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Items: 1 to 20 of 47

1.

The regulation of UDP-glucuronosyltransferase genes by tissue-specific and ligand-activated transcription factors.

Mackenzie PI, Hu DG, Gardner-Stephen DA.

Drug Metab Rev. 2010 Feb;42(1):99-109. doi: 10.3109/03602530903209544.

PMID:
20070244
2.

The prevalence of uridine diphosphate-glucuronosyltransferase 1A9 (UGT1A9) gene promoter region single-nucleotide polymorphisms T-275A and C-2152T and its influence on mycophenolic acid pharmacokinetics in stable renal transplant patients.

Sánchez-Fructuoso AI, Maestro ML, Calvo N, Viudarreta M, Pérez-Flores I, Veganzone S, De la Orden V, Ortega D, Arroyo M, Barrientos A.

Transplant Proc. 2009 Jul-Aug;41(6):2313-6. doi: 10.1016/j.transproceed.2009.06.038.

PMID:
19715905
3.

Cruciferous vegetable feeding alters UGT1A1 activity: diet- and genotype-dependent changes in serum bilirubin in a controlled feeding trial.

Navarro SL, Peterson S, Chen C, Makar KW, Schwarz Y, King IB, Li SS, Li L, Kestin M, Lampe JW.

Cancer Prev Res (Phila). 2009 Apr;2(4):345-52. doi: 10.1158/1940-6207.CAPR-08-0178. Epub 2009 Mar 31.

4.

Citrus fruit intake is associated with lower serum bilirubin concentration among women with the UGT1A1*28 polymorphism.

Saracino MR, Bigler J, Schwarz Y, Chang JL, Li S, Li L, White E, Potter JD, Lampe JW.

J Nutr. 2009 Mar;139(3):555-60. doi: 10.3945/jn.108.097279. Epub 2009 Jan 13.

5.

Gender differences in pharmacological response.

Anderson GD.

Int Rev Neurobiol. 2008;83:1-10. doi: 10.1016/S0074-7742(08)00001-9. Review.

PMID:
18929073
7.

Phytochemical regulation of UDP-glucuronosyltransferases: implications for cancer prevention.

Saracino MR, Lampe JW.

Nutr Cancer. 2007;59(2):121-41. Review.

PMID:
18001207
8.

UGT1A1 polymorphism is associated with serum bilirubin concentrations in a randomized, controlled, fruit and vegetable feeding trial.

Chang JL, Bigler J, Schwarz Y, Li SS, Li L, King IB, Potter JD, Lampe JW.

J Nutr. 2007 Apr;137(4):890-7.

9.

Kinetics of acetaminophen glucuronidation by UDP-glucuronosyltransferases 1A1, 1A6, 1A9 and 2B15. Potential implications in acetaminophen-induced hepatotoxicity.

Mutlib AE, Goosen TC, Bauman JN, Williams JA, Kulkarni S, Kostrubsky S.

Chem Res Toxicol. 2006 May;19(5):701-9.

PMID:
16696573
10.

Effect of the UGT2B15 genotype on the pharmacokinetics, pharmacodynamics, and drug interactions of intravenous lorazepam in healthy volunteers.

Chung JY, Cho JY, Yu KS, Kim JR, Jung HR, Lim KS, Jang IJ, Shin SG.

Clin Pharmacol Ther. 2005 Jun;77(6):486-94.

PMID:
15961980
11.

Association of genetic variation in tamoxifen-metabolizing enzymes with overall survival and recurrence of disease in breast cancer patients.

Nowell SA, Ahn J, Rae JM, Scheys JO, Trovato A, Sweeney C, MacLeod SL, Kadlubar FF, Ambrosone CB.

Breast Cancer Res Treat. 2005 Jun;91(3):249-58.

12.

Phenobarbital and phenytoin increased acetaminophen hepatotoxicity due to inhibition of UDP-glucuronosyltransferases in cultured human hepatocytes.

Kostrubsky SE, Sinclair JF, Strom SC, Wood S, Urda E, Stolz DB, Wen YH, Kulkarni S, Mutlib A.

Toxicol Sci. 2005 Sep;87(1):146-55. Epub 2005 Jun 2.

PMID:
15933229
13.

Keap1, the sensor for electrophiles and oxidants that regulates the phase 2 response, is a zinc metalloprotein.

Dinkova-Kostova AT, Holtzclaw WD, Wakabayashi N.

Biochemistry. 2005 May 10;44(18):6889-99.

PMID:
15865434
14.

UDP glucuronosyltransferase (UGT) 1A6 pharmacogenetics: I. Identification of polymorphisms in the 5'-regulatory and exon 1 regions, and association with human liver UGT1A6 gene expression and glucuronidation.

Krishnaswamy S, Hao Q, Al-Rohaimi A, Hesse LM, von Moltke LL, Greenblatt DJ, Court MH.

J Pharmacol Exp Ther. 2005 Jun;313(3):1331-9. Epub 2005 Mar 10.

15.

UDP glucuronosyltransferase (UGT) 1A6 pharmacogenetics: II. Functional impact of the three most common nonsynonymous UGT1A6 polymorphisms (S7A, T181A, and R184S).

Krishnaswamy S, Hao Q, Al-Rohaimi A, Hesse LM, von Moltke LL, Greenblatt DJ, Court MH.

J Pharmacol Exp Ther. 2005 Jun;313(3):1340-6. Epub 2005 Mar 10.

17.

Glucuronidation of acetaminophen is independent of UGT1A1 promotor genotype.

Rauchschwalbe SK, Zühlsdorf MT, Wensing G, Kuhlmann J.

Int J Clin Pharmacol Ther. 2004 Feb;42(2):73-7.

PMID:
15180166
18.

UDP-glucuronosyltransferase (UGT) 2B15 pharmacogenetics: UGT2B15 D85Y genotype and gender are major determinants of oxazepam glucuronidation by human liver.

Court MH, Hao Q, Krishnaswamy S, Bekaii-Saab T, Al-Rohaimi A, von Moltke LL, Greenblatt DJ.

J Pharmacol Exp Ther. 2004 Aug;310(2):656-65. Epub 2004 Mar 25.

19.
20.

Stereoselective conjugation of oxazepam by human UDP-glucuronosyltransferases (UGTs): S-oxazepam is glucuronidated by UGT2B15, while R-oxazepam is glucuronidated by UGT2B7 and UGT1A9.

Court MH, Duan SX, Guillemette C, Journault K, Krishnaswamy S, Von Moltke LL, Greenblatt DJ.

Drug Metab Dispos. 2002 Nov;30(11):1257-65.

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