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SerpinB2 deficiency modulates Th1⁄Th2 responses after schistosome infection.

Schroder WA, Gardner J, Le TT, Duke M, Burke ML, Jones MK, McManus DP, Suhrbier A.

Parasite Immunol. 2010 Nov-Dec;32(11-12):764-8.


Effects of interleukin-13 blockade on allergen-induced airway responses in mild atopic asthma.

Gauvreau GM, Boulet LP, Cockcroft DW, Fitzgerald JM, Carlsten C, Davis BE, Deschesnes F, Duong M, Durn BL, Howie KJ, Hui L, Kasaian MT, Killian KJ, Strinich TX, Watson RM, Y N, Zhou S, Raible D, O'Byrne PM.

Am J Respir Crit Care Med. 2011 Apr 15;183(8):1007-14. doi: 10.1164/rccm.201008-1210OC.


Pathophysiology of bronchial smooth muscle remodelling in asthma.

Bara I, Ozier A, Tunon de Lara JM, Marthan R, Berger P.

Eur Respir J. 2010 Nov;36(5):1174-84. doi: 10.1183/09031936.00019810. Review.


A novel subset of CD4(+) T(H)2 memory/effector cells that produce inflammatory IL-17 cytokine and promote the exacerbation of chronic allergic asthma.

Wang YH, Voo KS, Liu B, Chen CY, Uygungil B, Spoede W, Bernstein JA, Huston DP, Liu YJ.

J Exp Med. 2010 Oct 25;207(11):2479-91. doi: 10.1084/jem.20101376.


Mast cell phenotype, location, and activation in severe asthma. Data from the Severe Asthma Research Program.

Balzar S, Fajt ML, Comhair SA, Erzurum SC, Bleecker E, Busse WW, Castro M, Gaston B, Israel E, Schwartz LB, Curran-Everett D, Moore CG, Wenzel SE.

Am J Respir Crit Care Med. 2011 Feb 1;183(3):299-309. doi: 10.1164/rccm.201002-0295OC.


An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis.

Berry MP, Graham CM, McNab FW, Xu Z, Bloch SA, Oni T, Wilkinson KA, Banchereau R, Skinner J, Wilkinson RJ, Quinn C, Blankenship D, Dhawan R, Cush JJ, Mejias A, Ramilo O, Kon OM, Pascual V, Banchereau J, Chaussabel D, O'Garra A.

Nature. 2010 Aug 19;466(7309):973-7. doi: 10.1038/nature09247.


Roles of epithelial cell-derived periostin in TGF-beta activation, collagen production, and collagen gel elasticity in asthma.

Sidhu SS, Yuan S, Innes AL, Kerr S, Woodruff PG, Hou L, Muller SJ, Fahy JV.

Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14170-5. doi: 10.1073/pnas.1009426107.


DP(2) receptor antagonists in development.

Norman P.

Expert Opin Investig Drugs. 2010 Aug;19(8):947-61. doi: 10.1517/13543784.2010.500019. Review.


The many paths to asthma: phenotype shaped by innate and adaptive immunity.

Kim HY, DeKruyff RH, Umetsu DT.

Nat Immunol. 2010 Jul;11(7):577-84. doi: 10.1038/ni.1892. Review.


Expression of the T helper 17-associated cytokines IL-17A and IL-17F in asthma and COPD.

Doe C, Bafadhel M, Siddiqui S, Desai D, Mistry V, Rugman P, McCormick M, Woods J, May R, Sleeman MA, Anderson IK, Brightling CE.

Chest. 2010 Nov;138(5):1140-7. doi: 10.1378/chest.09-3058.


Systemically dispersed innate IL-13-expressing cells in type 2 immunity.

Price AE, Liang HE, Sullivan BM, Reinhardt RL, Eisley CJ, Erle DJ, Locksley RM.

Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11489-94. doi: 10.1073/pnas.1003988107.


Accumulation of intraepithelial mast cells with a unique protease phenotype in T(H)2-high asthma.

Dougherty RH, Sidhu SS, Raman K, Solon M, Solberg OD, Caughey GH, Woodruff PG, Fahy JV.

J Allergy Clin Immunol. 2010 May;125(5):1046-1053.e8. doi: 10.1016/j.jaci.2010.03.003.


Therapeutic efficacy of AM156, a novel prostanoid DP2 receptor antagonist, in murine models of allergic rhinitis and house dust mite-induced pulmonary inflammation.

Stebbins KJ, Broadhead AR, Correa LD, Scott JM, Truong YP, Stearns BA, Hutchinson JH, Prasit P, Evans JF, Lorrain DS.

Eur J Pharmacol. 2010 Jul 25;638(1-3):142-9. doi: 10.1016/j.ejphar.2010.04.031.


Gene-expression profiling for rejection surveillance after cardiac transplantation.

Pham MX, Teuteberg JJ, Kfoury AG, Starling RC, Deng MC, Cappola TP, Kao A, Anderson AS, Cotts WG, Ewald GA, Baran DA, Bogaev RC, Elashoff B, Baron H, Yee J, Valantine HA; IMAGE Study Group..

N Engl J Med. 2010 May 20;362(20):1890-900. doi: 10.1056/NEJMoa0912965.


Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes.

Hastie AT, Moore WC, Meyers DA, Vestal PL, Li H, Peters SP, Bleecker ER; National Heart, Lung, and Blood Institute Severe Asthma Research Program..

J Allergy Clin Immunol. 2010 May;125(5):1028-1036.e13. doi: 10.1016/j.jaci.2010.02.008.


Increased serum IL-17 is an independent risk factor for severe asthma.

Agache I, Ciobanu C, Agache C, Anghel M.

Respir Med. 2010 Aug;104(8):1131-7. doi: 10.1016/j.rmed.2010.02.018.


Asthma and allergic inflammation.

Locksley RM.

Cell. 2010 Mar 19;140(6):777-83. doi: 10.1016/j.cell.2010.03.004.


Inflammatory phenotypes in adult asthma: clinical applications.

Gibson PG.

Clin Respir J. 2009 Oct;3(4):198-206. doi: 10.1111/j.1752-699X.2009.00162.x. Review.


Cell type-specific gene expression differences in complex tissues.

Shen-Orr SS, Tibshirani R, Khatri P, Bodian DL, Staedtler F, Perry NM, Hastie T, Sarwal MM, Davis MM, Butte AJ.

Nat Methods. 2010 Apr;7(4):287-9. doi: 10.1038/nmeth.1439.


A genomic approach to human autoimmune diseases.

Pascual V, Chaussabel D, Banchereau J.

Annu Rev Immunol. 2010;28:535-71. doi: 10.1146/annurev-immunol-030409-101221. Review.

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