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Items: 1 to 20 of 58

1.

Brain metastases as preventive and therapeutic targets.

Steeg PS, Camphausen KA, Smith QR.

Nat Rev Cancer. 2011 May;11(5):352-63. doi: 10.1038/nrc3053. Epub 2011 Apr 7. Review.

PMID:
21472002
2.

Inhibition of Notch signaling reduces the stem-like population of breast cancer cells and prevents mammosphere formation.

Grudzien P, Lo S, Albain KS, Robinson P, Rajan P, Strack PR, Golde TE, Miele L, Foreman KE.

Anticancer Res. 2010 Oct;30(10):3853-67.

PMID:
21036696
3.

Heterogeneous blood-tumor barrier permeability determines drug efficacy in experimental brain metastases of breast cancer.

Lockman PR, Mittapalli RK, Taskar KS, Rudraraju V, Gril B, Bohn KA, Adkins CE, Roberts A, Thorsheim HR, Gaasch JA, Huang S, Palmieri D, Steeg PS, Smith QR.

Clin Cancer Res. 2010 Dec 1;16(23):5664-78. doi: 10.1158/1078-0432.CCR-10-1564. Epub 2010 Sep 9.

4.

Targeting Notch to target cancer stem cells.

Pannuti A, Foreman K, Rizzo P, Osipo C, Golde T, Osborne B, Miele L.

Clin Cancer Res. 2010 Jun 15;16(12):3141-52. doi: 10.1158/1078-0432.CCR-09-2823. Epub 2010 Jun 8. Review.

5.

High aldehyde dehydrogenase activity identifies tumor-initiating and metastasis-initiating cells in human prostate cancer.

van den Hoogen C, van der Horst G, Cheung H, Buijs JT, Lippitt JM, Guzmán-Ramírez N, Hamdy FC, Eaton CL, Thalmann GN, Cecchini MG, Pelger RC, van der Pluijm G.

Cancer Res. 2010 Jun 15;70(12):5163-73. doi: 10.1158/0008-5472.CAN-09-3806. Epub 2010 Jun 1.

6.

Cancer stemness and metastasis: therapeutic consequences and perspectives.

Monteiro J, Fodde R.

Eur J Cancer. 2010 May;46(7):1198-203. doi: 10.1016/j.ejca.2010.02.030. Epub 2010 Mar 18. Review.

PMID:
20303259
7.

How the NOTCH pathway contributes to the ability of osteosarcoma cells to metastasize.

Hughes DP.

Cancer Treat Res. 2009;152:479-96. doi: 10.1007/978-1-4419-0284-9_28. Review.

PMID:
20213410
8.

Down-regulation of Notch1 by gamma-secretase inhibition contributes to cell growth inhibition and apoptosis in ovarian cancer cells A2780.

Wang M, Wu L, Wang L, Xin X.

Biochem Biophys Res Commun. 2010 Feb 26;393(1):144-9. doi: 10.1016/j.bbrc.2010.01.103. Epub 2010 Feb 1.

PMID:
20117093
9.

Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor.

Harrison H, Farnie G, Howell SJ, Rock RE, Stylianou S, Brennan KR, Bundred NJ, Clarke RB.

Cancer Res. 2010 Jan 15;70(2):709-18. doi: 10.1158/0008-5472.CAN-09-1681. Epub 2010 Jan 12.

10.

Notch 1 signaling is active in ovarian cancer.

Rose SL, Kunnimalaiyaan M, Drenzek J, Seiler N.

Gynecol Oncol. 2010 Apr;117(1):130-3. doi: 10.1016/j.ygyno.2009.12.003. Epub 2010 Jan 8.

PMID:
20060575
11.

Hypoxia potentiates Notch signaling in breast cancer leading to decreased E-cadherin expression and increased cell migration and invasion.

Chen J, Imanaka N, Chen J, Griffin JD.

Br J Cancer. 2010 Jan 19;102(2):351-60. doi: 10.1038/sj.bjc.6605486. Epub 2009 Dec 15.

