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Items: 1 to 20 of 44


Cell transformation mediated by the Epstein-Barr virus G protein-coupled receptor BILF1 is dependent on constitutive signaling.

Lyngaa R, Nørregaard K, Kristensen M, Kubale V, Rosenkilde MM, Kledal TN.

Oncogene. 2010 Aug 5;29(31):4388-98. doi: 10.1038/onc.2010.173. Epub 2010 Jun 14.


Finding the right niche: B-cell migration in the early phases of T-dependent antibody responses.

Pereira JP, Kelly LM, Cyster JG.

Int Immunol. 2010 Jun;22(6):413-9. doi: 10.1093/intimm/dxq047. Review.


Teaching old receptors new tricks: biasing seven-transmembrane receptors.

Rajagopal S, Rajagopal K, Lefkowitz RJ.

Nat Rev Drug Discov. 2010 May;9(5):373-86. doi: 10.1038/nrd3024. Review.


Distinct expression and ligand-binding profiles of two constitutively active GPR17 splice variants.

Benned-Jensen T, Rosenkilde MM.

Br J Pharmacol. 2010 Mar;159(5):1092-105. doi: 10.1111/j.1476-5381.2009.00633.x. Epub 2010 Feb 8.


Guidance of B cells by the orphan G protein-coupled receptor EBI2 shapes humoral immune responses.

Gatto D, Paus D, Basten A, Mackay CR, Brink R.

Immunity. 2009 Aug 21;31(2):259-69. doi: 10.1016/j.immuni.2009.06.016. Epub 2009 Jul 16.


Mutant 5-hydroxytryptamine 1A receptor D116A is a receptor activated solely by synthetic ligands with a rich pharmacology.

Cussac D, Palmier C, Finana F, De Vries L, Tardif S, Léger C, Bernois S, Heusler P.

J Pharmacol Exp Ther. 2009 Oct;331(1):222-33. doi: 10.1124/jpet.109.156307. Epub 2009 Jul 15.


EBI2 mediates B cell segregation between the outer and centre follicle.

Pereira JP, Kelly LM, Xu Y, Cyster JG.

Nature. 2009 Aug 27;460(7259):1122-6. doi: 10.1038/nature08226. Epub 2009 Jul 13.


Chapter 8. Activation mechanisms of chemokine receptors.

Jensen PC, Rosenkilde MM.

Methods Enzymol. 2009;461:171-90. doi: 10.1016/S0076-6879(09)05408-1.


Ligand binding and micro-switches in 7TM receptor structures.

Nygaard R, Frimurer TM, Holst B, Rosenkilde MM, Schwartz TW.

Trends Pharmacol Sci. 2009 May;30(5):249-59. doi: 10.1016/ Epub 2009 Apr 16. Review.


beta-Arrestin1 mediates nicotinic acid-induced flushing, but not its antilipolytic effect, in mice.

Walters RW, Shukla AK, Kovacs JJ, Violin JD, DeWire SM, Lam CM, Chen JR, Muehlbauer MJ, Whalen EJ, Lefkowitz RJ.

J Clin Invest. 2009 May;119(5):1312-21. doi: 10.1172/JCI36806. Epub 2009 Apr 6.


Structural motifs of importance for the constitutive activity of the orphan 7TM receptor EBI2: analysis of receptor activation in the absence of an agonist.

Benned-Jensen T, Rosenkilde MM.

Mol Pharmacol. 2008 Oct;74(4):1008-21. doi: 10.1124/mol.108.049676. Epub 2008 Jul 15.


Gene expression profiling of Epstein-Barr virus-positive and -negative monomorphic B-cell posttransplant lymphoproliferative disorders.

Craig FE, Johnson LR, Harvey SA, Nalesnik MA, Luo JH, Bhattacharya SD, Swerdlow SH.

Diagn Mol Pathol. 2007 Sep;16(3):158-68.


Molecular interaction of a potent nonpeptide agonist with the chemokine receptor CCR8.

Jensen PC, Nygaard R, Thiele S, Elder A, Zhu G, Kolbeck R, Ghosh S, Schwartz TW, Rosenkilde MM.

Mol Pharmacol. 2007 Aug;72(2):327-40. Erratum in: Mol Pharmacol. 2008 Aug;74(2):539. Mol Pharmacol. 2007 Oct;72(4):1095.


Human cytomegalovirus-encoded chemokine receptor US28 promotes tumorigenesis.

Maussang D, Verzijl D, van Walsum M, Leurs R, Holl J, Pleskoff O, Michel D, van Dongen GA, Smit MJ.

Proc Natl Acad Sci U S A. 2006 Aug 29;103(35):13068-73. Epub 2006 Aug 21.


Metal ion site engineering indicates a global toggle switch model for seven-transmembrane receptor activation.

Elling CE, Frimurer TM, Gerlach LO, Jorgensen R, Holst B, Schwartz TW.

J Biol Chem. 2006 Jun 23;281(25):17337-46. Epub 2006 Mar 27.


Molecular pharmacological phenotyping of EBI2. An orphan seven-transmembrane receptor with constitutive activity.

Rosenkilde MM, Benned-Jensen T, Andersen H, Holst PJ, Kledal TN, Lüttichau HR, Larsen JK, Christensen JP, Schwartz TW.

J Biol Chem. 2006 May 12;281(19):13199-208. Epub 2006 Mar 15.


Targeting herpesvirus reliance of the chemokine system.

Rosenkilde MM, Kledal TN.

Curr Drug Targets. 2006 Jan;7(1):103-18. Review.


Molecular mechanism of 7TM receptor activation--a global toggle switch model.

Schwartz TW, Frimurer TM, Holst B, Rosenkilde MM, Elling CE.

Annu Rev Pharmacol Toxicol. 2006;46:481-519. Review.


Identification of an agonist-induced conformational change occurring adjacent to the ligand-binding pocket of the M(3) muscarinic acetylcholine receptor.

Han SJ, Hamdan FF, Kim SK, Jacobson KA, Bloodworth LM, Li B, Wess J.

J Biol Chem. 2005 Oct 14;280(41):34849-58. Epub 2005 Aug 10.

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