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Items: 1 to 20 of 73

1.

Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited.

Deelen J, Beekman M, Uh HW, Helmer Q, Kuningas M, Christiansen L, Kremer D, van der Breggen R, Suchiman HE, Lakenberg N, van den Akker EB, Passtoors WM, Tiemeier H, van Heemst D, de Craen AJ, Rivadeneira F, de Geus EJ, Perola M, van der Ouderaa FJ, Gunn DA, Boomsma DI, Uitterlinden AG, Christensen K, van Duijn CM, Heijmans BT, Houwing-Duistermaat JJ, Westendorp RG, Slagboom PE.

Aging Cell. 2011 Aug;10(4):686-98. doi: 10.1111/j.1474-9726.2011.00705.x. Epub 2011 May 6.

2.

Biodemography of human ageing.

Vaupel JW.

Nature. 2010 Mar 25;464(7288):536-42. doi: 10.1038/nature08984. Review.

3.

Neural mechanisms of ageing and cognitive decline.

Bishop NA, Lu T, Yankner BA.

Nature. 2010 Mar 25;464(7288):529-35. doi: 10.1038/nature08983. Review.

4.

The genetics of ageing.

Kenyon CJ.

Nature. 2010 Mar 25;464(7288):504-12. doi: 10.1038/nature08980. Review. Erratum in: Nature. 2010 Sep 30;467(7315):622.

PMID:
20336132
5.

A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium.

Newman AB, Walter S, Lunetta KL, Garcia ME, Slagboom PE, Christensen K, Arnold AM, Aspelund T, Aulchenko YS, Benjamin EJ, Christiansen L, D'Agostino RB Sr, Fitzpatrick AL, Franceschini N, Glazer NL, Gudnason V, Hofman A, Kaplan R, Karasik D, Kelly-Hayes M, Kiel DP, Launer LJ, Marciante KD, Massaro JM, Miljkovic I, Nalls MA, Hernandez D, Psaty BM, Rivadeneira F, Rotter J, Seshadri S, Smith AV, Taylor KD, Tiemeier H, Uh HW, Uitterlinden AG, Vaupel JW, Walston J, Westendorp RG, Harris TB, Lumley T, van Duijn CM, Murabito JM.

J Gerontol A Biol Sci Med Sci. 2010 May;65(5):478-87. doi: 10.1093/gerona/glq028. Epub 2010 Mar 18.

6.

Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of prospective meta-analyses of genome-wide association studies from 5 cohorts.

Psaty BM, O'Donnell CJ, Gudnason V, Lunetta KL, Folsom AR, Rotter JI, Uitterlinden AG, Harris TB, Witteman JC, Boerwinkle E; CHARGE Consortium.

Circ Cardiovasc Genet. 2009 Feb;2(1):73-80. doi: 10.1161/CIRCGENETICS.108.829747.

7.

Emerging roles of Wnts in the adult nervous system.

Inestrosa NC, Arenas E.

Nat Rev Neurosci. 2010 Feb;11(2):77-86. doi: 10.1038/nrn2755. Epub 2009 Dec 16. Review.

PMID:
20010950
8.

Next-generation sequencing in aging research: emerging applications, problems, pitfalls and possible solutions.

de Magalhães JP, Finch CE, Janssens G.

Ageing Res Rev. 2010 Jul;9(3):315-23. doi: 10.1016/j.arr.2009.10.006. Epub 2009 Nov 10. Review.

9.

Genetic association of FOXO1A and FOXO3A with longevity trait in Han Chinese populations.

Li Y, Wang WJ, Cao H, Lu J, Wu C, Hu FY, Guo J, Zhao L, Yang F, Zhang YX, Li W, Zheng GY, Cui H, Chen X, Zhu Z, He H, Dong B, Mo X, Zeng Y, Tian XL.

Hum Mol Genet. 2009 Dec 15;18(24):4897-904. doi: 10.1093/hmg/ddp459. Epub 2009 Sep 29.

10.

Genotype imputation.

Li Y, Willer C, Sanna S, Abecasis G.

Annu Rev Genomics Hum Genet. 2009;10:387-406. doi: 10.1146/annurev.genom.9.081307.164242. Review.

11.

Wnt won the war: antagonistic role of Wnt over Shh controls dorso-ventral patterning of the vertebrate neural tube.

Ulloa F, Martí E.

Dev Dyn. 2010 Jan;239(1):69-76. doi: 10.1002/dvdy.22058. Review.

12.

Tumor suppressor function of BCSC-1 in nasopharyngeal carcinoma.

Zhou YQ, Chen SL, Ju JY, Shen L, Liu Y, Zhen S, Lv N, He ZG, Zhu LP.

Cancer Sci. 2009 Oct;100(10):1817-22. doi: 10.1111/j.1349-7006.2009.01261.x. Epub 2009 Jun 24.

13.

Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity.

Pawlikowska L, Hu D, Huntsman S, Sung A, Chu C, Chen J, Joyner AH, Schork NJ, Hsueh WC, Reiner AP, Psaty BM, Atzmon G, Barzilai N, Cummings SR, Browner WS, Kwok PY, Ziv E; Study of Osteoporotic Fractures.

Aging Cell. 2009 Aug;8(4):460-72. doi: 10.1111/j.1474-9726.2009.00493.x. Epub 2009 May 31.

14.

Physiological functions of the HECT family of ubiquitin ligases.

Rotin D, Kumar S.

