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Items: 1 to 20 of 46


Ectopic respiratory epithelial cell differentiation in bronchiolised distal airspaces in idiopathic pulmonary fibrosis.

Plantier L, Crestani B, Wert SE, Dehoux M, Zweytick B, Guenther A, Whitsett JA.

Thorax. 2011 Aug;66(8):651-7. doi: 10.1136/thx.2010.151555. Epub 2011 Mar 21.


Generation of anterior foregut endoderm from human embryonic and induced pluripotent stem cells.

Green MD, Chen A, Nostro MC, d'Souza SL, Schaniel C, Lemischka IR, Gouon-Evans V, Keller G, Snoeck HW.

Nat Biotechnol. 2011 Mar;29(3):267-72. doi: 10.1038/nbt.1788. Epub 2011 Feb 27.


Abnormalities of the TITF-1 lineage-specific oncogene in NSCLC: implications in lung cancer pathogenesis and prognosis.

Tang X, Kadara H, Behrens C, Liu DD, Xiao Y, Rice D, Gazdar AF, Fujimoto J, Moran C, Varella-Garcia M, Lee JJ, Hong WK, Wistuba II.

Clin Cancer Res. 2011 Apr 15;17(8):2434-43. doi: 10.1158/1078-0432.CCR-10-1412. Epub 2011 Jan 21.


Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro.

Spence JR, Mayhew CN, Rankin SA, Kuhar MF, Vallance JE, Tolle K, Hoskins EE, Kalinichenko VV, Wells SI, Zorn AM, Shroyer NF, Wells JM.

Nature. 2011 Feb 3;470(7332):105-9. doi: 10.1038/nature09691. Epub 2010 Dec 12.


Both gene amplification and allelic loss occur at 14q13.3 in lung cancer.

Harris T, Pan Q, Sironi J, Lutz D, Tian J, Sapkar J, Perez-Soler R, Keller S, Locker J.

Clin Cancer Res. 2011 Feb 15;17(4):690-9. doi: 10.1158/1078-0432.CCR-10-1892. Epub 2010 Dec 10.


Sox2 activates cell proliferation and differentiation in the respiratory epithelium.

Tompkins DH, Besnard V, Lange AW, Keiser AR, Wert SE, Bruno MD, Whitsett JA.

Am J Respir Cell Mol Biol. 2011 Jul;45(1):101-10. doi: 10.1165/rcmb.2010-0149OC. Epub 2010 Sep 20.


Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling.

Rock JR, Randell SH, Hogan BL.

Dis Model Mech. 2010 Sep-Oct;3(9-10):545-56. doi: 10.1242/dmm.006031. Epub 2010 Aug 10. Review.


Lung organogenesis.

Warburton D, El-Hashash A, Carraro G, Tiozzo C, Sala F, Rogers O, De Langhe S, Kemp PJ, Riccardi D, Torday J, Bellusci S, Shi W, Lubkin SR, Jesudason E.

Curr Top Dev Biol. 2010;90:73-158. doi: 10.1016/S0070-2153(10)90003-3. Review.


Evidence that SOX2 overexpression is oncogenic in the lung.

Lu Y, Futtner C, Rock JR, Xu X, Whitworth W, Hogan BL, Onaitis MW.

PLoS One. 2010 Jun 10;5(6):e11022. doi: 10.1371/journal.pone.0011022.


Foxa2 programs Th2 cell-mediated innate immunity in the developing lung.

Chen G, Wan H, Luo F, Zhang L, Xu Y, Lewkowich I, Wills-Karp M, Whitsett JA.

J Immunol. 2010 Jun 1;184(11):6133-41. doi: 10.4049/jimmunol.1000223. Epub 2010 May 5.


Pulmonary pathology in thyroid transcription factor-1 deficiency syndrome.

Galambos C, Levy H, Cannon CL, Vargas SO, Reid LM, Cleveland R, Lindeman R, deMello DE, Wert SE, Whitsett JA, Perez-Atayde AR, Kozakewich H.

Am J Respir Crit Care Med. 2010 Aug 15;182(4):549-54. doi: 10.1164/rccm.201002-0167CR. Epub 2010 Mar 4.


Preparing for the first breath: genetic and cellular mechanisms in lung development.

Morrisey EE, Hogan BL.

Dev Cell. 2010 Jan 19;18(1):8-23. doi: 10.1016/j.devcel.2009.12.010. Review.


Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate.

Morimoto M, Liu Z, Cheng HT, Winters N, Bader D, Kopan R.

J Cell Sci. 2010 Jan 15;123(Pt 2):213-24. doi: 10.1242/jcs.058669.


Sox2 is required for maintenance and differentiation of bronchiolar Clara, ciliated, and goblet cells.

Tompkins DH, Besnard V, Lange AW, Wert SE, Keiser AR, Smith AN, Lang R, Whitsett JA.

PLoS One. 2009 Dec 14;4(12):e8248. doi: 10.1371/journal.pone.0008248.


Mechanisms of lung development: contribution to adult lung disease and relevance to chronic obstructive pulmonary disease.

Shi W, Chen F, Cardoso WV.

Proc Am Thorac Soc. 2009 Dec 1;6(7):558-63. doi: 10.1513/pats.200905-031RM. Review.


Centrioles, centrosomes, and cilia in health and disease.

Nigg EA, Raff JW.

Cell. 2009 Nov 13;139(4):663-78. doi: 10.1016/j.cell.2009.10.036. Review.


SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas.

Bass AJ, Watanabe H, Mermel CH, Yu S, Perner S, Verhaak RG, Kim SY, Wardwell L, Tamayo P, Gat-Viks I, Ramos AH, Woo MS, Weir BA, Getz G, Beroukhim R, O'Kelly M, Dutt A, Rozenblatt-Rosen O, Dziunycz P, Komisarof J, Chirieac LR, Lafargue CJ, Scheble V, Wilbertz T, Ma C, Rao S, Nakagawa H, Stairs DB, Lin L, Giordano TJ, Wagner P, Minna JD, Gazdar AF, Zhu CQ, Brose MS, Cecconello I, Ribeiro U Jr, Marie SK, Dahl O, Shivdasani RA, Tsao MS, Rubin MA, Wong KK, Regev A, Hahn WC, Beer DG, Rustgi AK, Meyerson M.

Nat Genet. 2009 Nov;41(11):1238-42. doi: 10.1038/ng.465. Epub 2009 Oct 4.


SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production.

Chen G, Korfhagen TR, Xu Y, Kitzmiller J, Wert SE, Maeda Y, Gregorieff A, Clevers H, Whitsett JA.

J Clin Invest. 2009 Oct;119(10):2914-24. doi: 10.1172/JCI39731. Epub 2009 Sep 14.


Distinct roles of FOXA2 and FOXA3 in allergic airway disease and asthma.

Park SW, Verhaeghe C, Nguyenvu LT, Barbeau R, Eisley CJ, Nakagami Y, Huang X, Woodruff PG, Fahy JV, Erle DJ.

Am J Respir Crit Care Med. 2009 Oct 1;180(7):603-10. doi: 10.1164/rccm.200811-1768OC. Epub 2009 Jul 23.


Vertebrate endoderm development and organ formation.

Zorn AM, Wells JM.

Annu Rev Cell Dev Biol. 2009;25:221-51. doi: 10.1146/annurev.cellbio.042308.113344. Review.

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