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Items: 1 to 20 of 44

1.

Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair.

Simsek D, Furda A, Gao Y, Artus J, Brunet E, Hadjantonakis AK, Van Houten B, Shuman S, McKinnon PJ, Jasin M.

Nature. 2011 Mar 10;471(7337):245-8. doi: 10.1038/nature09794.

2.

DNA ligase III is critical for mtDNA integrity but not Xrcc1-mediated nuclear DNA repair.

Gao Y, Katyal S, Lee Y, Zhao J, Rehg JE, Russell HR, McKinnon PJ.

Nature. 2011 Mar 10;471(7337):240-4. doi: 10.1038/nature09773.

3.

CtIP promotes microhomology-mediated alternative end joining during class-switch recombination.

Lee-Theilen M, Matthews AJ, Kelly D, Zheng S, Chaudhuri J.

Nat Struct Mol Biol. 2011 Jan;18(1):75-9. doi: 10.1038/nsmb.1942. Epub 2010 Dec 5.

4.

An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway.

Zhang Y, Jasin M.

Nat Struct Mol Biol. 2011 Jan;18(1):80-4. doi: 10.1038/nsmb.1940. Epub 2010 Dec 5.

5.

Triggers for genomic rearrangements: insights into genomic, cellular and environmental influences.

Mani RS, Chinnaiyan AM.

Nat Rev Genet. 2010 Dec;11(12):819-29. doi: 10.1038/nrg2883. Epub 2010 Nov 3. Review. Erratum in: Nat Rev Genet. 2011 Feb;12(2):150.

PMID:
21045868
6.

Genome editing with engineered zinc finger nucleases.

Urnov FD, Rebar EJ, Holmes MC, Zhang HS, Gregory PD.

Nat Rev Genet. 2010 Sep;11(9):636-46. doi: 10.1038/nrg2842. Review.

PMID:
20717154
7.

SnapShot: Nonhomologous DNA end joining (NHEJ).

Lieber MR, Wilson TE.

Cell. 2010 Aug 6;142(3):496-496.e1. doi: 10.1016/j.cell.2010.07.035. No abstract available.

8.

Distinct factors control histone variant H3.3 localization at specific genomic regions.

Goldberg AD, Banaszynski LA, Noh KM, Lewis PW, Elsaesser SJ, Stadler S, Dewell S, Law M, Guo X, Li X, Wen D, Chapgier A, DeKelver RC, Miller JC, Lee YL, Boydston EA, Holmes MC, Gregory PD, Greally JM, Rafii S, Yang C, Scambler PJ, Garrick D, Gibbons RJ, Higgs DR, Cristea IM, Urnov FD, Zheng D, Allis CD.

Cell. 2010 Mar 5;140(5):678-91. doi: 10.1016/j.cell.2010.01.003.

9.

Alternative end-joining is suppressed by the canonical NHEJ component Xrcc4-ligase IV during chromosomal translocation formation.

Simsek D, Jasin M.

Nat Struct Mol Biol. 2010 Apr;17(4):410-6. doi: 10.1038/nsmb.1773. Epub 2010 Mar 7.

10.

Ku regulates the non-homologous end joining pathway choice of DNA double-strand break repair in human somatic cells.

Fattah F, Lee EH, Weisensel N, Wang Y, Lichter N, Hendrickson EA.

PLoS Genet. 2010 Feb 26;6(2):e1000855. doi: 10.1371/journal.pgen.1000855.

11.

The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway.

Lieber MR.

Annu Rev Biochem. 2010;79:181-211. doi: 10.1146/annurev.biochem.052308.093131. Review.

12.

Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70.

Boboila C, Jankovic M, Yan CT, Wang JH, Wesemann DR, Zhang T, Fazeli A, Feldman L, Nussenzweig A, Nussenzweig M, Alt FW.

Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3034-9. doi: 10.1073/pnas.0915067107. Epub 2010 Jan 25. Erratum in: Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5731.

13.

Complex landscapes of somatic rearrangement in human breast cancer genomes.

Stephens PJ, McBride DJ, Lin ML, Varela I, Pleasance ED, Simpson JT, Stebbings LA, Leroy C, Edkins S, Mudie LJ, Greenman CD, Jia M, Latimer C, Teague JW, Lau KW, Burton J, Quail MA, Swerdlow H, Churcher C, Natrajan R, Sieuwerts AM, Martens JW, Silver DP, Langerød A, Russnes HE, Foekens JA, Reis-Filho JS, van 't Veer L, Richardson AL, Børresen-Dale AL, Campbell PJ, Futreal PA, Stratton MR.

Nature. 2009 Dec 24;462(7276):1005-10. doi: 10.1038/nature08645.

14.

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases.

Hockemeyer D, Soldner F, Beard C, Gao Q, Mitalipova M, DeKelver RC, Katibah GE, Amora R, Boydston EA, Zeitler B, Meng X, Miller JC, Zhang L, Rebar EJ, Gregory PD, Urnov FD, Jaenisch R.

Nat Biotechnol. 2009 Sep;27(9):851-7. doi: 10.1038/nbt.1562. Epub 2009 Aug 13.

15.

Multiple functions of MRN in end-joining pathways during isotype class switching.

Dinkelmann M, Spehalski E, Stoneham T, Buis J, Wu Y, Sekiguchi JM, Ferguson DO.

Nat Struct Mol Biol. 2009 Aug;16(8):808-13. doi: 10.1038/nsmb.1639. Epub 2009 Jul 26.

16.

Role of mammalian Mre11 in classical and alternative nonhomologous end joining.

Xie A, Kwok A, Scully R.

Nat Struct Mol Biol. 2009 Aug;16(8):814-8. doi: 10.1038/nsmb.1640. Epub 2009 Jul 26.

17.

Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells.

Rass E, Grabarz A, Plo I, Gautier J, Bertrand P, Lopez BS.

Nat Struct Mol Biol. 2009 Aug;16(8):819-24. doi: 10.1038/nsmb.1641. Epub 2009 Jul 26.

PMID:
19633668
18.

Chromosomal translocations induced at specified loci in human stem cells.

Brunet E, Simsek D, Tomishima M, DeKelver R, Choi VM, Gregory P, Urnov F, Weinstock DM, Jasin M.

Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10620-5. doi: 10.1073/pnas.0902076106. Epub 2009 Jun 23.

19.

Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair.

Bennardo N, Cheng A, Huang N, Stark JM.

PLoS Genet. 2008 Jun 27;4(6):e1000110. doi: 10.1371/journal.pgen.1000110.

20.

Eukaryotic DNA ligases: structural and functional insights.

Ellenberger T, Tomkinson AE.

Annu Rev Biochem. 2008;77:313-38. doi: 10.1146/annurev.biochem.77.061306.123941. Review.

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