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Items: 1 to 20 of 34

1.

Mapping the ligand-binding site on a G protein-coupled receptor (GPCR) using genetically encoded photocrosslinkers.

Grunbeck A, Huber T, Sachdev P, Sakmar TP.

Biochemistry. 2011 May 3;50(17):3411-3. doi: 10.1021/bi200214r.

2.

NMR structure of the first extracellular domain of corticotropin-releasing factor receptor 1 (ECD1-CRF-R1) complexed with a high affinity agonist.

Grace CR, Perrin MH, Gulyas J, Rivier JE, Vale WW, Riek R.

J Biol Chem. 2010 Dec 3;285(49):38580-9. doi: 10.1074/jbc.M110.121897.

3.

Adding new chemistries to the genetic code.

Liu CC, Schultz PG.

Annu Rev Biochem. 2010;79:413-44. doi: 10.1146/annurev.biochem.052308.105824. Review.

PMID:
20307192
4.

The amino-terminus of angiotensin II contacts several ectodomains of the angiotensin II receptor AT1.

Fillion D, Lemieux G, Basambombo LL, Lavigne P, Guillemette G, Leduc R, Escher E.

J Med Chem. 2010 Mar 11;53(5):2063-75. doi: 10.1021/jm9015747.

PMID:
20146480
5.

Impact of nonnatural amino acid mutagenesis on the in vivo function and binding modes of a transcriptional activator.

Majmudar CY, Lee LW, Lancia JK, Nwokoye A, Wang Q, Wands AM, Wang L, Mapp AK.

J Am Chem Soc. 2009 Oct 14;131(40):14240-2. doi: 10.1021/ja904378z.

6.

Improving orthogonal tRNA-synthetase recognition for efficient unnatural amino acid incorporation and application in mammalian cells.

Takimoto JK, Adams KL, Xiang Z, Wang L.

Mol Biosyst. 2009 Sep;5(9):931-4. doi: 10.1039/b904228h.

PMID:
19668857
7.

Passing the baton in class B GPCRs: peptide hormone activation via helix induction?

Parthier C, Reedtz-Runge S, Rudolph R, Stubbs MT.

Trends Biochem Sci. 2009 Jun;34(6):303-10. doi: 10.1016/j.tibs.2009.02.004. Review.

PMID:
19446460
8.

FTIR analysis of GPCR activation using azido probes.

Ye S, Huber T, Vogel R, Sakmar TP.

Nat Chem Biol. 2009 Jun;5(6):397-9. doi: 10.1038/nchembio.167.

9.

Expanding the genetic code for biological studies.

Wang Q, Parrish AR, Wang L.

Chem Biol. 2009 Mar 27;16(3):323-36. doi: 10.1016/j.chembiol.2009.03.001. Review.

10.

Residue 17 of sauvagine cross-links to the first transmembrane domain of corticotropin-releasing factor receptor 1 (CRFR1).

Assil-Kishawi I, Samra TA, Mierke DF, Abou-Samra AB.

J Biol Chem. 2008 Dec 19;283(51):35644-51. doi: 10.1074/jbc.M806351200.

11.

Molecular recognition of corticotropin-releasing factor by its G-protein-coupled receptor CRFR1.

Pioszak AA, Parker NR, Suino-Powell K, Xu HE.

J Biol Chem. 2008 Nov 21;283(47):32900-12. doi: 10.1074/jbc.M805749200.

12.

Unnatural amino acid replacement in a yeast G protein-coupled receptor in its native environment.

Huang LY, Umanah G, Hauser M, Son C, Arshava B, Naider F, Becker JM.

Biochemistry. 2008 May 20;47(20):5638-48. doi: 10.1021/bi701866e.

PMID:
18419133
13.

Site-specific incorporation of keto amino acids into functional G protein-coupled receptors using unnatural amino acid mutagenesis.

Ye S, Köhrer C, Huber T, Kazmi M, Sachdev P, Yan EC, Bhagat A, RajBhandary UL, Sakmar TP.

J Biol Chem. 2008 Jan 18;283(3):1525-33.

14.

Structural basis of natural ligand binding and activation of the Class II G-protein-coupled secretin receptor.

Miller LJ, Dong M, Harikumar KG, Gao F.

Biochem Soc Trans. 2007 Aug;35(Pt 4):709-12. Review.

PMID:
17635130
15.

Genetically encoding unnatural amino acids for cellular and neuronal studies.

Wang W, Takimoto JK, Louie GV, Baiga TJ, Noel JP, Lee KF, Slesinger PA, Wang L.

Nat Neurosci. 2007 Aug;10(8):1063-72.

16.

Achieving signalling selectivity of ligands for the corticotropin-releasing factor type 1 receptor by modifying the agonist's signalling domain.

Beyermann M, Heinrich N, Fechner K, Furkert J, Zhang W, Kraetke O, Bienert M, Berger H.

Br J Pharmacol. 2007 Jul;151(6):851-9.

17.
18.

Dimerization of corticotropin-releasing factor receptor type 1 is not coupled to ligand binding.

Kraetke O, Wiesner B, Eichhorst J, Furkert J, Bienert M, Beyermann M.

J Recept Signal Transduct Res. 2005;25(4-6):251-76.

PMID:
16393915
19.

Photoaffinity cross-linking of the corticotropin-releasing factor receptor type 1 with photoreactive urocortin analogues.

Kraetke O, Holeran B, Berger H, Escher E, Bienert M, Beyermann M.

Biochemistry. 2005 Nov 29;44(47):15569-77.

PMID:
16300406
20.

The signal peptide of the rat corticotropin-releasing factor receptor 1 promotes receptor expression but is not essential for establishing a functional receptor.

Alken M, Rutz C, Köchl R, Donalies U, Oueslati M, Furkert J, Wietfeld D, Hermosilla R, Scholz A, Beyermann M, Rosenthal W, Schülein R.

Biochem J. 2005 Sep 1;390(Pt 2):455-64.

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