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Items: 1 to 20 of 32


Retinoid X receptor gamma signaling accelerates CNS remyelination.

Huang JK, Jarjour AA, Oumesmar BN, Kerninon C, Williams A, Krezel W, Kagechika H, Bauer J, Zhao C, Baron-Van Evercooren A, Chambon P, Ffrench-Constant C, Franklin RJM.

Nat Neurosci. 2011 Jan;14(1):45-53. doi: 10.1038/nn.2702. Epub 2010 Dec 5.


Towards improved animal models of neonatal white matter injury associated with cerebral palsy.

Silbereis JC, Huang EJ, Back SA, Rowitch DH.

Dis Model Mech. 2010 Nov-Dec;3(11-12):678-88. doi: 10.1242/dmm.002915.


Wnt proteins are self-renewal factors for mammary stem cells and promote their long-term expansion in culture.

Zeng YA, Nusse R.

Cell Stem Cell. 2010 Jun 4;6(6):568-77. doi: 10.1016/j.stem.2010.03.020.


Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination.

Zhang Y, Argaw AT, Gurfein BT, Zameer A, Snyder BJ, Ge C, Lu QR, Rowitch DH, Raine CS, Brosnan CF, John GR.

Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):19162-7. doi: 10.1073/pnas.0902834106. Epub 2009 Oct 23.


Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling.

Huang SM, Mishina YM, Liu S, Cheung A, Stegmeier F, Michaud GA, Charlat O, Wiellette E, Zhang Y, Wiessner S, Hild M, Shi X, Wilson CJ, Mickanin C, Myer V, Fazal A, Tomlinson R, Serluca F, Shao W, Cheng H, Shultz M, Rau C, Schirle M, Schlegl J, Ghidelli S, Fawell S, Lu C, Curtis D, Kirschner MW, Lengauer C, Finan PM, Tallarico JA, Bouwmeester T, Porter JA, Bauer A, Cong F.

Nature. 2009 Oct 1;461(7264):614-20. doi: 10.1038/nature08356. Epub 2009 Sep 16.


Axin2 regulates chondrocyte maturation and axial skeletal development.

Dao DY, Yang X, Flick LM, Chen D, Hilton MJ, O'Keefe RJ.

J Orthop Res. 2010 Jan;28(1):89-95. doi: 10.1002/jor.20954.


Wnt signaling is sufficient to perturb oligodendrocyte maturation.

Feigenson K, Reid M, See J, Crenshaw EB 3rd, Grinspan JB.

Mol Cell Neurosci. 2009 Nov;42(3):255-65. doi: 10.1016/j.mcn.2009.07.010. Epub 2009 Jul 18.


Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelination.

Emery B, Agalliu D, Cahoy JD, Watkins TA, Dugas JC, Mulinyawe SB, Ibrahim A, Ligon KL, Rowitch DH, Barres BA.

Cell. 2009 Jul 10;138(1):172-85. doi: 10.1016/j.cell.2009.04.031.


Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS.

Fancy SP, Baranzini SE, Zhao C, Yuk DI, Irvine KA, Kaing S, Sanai N, Franklin RJ, Rowitch DH.

Genes Dev. 2009 Jul 1;23(13):1571-85. doi: 10.1101/gad.1806309. Epub 2009 Jun 10.


HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction.

Ye F, Chen Y, Hoang T, Montgomery RL, Zhao XH, Bu H, Hu T, Taketo MM, van Es JH, Clevers H, Hsieh J, Bassel-Duby R, Olson EN, Lu QR.

Nat Neurosci. 2009 Jul;12(7):829-38. doi: 10.1038/nn.2333. Epub 2009 Jun 7.


Extensive remyelination of the CNS leads to functional recovery.

Duncan ID, Brower A, Kondo Y, Curlee JF Jr, Schultz RD.

Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6832-6. doi: 10.1073/pnas.0812500106. Epub 2009 Apr 2. Erratum in: Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):12208. Dosage error in article text.


Distinct stages of myelination regulated by gamma-secretase and astrocytes in a rapidly myelinating CNS coculture system.

Watkins TA, Emery B, Mulinyawe S, Barres BA.

Neuron. 2008 Nov 26;60(4):555-69. doi: 10.1016/j.neuron.2008.09.011.


Multiple sclerosis.

Compston A, Coles A.

Lancet. 2008 Oct 25;372(9648):1502-17. doi: 10.1016/S0140-6736(08)61620-7.


Remyelination in the CNS: from biology to therapy.

Franklin RJ, Ffrench-Constant C.

Nat Rev Neurosci. 2008 Nov;9(11):839-55. doi: 10.1038/nrn2480. Review.


Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network.

Dessaud E, McMahon AP, Briscoe J.

Development. 2008 Aug;135(15):2489-503. doi: 10.1242/dev.009324. Review.


Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis.

Kuhlmann T, Miron V, Cui Q, Wegner C, Antel J, Brück W.

Brain. 2008 Jul;131(Pt 7):1749-58. doi: 10.1093/brain/awn096. Epub 2008 May 30. Erratum in: Brain. 2009 Apr;132(Pt 4):1118. Cuo, Q [corrected to Cui, Q].


Arrested oligodendrocyte lineage maturation in chronic perinatal white matter injury.

Segovia KN, McClure M, Moravec M, Luo NL, Wan Y, Gong X, Riddle A, Craig A, Struve J, Sherman LS, Back SA.

Ann Neurol. 2008 Apr;63(4):520-30. doi: 10.1002/ana.21359.


Pathogenesis of cerebral white matter injury of prematurity.

Khwaja O, Volpe JJ.

Arch Dis Child Fetal Neonatal Ed. 2008 Mar;93(2):F153-61. doi: 10.1136/adc.2006.108837. Review.


Myelin abnormalities without oligodendrocyte loss in periventricular leukomalacia.

Billiards SS, Haynes RL, Folkerth RD, Borenstein NS, Trachtenberg FL, Rowitch DH, Ligon KL, Volpe JJ, Kinney HC.

Brain Pathol. 2008 Apr;18(2):153-63. doi: 10.1111/j.1750-3639.2007.00107.x. Epub 2008 Jan 3.


Neonatal MRI to predict neurodevelopmental outcomes in preterm infants.

Woodward LJ, Anderson PJ, Austin NC, Howard K, Inder TE.

N Engl J Med. 2006 Aug 17;355(7):685-94.

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