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Items: 1 to 20 of 42

1.

Experimental and computational analysis of polyglutamine-mediated cytotoxicity.

Tang MY, Proctor CJ, Woulfe J, Gray DA.

PLoS Comput Biol. 2010 Sep 23;6(9). pii: e1000944. doi: 10.1371/journal.pcbi.1000944.

2.

Heat shock protein 90 in neurodegenerative diseases.

Luo W, Sun W, Taldone T, Rodina A, Chiosis G.

Mol Neurodegener. 2010 Jun 3;5:24. doi: 10.1186/1750-1326-5-24.

3.

Oxidative modification of nuclear mitogen-activated protein kinase phosphatase 1 is involved in transforming growth factor beta1-induced expression of plasminogen activator inhibitor 1 in fibroblasts.

Liu RM, Choi J, Wu JH, Gaston Pravia KA, Lewis KM, Brand JD, Mochel NS, Krzywanski DM, Lambeth JD, Hagood JS, Forman HJ, Thannickal VJ, Postlethwait EM.

J Biol Chem. 2010 May 21;285(21):16239-47. doi: 10.1074/jbc.M110.111732. Epub 2010 Mar 12.

4.

GSK3 and p53 - is there a link in Alzheimer's disease?

Proctor CJ, Gray DA.

Mol Neurodegener. 2010 Jan 26;5:7. doi: 10.1186/1750-1326-5-7.

5.

Feedback between p21 and reactive oxygen production is necessary for cell senescence.

Passos JF, Nelson G, Wang C, Richter T, Simillion C, Proctor CJ, Miwa S, Olijslagers S, Hallinan J, Wipat A, Saretzki G, Rudolph KL, Kirkwood TB, von Zglinicki T.

Mol Syst Biol. 2010;6:347. doi: 10.1038/msb.2010.5. Epub 2010 Feb 16.

6.

Protein aggregation as a paradigm of aging.

Lindner AB, Demarez A.

Biochim Biophys Acta. 2009 Oct;1790(10):980-96. doi: 10.1016/j.bbagen.2009.06.005. Epub 2009 Jun 13. Review.

PMID:
19527771
7.

The role of glycogen synthase kinase 3 in the early stages of Alzheimers' disease.

Hernández F, Avila J.

FEBS Lett. 2008 Nov 26;582(28):3848-54. doi: 10.1016/j.febslet.2008.10.026. Epub 2008 Oct 26. Review.

8.

Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging.

Morimoto RI.

Genes Dev. 2008 Jun 1;22(11):1427-38. doi: 10.1101/gad.1657108. Review.

9.

Akt and CHIP coregulate tau degradation through coordinated interactions.

Dickey CA, Koren J, Zhang YJ, Xu YF, Jinwal UK, Birnbaum MJ, Monks B, Sun M, Cheng JQ, Patterson C, Bailey RM, Dunmore J, Soresh S, Leon C, Morgan D, Petrucelli L.

Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3622-7. doi: 10.1073/pnas.0709180105. Epub 2008 Feb 21.

10.

The GSK3 hypothesis of Alzheimer's disease.

Hooper C, Killick R, Lovestone S.

J Neurochem. 2008 Mar;104(6):1433-9. Epub 2007 Dec 18. Review.

11.

Transforming growth factor-beta activation in the lung: focus on fibrosis and reactive oxygen species.

Koli K, Myllärniemi M, Keski-Oja J, Kinnula VL.

Antioxid Redox Signal. 2008 Feb;10(2):333-42. Review.

PMID:
17961070
12.

Analysis of mechanistic pathway models in drug discovery: p38 pathway.

Hendriks BS, Hua F, Chabot JR.

Biotechnol Prog. 2008 Jan-Feb;24(1):96-109. Epub 2007 Oct 5.

PMID:
17918858
13.
14.

Brain CHIP: removing the culprits in neurodegenerative disease.

Dickey CA, Patterson C, Dickson D, Petrucelli L.

Trends Mol Med. 2007 Jan;13(1):32-8. Epub 2006 Nov 28. Review.

PMID:
17127096
15.

A century-old debate on protein aggregation and neurodegeneration enters the clinic.

Lansbury PT, Lashuel HA.

Nature. 2006 Oct 19;443(7113):774-9. Review.

PMID:
17051203
16.

COPASI--a COmplex PAthway SImulator.

Hoops S, Sahle S, Gauges R, Lee C, Pahle J, Simus N, Singhal M, Xu L, Mendes P, Kummer U.

Bioinformatics. 2006 Dec 15;22(24):3067-74. Epub 2006 Oct 10.

17.

Age-related changes in glutathione and glutathione-related enzymes in rat brain.

Zhu Y, Carvey PM, Ling Z.

Brain Res. 2006 May 23;1090(1):35-44. Epub 2006 May 2.

18.

BioModels Database: a free, centralized database of curated, published, quantitative kinetic models of biochemical and cellular systems.

Le Novère N, Bornstein B, Broicher A, Courtot M, Donizelli M, Dharuri H, Li L, Sauro H, Schilstra M, Shapiro B, Snoep JL, Hucka M.

Nucleic Acids Res. 2006 Jan 1;34(Database issue):D689-91.

19.

Hsp90 potentiates the rapid evolution of new traits: drug resistance in diverse fungi.

Cowen LE, Lindquist S.

Science. 2005 Sep 30;309(5744):2185-9.

20.

Differential patterns of apoptosis in response to aging in Drosophila.

Zheng J, Edelman SW, Tharmarajah G, Walker DW, Pletcher SD, Seroude L.

Proc Natl Acad Sci U S A. 2005 Aug 23;102(34):12083-8. Epub 2005 Aug 12.

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