restrict the substrate specificity of Dicer-2, an ATP-driven ribonuclease.

Cenik ES, Fukunaga R, Lu G, Dutcher R, Wang Y, Tanaka Hall TM, Zamore PD.

Mol Cell. 2011 Apr 22;42(2):172-84. doi: 10.1016/j.molcel.2011.03.002.

2.

Dicer's helicase domain discriminates dsRNA termini to promote an altered reaction mode.

Welker NC, Maity TS, Ye X, Aruscavage PJ, Krauchuk AA, Liu Q, Bass BL.

Mol Cell. 2011 Mar 4;41(5):589-99. doi: 10.1016/j.molcel.2011.02.005.

3.

Structural basis for 5'-nucleotide base-specific recognition of guide RNA by human AGO2.

Frank F, Sonenberg N, Nagar B.

Nature. 2010 Jun 10;465(7299):818-22. doi: 10.1038/nature09039.

PMID:
20505670
4.

Dicer-independent primal RNAs trigger RNAi and heterochromatin formation.

Halic M, Moazed D.

Cell. 2010 Feb 19;140(4):504-16. doi: 10.1016/j.cell.2010.01.019.

5.

Structural insights into RNA processing by the human RISC-loading complex.

Wang HW, Noland C, Siridechadilok B, Taylor DW, Ma E, Felderer K, Doudna JA, Nogales E.

Nat Struct Mol Biol. 2009 Nov;16(11):1148-53. doi: 10.1038/nsmb.1673.

6.

Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes.

Wang Y, Juranek S, Li H, Sheng G, Wardle GS, Tuschl T, Patel DJ.

Nature. 2009 Oct 8;461(7265):754-61. doi: 10.1038/nature08434.

7.

RNAi in budding yeast.

Drinnenberg IA, Weinberg DE, Xie KT, Mower JP, Wolfe KH, Fink GR, Bartel DP.

Science. 2009 Oct 23;326(5952):544-50. doi: 10.1126/science.1176945.

8.

E. coli RNase III(E38A) generates discrete-sized products from long dsRNA.

Xiao J, Feehery CE, Tzertzinis G, Maina CV.

RNA. 2009 May;15(5):984-91. doi: 10.1261/rna.1196509.

9.

Small RNAs as guardians of the genome.

Malone CD, Hannon GJ.

Cell. 2009 Feb 20;136(4):656-68. doi: 10.1016/j.cell.2009.01.045. Review.

10.

An endogenous small interfering RNA pathway in Drosophila.

Czech B, Malone CD, Zhou R, Stark A, Schlingeheyde C, Dus M, Perrimon N, Kellis M, Wohlschlegel JA, Sachidanandam R, Hannon GJ, Brennecke J.

Nature. 2008 Jun 5;453(7196):798-802. doi: 10.1038/nature07007.

11.

The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs.

Okamura K, Chung WJ, Ruby JG, Guo H, Bartel DP, Lai EC.

Nature. 2008 Jun 5;453(7196):803-6. doi: 10.1038/nature07015.

12.

Structural and biochemical insights into the dicing mechanism of mouse Dicer: a conserved lysine is critical for dsRNA cleavage.

Du Z, Lee JK, Tjhen R, Stroud RM, James TL.

Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2391-6. doi: 10.1073/pnas.0711506105.

13.

A stepwise model for double-stranded RNA processing by ribonuclease III.

Gan J, Shaw G, Tropea JE, Waugh DS, Court DL, Ji X.

Mol Microbiol. 2008 Jan;67(1):143-54.

15.

Homodimeric structure and double-stranded RNA cleavage activity of the C-terminal RNase III domain of human dicer.

Takeshita D, Zenno S, Lee WC, Nagata K, Saigo K, Tanokura M.

J Mol Biol. 2007 Nov 16;374(1):106-20.

PMID:
17920623
16.

Structural determinants of RNA recognition and cleavage by Dicer.

MacRae IJ, Zhou K, Doudna JA.

Nat Struct Mol Biol. 2007 Oct;14(10):934-40.

PMID:
17873886
17.

Ribonuclease revisited: structural insights into ribonuclease III family enzymes.

MacRae IJ, Doudna JA.

Curr Opin Struct Biol. 2007 Feb;17(1):138-45. Review.

PMID:
17194582
18.

Structural insight into the mechanism of double-stranded RNA processing by ribonuclease III.

Gan J, Tropea JE, Austin BP, Court DL, Waugh DS, Ji X.

Cell. 2006 Jan 27;124(2):355-66.

19.

Structural basis for double-stranded RNA processing by Dicer.

Macrae IJ, Zhou K, Li F, Repic A, Brooks AN, Cande WZ, Adams PD, Doudna JA.

Science. 2006 Jan 13;311(5758):195-8.

20.
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