12.

Vorinostat inhibits brain metastatic colonization in a model of triple-negative breast cancer and induces DNA double-strand breaks.

Palmieri D, Lockman PR, Thomas FC, Hua E, Herring J, Hargrave E, Johnson M, Flores N, Qian Y, Vega-Valle E, Taskar KS, Rudraraju V, Mittapalli RK, Gaasch JA, Bohn KA, Thorsheim HR, Liewehr DJ, Davis S, Reilly JF, Walker R, Bronder JL, Feigenbaum L, Steinberg SM, Camphausen K, Meltzer PS, Richon VM, Smith QR, Steeg PS.

Clin Cancer Res. 2009 Oct 1;15(19):6148-57. doi: 10.1158/1078-0432.CCR-09-1039. Epub 2009 Sep 29.

13.

Notch1 upregulates LPS-induced macrophage activation by increasing NF-kappaB activity.

Monsalve E, Ruiz-García A, Baladrón V, Ruiz-Hidalgo MJ, Sánchez-Solana B, Rivero S, García-Ramírez JJ, Rubio A, Laborda J, Díaz-Guerra MJ.

Eur J Immunol. 2009 Sep;39(9):2556-70. doi: 10.1002/eji.200838722.

14.

Genes that mediate breast cancer metastasis to the brain.

Bos PD, Zhang XH, Nadal C, Shu W, Gomis RR, Nguyen DX, Minn AJ, van de Vijver MJ, Gerald WL, Foekens JA, Massagué J.

Nature. 2009 Jun 18;459(7249):1005-9. doi: 10.1038/nature08021. Epub 2009 May 6.

15.

Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature.

Charafe-Jauffret E, Ginestier C, Iovino F, Wicinski J, Cervera N, Finetti P, Hur MH, Diebel ME, Monville F, Dutcher J, Brown M, Viens P, Xerri L, Bertucci F, Stassi G, Dontu G, Birnbaum D, Wicha MS.

Cancer Res. 2009 Feb 15;69(4):1302-13. doi: 10.1158/0008-5472.CAN-08-2741. Epub 2009 Feb 3.

16.

Notch signalling in cancer stem cells.

Bolós V, Blanco M, Medina V, Aparicio G, Díaz-Prado S, Grande E.

Clin Transl Oncol. 2009 Jan;11(1):11-9. Review.

PMID:
19155199
17.

Targeted knockdown of Notch1 inhibits invasion of human prostate cancer cells concomitant with inhibition of matrix metalloproteinase-9 and urokinase plasminogen activator.

Bin Hafeez B, Adhami VM, Asim M, Siddiqui IA, Bhat KM, Zhong W, Saleem M, Din M, Setaluri V, Mukhtar H.

Clin Cancer Res. 2009 Jan 15;15(2):452-9. doi: 10.1158/1078-0432.CCR-08-1631.

18.

Blockade of Notch signaling in tumor-bearing mice may lead to tumor regression, progression, or metastasis, depending on tumor cell types.

Hu XB, Feng F, Wang YC, Wang L, He F, Dou GR, Liang L, Zhang HW, Liang YM, Han H.

Neoplasia. 2009 Jan;11(1):32-8.

19.

A functional Notch-survivin gene signature in basal breast cancer.

Lee CW, Simin K, Liu Q, Plescia J, Guha M, Khan A, Hsieh CC, Altieri DC.

Breast Cancer Res. 2008;10(6):R97. doi: 10.1186/bcr2200. Epub 2008 Nov 24.

20.

Notch signaling regulates mammary stem cell function and luminal cell-fate commitment.

Bouras T, Pal B, Vaillant F, Harburg G, Asselin-Labat ML, Oakes SR, Lindeman GJ, Visvader JE.

Cell Stem Cell. 2008 Oct 9;3(4):429-41. doi: 10.1016/j.stem.2008.08.001.

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