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Fyn is induced by Ras/PI3K/Akt signaling and is required for enhanced invasion/migration.

Yadav V, Denning MF.

Mol Carcinog. 2011 May;50(5):346-52. doi: 10.1002/mc.20716. Epub 2010 Dec 10.


KPNA6 (Importin {alpha}7)-mediated nuclear import of Keap1 represses the Nrf2-dependent antioxidant response.

Sun Z, Wu T, Zhao F, Lau A, Birch CM, Zhang DD.

Mol Cell Biol. 2011 May;31(9):1800-11. doi: 10.1128/MCB.05036-11. Epub 2011 Mar 7.


SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner.

Rada P, Rojo AI, Chowdhry S, McMahon M, Hayes JD, Cuadrado A.

Mol Cell Biol. 2011 Mar;31(6):1121-33. doi: 10.1128/MCB.01204-10. Epub 2011 Jan 18.


PI(3)king apart PTEN's role in cancer.

Zhang S, Yu D.

Clin Cancer Res. 2010 Sep 1;16(17):4325-30. doi: 10.1158/1078-0432.CCR-09-2990. Epub 2010 Jul 8. Review.


Antioxidant-induced modification of INrf2 cysteine 151 and PKC-delta-mediated phosphorylation of Nrf2 serine 40 are both required for stabilization and nuclear translocation of Nrf2 and increased drug resistance.

Niture SK, Jain AK, Jaiswal AK.

J Cell Sci. 2009 Dec 15;122(Pt 24):4452-64. doi: 10.1242/jcs.058537. Epub 2009 Nov 17. Erratum in: J Cell Sci. 2010 Jun;123(Pt 11):1969. Retraction in: J Cell Sci. 2017 Feb 15;130(4):816.


Nrf2:INrf2 (Keap1) signaling in oxidative stress.

Kaspar JW, Niture SK, Jaiswal AK.

Free Radic Biol Med. 2009 Nov 1;47(9):1304-9. doi: 10.1016/j.freeradbiomed.2009.07.035. Epub 2009 Aug 7. Review.


Nrf2 signaling and cell survival.

Niture SK, Kaspar JW, Shen J, Jaiswal AK.

Toxicol Appl Pharmacol. 2010 Apr 1;244(1):37-42. doi: 10.1016/j.taap.2009.06.009. Epub 2009 Jun 16. Review.


Disruption of Nrf2 impairs the resolution of hyperoxia-induced acute lung injury and inflammation in mice.

Reddy NM, Kleeberger SR, Kensler TW, Yamamoto M, Hassoun PM, Reddy SP.

J Immunol. 2009 Jun 1;182(11):7264-71. doi: 10.4049/jimmunol.0804248. Erratum in: J Immunol. 2017 May 1;198(9):3755.


Prothymosin-alpha mediates nuclear import of the INrf2/Cul3 Rbx1 complex to degrade nuclear Nrf2.

Niture SK, Jaiswal AK.

J Biol Chem. 2009 May 15;284(20):13856-68. doi: 10.1074/jbc.M808084200. Epub 2009 Mar 11. Retraction in: J Biol Chem. 2017 Feb 3;292(5):2049.


Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte.

Chen PC, Vargas MR, Pani AK, Smeyne RJ, Johnson DA, Kan YW, Johnson JA.

Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2933-8. doi: 10.1073/pnas.0813361106. Epub 2009 Feb 5.


The Nrf2-ARE pathway: an indicator and modulator of oxidative stress in neurodegeneration.

Johnson JA, Johnson DA, Kraft AD, Calkins MJ, Jakel RJ, Vargas MR, Chen PC.

Ann N Y Acad Sci. 2008 Dec;1147:61-9. doi: 10.1196/annals.1427.036. Review.


Functional interference between glycogen synthase kinase-3 beta and the transcription factor Nrf2 in protection against kainate-induced hippocampal cell death.

Rojo AI, Rada P, Egea J, Rosa AO, López MG, Cuadrado A.

Mol Cell Neurosci. 2008 Sep;39(1):125-32. doi: 10.1016/j.mcn.2008.06.007. Epub 2008 Jun 20.


Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in Drosophila.

Sykiotis GP, Bohmann D.

Dev Cell. 2008 Jan;14(1):76-85. doi: 10.1016/j.devcel.2007.12.002.


An auto-regulatory loop between stress sensors INrf2 and Nrf2 controls their cellular abundance.

Lee OH, Jain AK, Papusha V, Jaiswal AK.

J Biol Chem. 2007 Dec 14;282(50):36412-20. Epub 2007 Oct 9.


Src family kinases: regulation of their activities, levels and identification of new pathways.

Ingley E.

Biochim Biophys Acta. 2008 Jan;1784(1):56-65. Epub 2007 Aug 22. Review.


GSK-3beta acts upstream of Fyn kinase in regulation of nuclear export and degradation of NF-E2 related factor 2.

Jain AK, Jaiswal AK.

J Biol Chem. 2007 Jun 1;282(22):16502-10. Epub 2007 Apr 2.


Phosphorylation of tyrosine 568 controls nuclear export of Nrf2.

Jain AK, Jaiswal AK.

J Biol Chem. 2006 Apr 28;281(17):12132-42. Epub 2006 Mar 2. Retraction in: J Biol Chem. 2017 Feb 3;292(5):2051.


Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer.

Padmanabhan B, Tong KI, Ohta T, Nakamura Y, Scharlock M, Ohtsuji M, Kang MI, Kobayashi A, Yokoyama S, Yamamoto M.

Mol Cell. 2006 Mar 3;21(5):689-700.


Activation of the Nrf2-ARE signaling pathway: a promising strategy in cancer prevention.

Giudice A, Montella M.

Bioessays. 2006 Feb;28(2):169-81. Review.


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