Nat Rev Mol Cell Biol. 2009 Jun;10(6):398-409. doi: 10.1038/nrm2690. Epub 2009 May 13. Review.

PMID:
19436320
15.

Genome-wide association study identifies eight loci associated with blood pressure.

Newton-Cheh C, Johnson T, Gateva V, Tobin MD, Bochud M, Coin L, Najjar SS, Zhao JH, Heath SC, Eyheramendy S, Papadakis K, Voight BF, Scott LJ, Zhang F, Farrall M, Tanaka T, Wallace C, Chambers JC, Khaw KT, Nilsson P, van der Harst P, Polidoro S, Grobbee DE, Onland-Moret NC, Bots ML, Wain LV, Elliott KS, Teumer A, Luan J, Lucas G, Kuusisto J, Burton PR, Hadley D, McArdle WL; Wellcome Trust Case Control Consortium, Brown M, Dominiczak A, Newhouse SJ, Samani NJ, Webster J, Zeggini E, Beckmann JS, Bergmann S, Lim N, Song K, Vollenweider P, Waeber G, Waterworth DM, Yuan X, Groop L, Orho-Melander M, Allione A, Di Gregorio A, Guarrera S, Panico S, Ricceri F, Romanazzi V, Sacerdote C, Vineis P, Barroso I, Sandhu MS, Luben RN, Crawford GJ, Jousilahti P, Perola M, Boehnke M, Bonnycastle LL, Collins FS, Jackson AU, Mohlke KL, Stringham HM, Valle TT, Willer CJ, Bergman RN, Morken MA, Döring A, Gieger C, Illig T, Meitinger T, Org E, Pfeufer A, Wichmann HE, Kathiresan S, Marrugat J, O'Donnell CJ, Schwartz SM, Siscovick DS, Subirana I, Freimer NB, Hartikainen AL, McCarthy MI, O'Reilly PF, Peltonen L, Pouta A, de Jong PE, Snieder H, van Gilst WH, Clarke R, Goel A, Hamsten A, Peden JF, Seedorf U, Syvänen AC, Tognoni G, Lakatta EG, Sanna S, Scheet P, Schlessinger D, Scuteri A, Dörr M, Ernst F, Felix SB, Homuth G, Lorbeer R, Reffelmann T, Rettig R, Völker U, Galan P, Gut IG, Hercberg S, Lathrop GM, Zelenika D, Deloukas P, Soranzo N, Williams FM, Zhai G, Salomaa V, Laakso M, Elosua R, Forouhi NG, Völzke H, Uiterwaal CS, van der Schouw YT, Numans ME, Matullo G, Navis G, Berglund G, Bingham SA, Kooner JS, Connell JM, Bandinelli S, Ferrucci L, Watkins H, Spector TD, Tuomilehto J, Altshuler D, Strachan DP, Laan M, Meneton P, Wareham NJ, Uda M, Jarvelin MR, Mooser V, Melander O, Loos RJ, Elliott P, Abecasis GR, Caulfield M, Munroe PB.

Nat Genet. 2009 Jun;41(6):666-76. doi: 10.1038/ng.361. Epub 2009 May 10.

16.

Genome-wide association study of blood pressure and hypertension.

Levy D, Ehret GB, Rice K, Verwoert GC, Launer LJ, Dehghan A, Glazer NL, Morrison AC, Johnson AD, Aspelund T, Aulchenko Y, Lumley T, Köttgen A, Vasan RS, Rivadeneira F, Eiriksdottir G, Guo X, Arking DE, Mitchell GF, Mattace-Raso FU, Smith AV, Taylor K, Scharpf RB, Hwang SJ, Sijbrands EJ, Bis J, Harris TB, Ganesh SK, O'Donnell CJ, Hofman A, Rotter JI, Coresh J, Benjamin EJ, Uitterlinden AG, Heiss G, Fox CS, Witteman JC, Boerwinkle E, Wang TJ, Gudnason V, Larson MG, Chakravarti A, Psaty BM, van Duijn CM.

Nat Genet. 2009 Jun;41(6):677-87. doi: 10.1038/ng.384. Epub 2009 May 10.

17.

Association of the FOXO3A locus with extreme longevity in a southern Italian centenarian study.

Anselmi CV, Malovini A, Roncarati R, Novelli V, Villa F, Condorelli G, Bellazzi R, Puca AA.

Rejuvenation Res. 2009 Apr;12(2):95-104. doi: 10.1089/rej.2008.0827.

PMID:
19415983
18.

LMO4 controls the balance between excitatory and inhibitory spinal V2 interneurons.

Joshi K, Lee S, Lee B, Lee JW, Lee SK.

Neuron. 2009 Mar 26;61(6):839-51. doi: 10.1016/j.neuron.2009.02.011.

19.

Association of FOXO3A variation with human longevity confirmed in German centenarians.

Flachsbart F, Caliebe A, Kleindorp R, Blanché H, von Eller-Eberstein H, Nikolaus S, Schreiber S, Nebel A.

Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2700-5. doi: 10.1073/pnas.0809594106. Epub 2009 Feb 5.

20.

The Human Ageing Genomic Resources: online databases and tools for biogerontologists.

de Magalhães JP, Budovsky A, Lehmann G, Costa J, Li Y, Fraifeld V, Church GM.

Aging Cell. 2009 Feb;8(1):65-72. doi: 10.1111/j.1474-9726.2008.00442.x. Epub 2008 Nov 5. Review.

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