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Expression of αvβ8 integrin on dendritic cells regulates Th17 cell development and experimental autoimmune encephalomyelitis in mice.

Melton AC, Bailey-Bucktrout SL, Travis MA, Fife BT, Bluestone JA, Sheppard D.

J Clin Invest. 2010 Dec;120(12):4436-44. doi: 10.1172/JCI43786. Epub 2010 Nov 22.


αv Integrin expression by DCs is required for Th17 cell differentiation and development of experimental autoimmune encephalomyelitis in mice.

Acharya M, Mukhopadhyay S, Païdassi H, Jamil T, Chow C, Kissler S, Stuart LM, Hynes RO, Lacy-Hulbert A.

J Clin Invest. 2010 Dec;120(12):4445-52. doi: 10.1172/JCI43796. Epub 2010 Nov 22.


Expression of the T helper 17-associated cytokines IL-17A and IL-17F in asthma and COPD.

Doe C, Bafadhel M, Siddiqui S, Desai D, Mistry V, Rugman P, McCormick M, Woods J, May R, Sleeman MA, Anderson IK, Brightling CE.

Chest. 2010 Nov;138(5):1140-7. doi: 10.1378/chest.09-3058. Epub 2010 Jun 10.


Human fibroblasts support the expansion of IL-17-producing T cells via up-regulation of IL-23 production by dendritic cells.

Schirmer C, Klein C, von Bergen M, Simon JC, Saalbach A.

Blood. 2010 Sep 9;116(10):1715-25. doi: 10.1182/blood-2010-01-263509. Epub 2010 Jun 10.


Myeloid and plasmacytoid dendritic cells in induced sputum after allergen inhalation in subjects with asthma.

Dua B, Watson RM, Gauvreau GM, O'Byrne PM.

J Allergy Clin Immunol. 2010 Jul;126(1):133-9. doi: 10.1016/j.jaci.2010.04.006. Epub 2010 Jun 9.


Tracheal Basal cells: a facultative progenitor cell pool.

Cole BB, Smith RW, Jenkins KM, Graham BB, Reynolds PR, Reynolds SD.

Am J Pathol. 2010 Jul;177(1):362-76. doi: 10.2353/ajpath.2010.090870. Epub 2010 Jun 3. Erratum in: Am J Pathol. 2010 Oct;177(4):2145.


In vivo disruption of TGF-beta signaling by Smad7 in airway epithelium alleviates allergic asthma but aggravates lung carcinogenesis in mouse.

Luo X, Ding Q, Wang M, Li Z, Mao K, Sun B, Pan Y, Wang Z, Zang YQ, Chen Y.

PLoS One. 2010 Apr 13;5(4):e10149. doi: 10.1371/journal.pone.0010149.


Lung myeloid dendritic cells coordinately induce TH1 and TH17 responses in human emphysema.

Shan M, Cheng HF, Song LZ, Roberts L, Green L, Hacken-Bitar J, Huh J, Bakaeen F, Coxson HO, Storness-Bliss C, Ramchandani M, Lee SH, Corry DB, Kheradmand F.

Sci Transl Med. 2009 Oct 28;1(4):4ra10. doi: 10.1126/scitranlsmed.3000154.


The inflammasomes.

Schroder K, Tschopp J.

Cell. 2010 Mar 19;140(6):821-32. doi: 10.1016/j.cell.2010.01.040. Review.


Bleomycin and IL-1beta-mediated pulmonary fibrosis is IL-17A dependent.

Wilson MS, Madala SK, Ramalingam TR, Gochuico BR, Rosas IO, Cheever AW, Wynn TA.

J Exp Med. 2010 Mar 15;207(3):535-52. doi: 10.1084/jem.20092121. Epub 2010 Feb 22.


Temporal changes in dendritic cell subsets, cross-priming and costimulation via CD70 control CD8(+) T cell responses to influenza.

Ballesteros-Tato A, León B, Lund FE, Randall TD.

Nat Immunol. 2010 Mar;11(3):216-24. doi: 10.1038/ni.1838. Epub 2010 Jan 24. Erratum in: Nat Immunol. 2010 Jul;11(7):644.


Fibrogenic reactions in lung disease.

Araya J, Nishimura SL.

Annu Rev Pathol. 2010;5:77-98. doi: 10.1146/annurev.pathol.4.110807.092217. Review.


IL-1R1/MyD88 signaling is critical for elastase-induced lung inflammation and emphysema.

Couillin I, Vasseur V, Charron S, Gasse P, Tavernier M, Guillet J, Lagente V, Fick L, Jacobs M, Coelho FR, Moser R, Ryffel B.

J Immunol. 2009 Dec 15;183(12):8195-202. doi: 10.4049/jimmunol.0803154.


The disruption of the epithelial mesenchymal trophic unit in COPD.

Behzad AR, McDonough JE, Seyednejad N, Hogg JC, Walker DC.

COPD. 2009 Dec;6(6):421-31. doi: 10.3109/15412550903341471.


Biology of lung dendritic cells at the origin of asthma.

Lambrecht BN, Hammad H.

Immunity. 2009 Sep 18;31(3):412-24. doi: 10.1016/j.immuni.2009.08.008. Review.


Correlation between serum biomarkers and BODE index in patients with stable COPD.

Liu SF, Chin CH, Wang CC, Lin MC.

Respirology. 2009 Sep;14(7):999-1004. doi: 10.1111/j.1440-1843.2009.01608.x.


Integrin-mediated transforming growth factor-beta activation, a potential therapeutic target in fibrogenic disorders.

Nishimura SL.

Am J Pathol. 2009 Oct;175(4):1362-70. doi: 10.2353/ajpath.2009.090393. Epub 2009 Sep 3. Review.


Dermal fibroblasts promote the migration of dendritic cells.

Saalbach A, Klein C, Schirmer C, Briest W, Anderegg U, Simon JC.

J Invest Dermatol. 2010 Feb;130(2):444-54. doi: 10.1038/jid.2009.253. Epub 2009 Aug 27.


Allergic sensitization through the airway primes Th17-dependent neutrophilia and airway hyperresponsiveness.

Wilson RH, Whitehead GS, Nakano H, Free ME, Kolls JK, Cook DN.

Am J Respir Crit Care Med. 2009 Oct 15;180(8):720-30. doi: 10.1164/rccm.200904-0573OC. Epub 2009 Aug 6.


Isolation of dendritic cells.

Inaba K, Swiggard WJ, Steinman RM, Romani N, Schuler G, Brinster C.

Curr Protoc Immunol. 2009 Aug;Chapter 3:Unit 3.7. doi: 10.1002/0471142735.im0307s86.


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