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Items: 1 to 20 of 39


Modulation of angiotensin II-mediated cardiac remodeling by the MEF2A target gene Xirp2.

McCalmon SA, Desjardins DM, Ahmad S, Davidoff KS, Snyder CM, Sato K, Ohashi K, Kielbasa OM, Mathew M, Ewen EP, Walsh K, Gavras H, Naya FJ.

Circ Res. 2010 Mar 19;106(5):952-60. doi: 10.1161/CIRCRESAHA.109.209007. Epub 2010 Jan 21.


Bim-targeted cancer therapy: a link between drug action and underlying molecular changes.

Akiyama T, Dass CR, Choong PF.

Mol Cancer Ther. 2009 Dec;8(12):3173-80. doi: 10.1158/1535-7163.MCT-09-0685. Review.


Genome-wide analysis of MEF2 transcriptional program reveals synaptic target genes and neuronal activity-dependent polyadenylation site selection.

Flavell SW, Kim TK, Gray JM, Harmin DA, Hemberg M, Hong EJ, Markenscoff-Papadimitriou E, Bear DM, Greenberg ME.

Neuron. 2008 Dec 26;60(6):1022-38. doi: 10.1016/j.neuron.2008.11.029.


Prox1 maintains muscle structure and growth in the developing heart.

Risebro CA, Searles RG, Melville AA, Ehler E, Jina N, Shah S, Pallas J, Hubank M, Dillard M, Harvey NL, Schwartz RJ, Chien KR, Oliver G, Riley PR.

Development. 2009 Feb;136(3):495-505. doi: 10.1242/dev.030007. Epub 2008 Dec 17. Erratum in: Development. 2009 Feb;136(4):699.


From synapse to nucleus: calcium-dependent gene transcription in the control of synapse development and function.

Greer PL, Greenberg ME.

Neuron. 2008 Sep 25;59(6):846-60. doi: 10.1016/j.neuron.2008.09.002. Review.


Cardiac developmental defects and eccentric right ventricular hypertrophy in cardiomyocyte focal adhesion kinase (FAK) conditional knockout mice.

Peng X, Wu X, Druso JE, Wei H, Park AY, Kraus MS, Alcaraz A, Chen J, Chien S, Cerione RA, Guan JL.

Proc Natl Acad Sci U S A. 2008 May 6;105(18):6638-43. doi: 10.1073/pnas.0802319105. Epub 2008 Apr 30.


The MEF2D transcription factor mediates stress-dependent cardiac remodeling in mice.

Kim Y, Phan D, van Rooij E, Wang DZ, McAnally J, Qi X, Richardson JA, Hill JA, Bassel-Duby R, Olson EN.

J Clin Invest. 2008 Jan;118(1):124-32.


Regulation of skeletal muscle sarcomere integrity and postnatal muscle function by Mef2c.

Potthoff MJ, Arnold MA, McAnally J, Richardson JA, Bassel-Duby R, Olson EN.

Mol Cell Biol. 2007 Dec;27(23):8143-51. Epub 2007 Sep 17.


Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers.

Potthoff MJ, Wu H, Arnold MA, Shelton JM, Backs J, McAnally J, Richardson JA, Bassel-Duby R, Olson EN.

J Clin Invest. 2007 Sep;117(9):2459-67.


Mef2s are required for thick filament formation in nascent muscle fibres.

Hinits Y, Hughes SM.

Development. 2007 Jul;134(13):2511-9. Epub 2007 May 30.


Myomaxin is a novel transcriptional target of MEF2A that encodes a Xin-related alpha-actinin-interacting protein.

Huang HT, Brand OM, Mathew M, Ignatiou C, Ewen EP, McCalmon SA, Naya FJ.

J Biol Chem. 2006 Dec 22;281(51):39370-9. Epub 2006 Oct 17.


From the membrane to the nucleus and back again: bifunctional focal adhesion proteins.

Hervy M, Hoffman L, Beckerle MC.

Curr Opin Cell Biol. 2006 Oct;18(5):524-32. Epub 2006 Sep 5. Review.


Mechanical stress-strain sensors embedded in cardiac cytoskeleton: Z disk, titin, and associated structures.

Hoshijima M.

Am J Physiol Heart Circ Physiol. 2006 Apr;290(4):H1313-25. Review.


Focal adhesion kinase is essential for costamerogenesis in cultured skeletal muscle cells.

Quach NL, Rando TA.

Dev Biol. 2006 May 1;293(1):38-52. Epub 2006 Mar 13.


A calcium-regulated MEF2 sumoylation switch controls postsynaptic differentiation.

Shalizi A, Gaudillière B, Yuan Z, Stegmüller J, Shirogane T, Ge Q, Tan Y, Schulman B, Harper JW, Bonni A.

Science. 2006 Feb 17;311(5763):1012-7.


Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse number.

Flavell SW, Cowan CW, Kim TK, Greer PL, Lin Y, Paradis S, Griffith EC, Hu LS, Chen C, Greenberg ME.

Science. 2006 Feb 17;311(5763):1008-12.


Early growth response-1 in cardiovascular pathobiology.

Khachigian LM.

Circ Res. 2006 Feb 3;98(2):186-91. Review.


Myospryn is a direct transcriptional target for MEF2A that encodes a striated muscle, alpha-actinin-interacting, costamere-localized protein.

Durham JT, Brand OM, Arnold M, Reynolds JG, Muthukumar L, Weiler H, Richardson JA, Naya FJ.

J Biol Chem. 2006 Mar 10;281(10):6841-9. Epub 2006 Jan 3.


The neuroplasticity-associated arc gene is a direct transcriptional target of early growth response (Egr) transcription factors.

Li L, Carter J, Gao X, Whitehead J, Tourtellotte WG.

Mol Cell Biol. 2005 Dec;25(23):10286-300.

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