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Items: 1 to 20 of 59

1.

Differential signaling of the endogenous agonists at the beta2-adrenergic receptor.

Reiner S, Ambrosio M, Hoffmann C, Lohse MJ.

J Biol Chem. 2010 Nov 12;285(46):36188-98. doi: 10.1074/jbc.M110.175604. Epub 2010 Sep 13.

2.

Regulation of AMPA receptor channels and synaptic plasticity by cofilin phosphatase Slingshot in cortical neurons.

Yuen EY, Liu W, Kafri T, van Praag H, Yan Z.

J Physiol. 2010 Jul 1;588(Pt 13):2361-71. doi: 10.1113/jphysiol.2009.186353. Epub 2010 May 4.

3.

Teaching old receptors new tricks: biasing seven-transmembrane receptors.

Rajagopal S, Rajagopal K, Lefkowitz RJ.

Nat Rev Drug Discov. 2010 May;9(5):373-86. doi: 10.1038/nrd3024. Review.

4.

Binding of amyloid beta peptide to beta2 adrenergic receptor induces PKA-dependent AMPA receptor hyperactivity.

Wang D, Govindaiah G, Liu R, De Arcangelis V, Cox CL, Xiang YK.

FASEB J. 2010 Sep;24(9):3511-21. doi: 10.1096/fj.10-156661. Epub 2010 Apr 15.

5.

Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine.

Heneka MT, Nadrigny F, Regen T, Martinez-Hernandez A, Dumitrescu-Ozimek L, Terwel D, Jardanhazi-Kurutz D, Walter J, Kirchhoff F, Hanisch UK, Kummer MP.

Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):6058-63. doi: 10.1073/pnas.0909586107. Epub 2010 Mar 15.

6.

The year in G protein-coupled receptor research.

Millar RP, Newton CL.

Mol Endocrinol. 2010 Jan;24(1):261-74. doi: 10.1210/me.2009-0473. Epub 2009 Dec 17. Review.

7.

Assembly of a beta2-adrenergic receptor--GluR1 signalling complex for localized cAMP signalling.

Joiner ML, Lisé MF, Yuen EY, Kam AY, Zhang M, Hall DD, Malik ZA, Qian H, Chen Y, Ulrich JD, Burette AC, Weinberg RJ, Law PY, El-Husseini A, Yan Z, Hell JW.

EMBO J. 2010 Jan 20;29(2):482-95. doi: 10.1038/emboj.2009.344. Epub 2009 Nov 26.

8.

Arrestin orchestrates crosstalk between G protein-coupled receptors to modulate the spatiotemporal activation of ERK MAPK.

Cervantes D, Crosby C, Xiang Y.

Circ Res. 2010 Jan 8;106(1):79-88. doi: 10.1161/CIRCRESAHA.109.198580. Epub 2009 Nov 19.

9.

Agonist dose-dependent phosphorylation by protein kinase A and G protein-coupled receptor kinase regulates beta2 adrenoceptor coupling to G(i) proteins in cardiomyocytes.

Liu R, Ramani B, Soto D, De Arcangelis V, Xiang Y.

J Biol Chem. 2009 Nov 20;284(47):32279-87. doi: 10.1074/jbc.M109.021428. Epub 2009 Aug 25.

10.

Dynamic protein kinase a activities induced by beta-adrenoceptors dictate signaling propagation for substrate phosphorylation and myocyte contraction.

Soto D, De Arcangelis V, Zhang J, Xiang Y.

Circ Res. 2009 Mar 27;104(6):770-9. doi: 10.1161/CIRCRESAHA.108.187880. Epub 2009 Feb 12.

11.

The locus coeruleus and noradrenergic modulation of cognition.

Sara SJ.

Nat Rev Neurosci. 2009 Mar;10(3):211-23. doi: 10.1038/nrn2573. Epub 2009 Feb 4. Review.

PMID:
19190638
12.

Effects of cardiovascular medications on rate of functional decline in Alzheimer disease.

Rosenberg PB, Mielke MM, Tschanz J, Cook L, Corcoran C, Hayden KM, Norton M, Rabins PV, Green RC, Welsh-Bohmer KA, Breitner JC, Munger R, Lyketsos CG.

Am J Geriatr Psychiatry. 2008 Nov;16(11):883-92. doi: 10.1097/JGP.0b013e318181276a.

13.

Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease.

Busche MA, Eichhoff G, Adelsberger H, Abramowski D, Wiederhold KH, Haass C, Staufenbiel M, Konnerth A, Garaschuk O.

Science. 2008 Sep 19;321(5896):1686-9. doi: 10.1126/science.1162844.

14.
15.

Polymorphisms at the beta2-adrenergic receptor gene influence Alzheimer's disease susceptibility.

Yu JT, Tan L, Ou JR, Zhu JX, Liu K, Song JH, Sun YP.

Brain Res. 2008 May 19;1210:216-22. doi: 10.1016/j.brainres.2008.03.019. Epub 2008 Mar 20.

PMID:
18423577
16.

Amyloid beta protein dimer-containing human CSF disrupts synaptic plasticity: prevention by systemic passive immunization.

Klyubin I, Betts V, Welzel AT, Blennow K, Zetterberg H, Wallin A, Lemere CA, Cullen WK, Peng Y, Wisniewski T, Selkoe DJ, Anwyl R, Walsh DM, Rowan MJ.

J Neurosci. 2008 Apr 16;28(16):4231-7. doi: 10.1523/JNEUROSCI.5161-07.2008.

17.

A molecular pathway of neurodegeneration linking alpha-synuclein to ApoE and Abeta peptides.

Gallardo G, Schlüter OM, Südhof TC.

Nat Neurosci. 2008 Mar;11(3):301-8. doi: 10.1038/nn2058. Epub 2008 Feb 24.

PMID:
18297066
18.

beta-arrestin-biased agonism at the beta2-adrenergic receptor.

Drake MT, Violin JD, Whalen EJ, Wisler JW, Shenoy SK, Lefkowitz RJ.

J Biol Chem. 2008 Feb 29;283(9):5669-76. Epub 2007 Dec 17.

19.

Norepinephrine- and epinephrine-induced distinct beta2-adrenoceptor signaling is dictated by GRK2 phosphorylation in cardiomyocytes.

Wang Y, De Arcangelis V, Gao X, Ramani B, Jung YS, Xiang Y.

J Biol Chem. 2008 Jan 25;283(4):1799-807. Epub 2007 Dec 3.

20.

beta2-adrenergic receptor signaling and desensitization elucidated by quantitative modeling of real time cAMP dynamics.

Violin JD, DiPilato LM, Yildirim N, Elston TC, Zhang J, Lefkowitz RJ.

J Biol Chem. 2008 Feb 1;283(5):2949-61. Epub 2007 Nov 28.

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