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Evidence of endothelial progenitor cells in the human brain and spinal cord arteriovenous malformations.

Gao P, Chen Y, Lawton MT, Barbaro NM, Yang GY, Su H, Ling F, Young WL.

Neurosurgery. 2010 Oct;67(4):1029-35. doi: 10.1227/NEU.0b013e3181ecc49e.


VEGF Induces More Severe Cerebrovascular Dysplasia in Endoglin than in Alk1 Mice.

Hao Q, Zhu Y, Su H, Shen F, Yang GY, Kim H, Young WL.

Transl Stroke Res. 2010 Sep 1;1(3):197-201.


The role of complement Factor H in age-related macular degeneration: a review.

Donoso LA, Vrabec T, Kuivaniemi H.

Surv Ophthalmol. 2010 May-Jun;55(3):227-46. doi: 10.1016/j.survophthal.2009.11.001. Review.


Thalidomide stimulates vessel maturation and reduces epistaxis in individuals with hereditary hemorrhagic telangiectasia.

Lebrin F, Srun S, Raymond K, Martin S, van den Brink S, Freitas C, Bréant C, Mathivet T, Larrivée B, Thomas JL, Arthur HM, Westermann CJ, Disch F, Mager JJ, Snijder RJ, Eichmann A, Mummery CL.

Nat Med. 2010 Apr;16(4):420-8. doi: 10.1038/nm.2131. Epub 2010 Apr 4.


Pathogenesis of arteriovenous malformations in the absence of endoglin.

Mahmoud M, Allinson KR, Zhai Z, Oakenfull R, Ghandi P, Adams RH, Fruttiger M, Arthur HM.

Circ Res. 2010 Apr 30;106(8):1425-33. doi: 10.1161/CIRCRESAHA.109.211037. Epub 2010 Mar 11.


Notch1 activation in mice causes arteriovenous malformations phenocopied by ephrinB2 and EphB4 mutants.

Krebs LT, Starling C, Chervonsky AV, Gridley T.

Genesis. 2010 Mar;48(3):146-50. doi: 10.1002/dvg.20599.


EPHB4 gene polymorphisms and risk of intracranial hemorrhage in patients with brain arteriovenous malformations.

Weinsheimer S, Kim H, Pawlikowska L, Chen Y, Lawton MT, Sidney S, Kwok PY, McCulloch CE, Young WL.

Circ Cardiovasc Genet. 2009 Oct;2(5):476-82. doi: 10.1161/CIRCGENETICS.109.883595. Epub 2009 Aug 22.


Ten-year detection rate of brain arteriovenous malformations in a large, multiethnic, defined population.

Gabriel RA, Kim H, Sidney S, McCulloch CE, Singh V, Johnston SC, Ko NU, Achrol AS, Zaroff JG, Young WL.

Stroke. 2010 Jan;41(1):21-6. doi: 10.1161/STROKEAHA.109.566018. Epub 2009 Nov 19.


Notch-1 signalling is activated in brain arteriovenous malformations in humans.

ZhuGe Q, Zhong M, Zheng W, Yang GY, Mao X, Xie L, Chen G, Chen Y, Lawton MT, Young WL, Greenberg DA, Jin K.

Brain. 2009 Dec;132(Pt 12):3231-41. doi: 10.1093/brain/awp246.


Real-time imaging of de novo arteriovenous malformation in a mouse model of hereditary hemorrhagic telangiectasia.

Park SO, Wankhede M, Lee YJ, Choi EJ, Fliess N, Choe SW, Oh SH, Walter G, Raizada MK, Sorg BS, Oh SP.

J Clin Invest. 2009 Nov;119(11):3487-96. doi: 10.1172/JCI39482. Epub 2009 Oct 1.


Gene expression patterns in peripheral blood correlate with the extent of coronary artery disease.

Sinnaeve PR, Donahue MP, Grass P, Seo D, Vonderscher J, Chibout SD, Kraus WE, Sketch M Jr, Nelson C, Ginsburg GS, Goldschmidt-Clermont PJ, Granger CB.

PLoS One. 2009 Sep 14;4(9):e7037. doi: 10.1371/journal.pone.0007037.


Endothelial Notch signaling is upregulated in human brain arteriovenous malformations and a mouse model of the disease.

Murphy PA, Lu G, Shiah S, Bollen AW, Wang RA.

Lab Invest. 2009 Sep;89(9):971-82. doi: 10.1038/labinvest.2009.62. Epub 2009 Jun 22. Erratum in: Lab Invest. 2009 Sep;89(9):1071.


Roles of matrix metalloproteinases in flow-induced outward vascular remodeling.

Ota R, Kurihara C, Tsou TL, Young WL, Yeghiazarians Y, Chang M, Mobashery S, Sakamoto A, Hashimoto T.

J Cereb Blood Flow Metab. 2009 Sep;29(9):1547-58. doi: 10.1038/jcbfm.2009.77. Epub 2009 Jun 10.


Gene expression profiling of peripheral blood in patients with abdominal aortic aneurysm.

Giusti B, Rossi L, Lapini I, Magi A, Pratesi G, Lavitrano M, Biasi GM, Pulli R, Pratesi C, Abbate R.

Eur J Vasc Endovasc Surg. 2009 Jul;38(1):104-12. doi: 10.1016/j.ejvs.2009.01.020. Epub 2009 Feb 23.


Common variants in interleukin-1-Beta gene are associated with intracranial hemorrhage and susceptibility to brain arteriovenous malformation.

Kim H, Hysi PG, Pawlikowska L, Poon A, Burchard EG, Zaroff JG, Sidney S, Ko NU, Achrol AS, Lawton MT, McCulloch CE, Kwok PY, Young WL.

Cerebrovasc Dis. 2009;27(2):176-82. doi: 10.1159/000185609. Epub 2008 Dec 18.


Genetic considerations relevant to intracranial hemorrhage and brain arteriovenous malformations.

Kim H, Marchuk DA, Pawlikowska L, Chen Y, Su H, Yang GY, Young WL.

Acta Neurochir Suppl. 2008;105:199-206. Review.


Development of a cerebral microvascular dysplasia model in rodents.

Su H, Hao Q, Shen F, Zhu Y, Lee CZ, Young WL, Yang GY.

Acta Neurochir Suppl. 2008;105:185-9. Review.


Roles of macrophages in flow-induced outward vascular remodeling.

Nuki Y, Matsumoto MM, Tsang E, Young WL, van Rooijen N, Kurihara C, Hashimoto T.

J Cereb Blood Flow Metab. 2009 Mar;29(3):495-503. doi: 10.1038/jcbfm.2008.136. Epub 2008 Nov 12.


Increased tissue perfusion promotes capillary dysplasia in the ALK1-deficient mouse brain following VEGF stimulation.

Hao Q, Su H, Marchuk DA, Rola R, Wang Y, Liu W, Young WL, Yang GY.

Am J Physiol Heart Circ Physiol. 2008 Dec;295(6):H2250-6. doi: 10.1152/ajpheart.00083.2008. Epub 2008 Oct 3.


Evidence of inflammatory cell involvement in brain arteriovenous malformations.

Chen Y, Zhu W, Bollen AW, Lawton MT, Barbaro NM, Dowd CF, Hashimoto T, Yang GY, Young WL.

Neurosurgery. 2008 Jun;62(6):1340-9; discussion 1349-50. doi: 10.1227/01.neu.0000333306.64683.b5.

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