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Items: 18

1.

CX-4945, an orally bioavailable selective inhibitor of protein kinase CK2, inhibits prosurvival and angiogenic signaling and exhibits antitumor efficacy.

Siddiqui-Jain A, Drygin D, Streiner N, Chua P, Pierre F, O'Brien SE, Bliesath J, Omori M, Huser N, Ho C, Proffitt C, Schwaebe MK, Ryckman DM, Rice WG, Anderes K.

Cancer Res. 2010 Dec 15;70(24):10288-98. doi: 10.1158/0008-5472.CAN-10-1893.

2.

Casein Kinase II: an attractive target for anti-cancer drug design.

Hanif IM, Hanif IM, Shazib MA, Ahmad KA, Pervaiz S.

Int J Biochem Cell Biol. 2010 Oct;42(10):1602-5. doi: 10.1016/j.biocel.2010.06.010. Epub 2010 Jun 15. Review.

PMID:
20558317
3.

Emergence of protein kinase CK2 as a key target in cancer therapy.

Trembley JH, Chen Z, Unger G, Slaton J, Kren BT, Van Waes C, Ahmed K.

Biofactors. 2010 May-Jun;36(3):187-95. doi: 10.1002/biof.96. Review.

4.

Extraordinary pleiotropy of protein kinase CK2 revealed by weblogo phosphoproteome analysis.

Salvi M, Sarno S, Cesaro L, Nakamura H, Pinna LA.

Biochim Biophys Acta. 2009 May;1793(5):847-59. doi: 10.1016/j.bbamcr.2009.01.013. Epub 2009 Jan 31.

5.

Protein kinase CK2 as a druggable target.

Sarno S, Pinna LA.

Mol Biosyst. 2008 Sep;4(9):889-94. doi: 10.1039/b805534c. Epub 2008 Jun 12. Review.

PMID:
18704226
6.

Protein kinase CK2 in human diseases.

Guerra B, Issinger OG.

Curr Med Chem. 2008;15(19):1870-86. Review.

PMID:
18691045
7.

The regulatory beta subunit of protein kinase CK2 contributes to the recognition of the substrate consensus sequence. A study with an eIF2 beta-derived peptide.

Poletto G, Vilardell J, Marin O, Pagano MA, Cozza G, Sarno S, Falqués A, Itarte E, Pinna LA, Meggio F.

Biochemistry. 2008 Aug 12;47(32):8317-25. doi: 10.1021/bi800216d. Epub 2008 Jul 18.

PMID:
18636746
8.

Gene targeting of CK2 catalytic subunits.

Seldin DC, Lou DY, Toselli P, Landesman-Bollag E, Dominguez I.

Mol Cell Biochem. 2008 Sep;316(1-2):141-7. doi: 10.1007/s11010-008-9811-8. Epub 2008 Jul 2.

9.

The alpha catalytic subunit of protein kinase CK2 is required for mouse embryonic development.

Lou DY, Dominguez I, Toselli P, Landesman-Bollag E, O'Brien C, Seldin DC.

Mol Cell Biol. 2008 Jan;28(1):131-9. Epub 2007 Oct 22.

10.

Too much of a good thing: the role of protein kinase CK2 in tumorigenesis and prospects for therapeutic inhibition of CK2.

Duncan JS, Litchfield DW.

Biochim Biophys Acta. 2008 Jan;1784(1):33-47. Epub 2007 Aug 30. Review.

PMID:
17931986
11.

Identifying interaction motifs in CK2beta--a ubiquitous kinase regulatory subunit.

Bolanos-Garcia VM, Fernandez-Recio J, Allende JE, Blundell TL.

Trends Biochem Sci. 2006 Dec;31(12):654-61. Epub 2006 Nov 3.

PMID:
17084631
12.

One-thousand-and-one substrates of protein kinase CK2?

Meggio F, Pinna LA.

FASEB J. 2003 Mar;17(3):349-68. Review.

PMID:
12631575
13.
14.

Phosphorylation regulates the stability of the regulatory CK2beta subunit.

Zhang C, Vilk G, Canton DA, Litchfield DW.

Oncogene. 2002 May 23;21(23):3754-64.

15.

Protein kinase CK2 in mammary gland tumorigenesis.

Landesman-Bollag E, Romieu-Mourez R, Song DH, Sonenshein GE, Cardiff RD, Seldin DC.

Oncogene. 2001 May 31;20(25):3247-57.

16.

Globozoospermia in mice lacking the casein kinase II alpha' catalytic subunit.

Xu X, Toselli PA, Russell LD, Seldin DC.

Nat Genet. 1999 Sep;23(1):118-21.

PMID:
10471512
17.
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