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Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue.

Kosteli A, Sugaru E, Haemmerle G, Martin JF, Lei J, Zechner R, Ferrante AW Jr.

J Clin Invest. 2010 Oct;120(10):3466-79. doi: 10.1172/JCI42845. Epub 2010 Sep 27.


Adipose tissue endothelial cells from obese human subjects: differences among depots in angiogenic, metabolic, and inflammatory gene expression and cellular senescence.

Villaret A, Galitzky J, Decaunes P, Estève D, Marques MA, Sengenès C, Chiotasso P, Tchkonia T, Lafontan M, Kirkland JL, Bouloumié A.

Diabetes. 2010 Nov;59(11):2755-63. doi: 10.2337/db10-0398. Epub 2010 Aug 16.


Gluttony, sloth and the metabolic syndrome: a roadmap to lipotoxicity.

Unger RH, Scherer PE.

Trends Endocrinol Metab. 2010 Jun;21(6):345-52. doi: 10.1016/j.tem.2010.01.009. Epub 2010 Mar 10. Review.


Adipose tissue angiogenesis as a therapeutic target for obesity and metabolic diseases.

Cao Y.

Nat Rev Drug Discov. 2010 Feb;9(2):107-15. doi: 10.1038/nrd3055. Review.


Lipolysis in adipocytes.

Ahmadian M, Wang Y, Sul HS.

Int J Biochem Cell Biol. 2010 May;42(5):555-9. doi: 10.1016/j.biocel.2009.12.009. Epub 2009 Dec 16. Review.


Lipid homeostasis, lipotoxicity and the metabolic syndrome.

Unger RH, Clark GO, Scherer PE, Orci L.

Biochim Biophys Acta. 2010 Mar;1801(3):209-14. doi: 10.1016/j.bbalip.2009.10.006. Epub 2009 Nov 27. Review.


Mechanisms of obesity and related pathologies: the macro- and microcirculation of adipose tissue.

Rutkowski JM, Davis KE, Scherer PE.

FEBS J. 2009 Oct;276(20):5738-46. doi: 10.1111/j.1742-4658.2009.07303.x. Epub 2009 Sep 15. Review.


Fatty acid flux in adipocytes: the in's and out's of fat cell lipid trafficking.

Thompson BR, Lobo S, Bernlohr DA.

Mol Cell Endocrinol. 2010 Apr 29;318(1-2):24-33. doi: 10.1016/j.mce.2009.08.015. Epub 2009 Aug 29. Review.


CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity.

Nishimura S, Manabe I, Nagasaki M, Eto K, Yamashita H, Ohsugi M, Otsu M, Hara K, Ueki K, Sugiura S, Yoshimura K, Kadowaki T, Nagai R.

Nat Med. 2009 Aug;15(8):914-20. doi: 10.1038/nm.1964. Epub 2009 Jul 26.


Normalization of obesity-associated insulin resistance through immunotherapy.

Winer S, Chan Y, Paltser G, Truong D, Tsui H, Bahrami J, Dorfman R, Wang Y, Zielenski J, Mastronardi F, Maezawa Y, Drucker DJ, Engleman E, Winer D, Dosch HM.

Nat Med. 2009 Aug;15(8):921-9. doi: 10.1038/nm.2001. Epub 2009 Jul 26.


Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice.

Liu J, Divoux A, Sun J, Zhang J, Clément K, Glickman JN, Sukhova GK, Wolters PJ, Du J, Gorgun CZ, Doria A, Libby P, Blumberg RS, Kahn BB, Hotamisligil GS, Shi GP.

Nat Med. 2009 Aug;15(8):940-5. doi: 10.1038/nm.1994. Epub 2009 Jul 26.


Microarray analysis identifies matrix metalloproteinases (MMPs) as key genes whose expression is up-regulated in human adipocytes by macrophage-conditioned medium.

O'Hara A, Lim FL, Mazzatti DJ, Trayhurn P.

Pflugers Arch. 2009 Oct;458(6):1103-14. doi: 10.1007/s00424-009-0693-8. Epub 2009 Jul 9.


Hypoxia-inducible factor 1alpha induces fibrosis and insulin resistance in white adipose tissue.

Halberg N, Khan T, Trujillo ME, Wernstedt-Asterholm I, Attie AD, Sherwani S, Wang ZV, Landskroner-Eiger S, Dineen S, Magalang UJ, Brekken RA, Scherer PE.

Mol Cell Biol. 2009 Aug;29(16):4467-83. doi: 10.1128/MCB.00192-09. Epub 2009 Jun 22.


Angiogenesis, adipokines and breast cancer.

Vona-Davis L, Rose DP.

Cytokine Growth Factor Rev. 2009 Jun;20(3):193-201. doi: 10.1016/j.cytogfr.2009.05.007. Epub 2009 Jun 10. Review.


Proangiogenic contribution of adiponectin toward mammary tumor growth in vivo.

Landskroner-Eiger S, Qian B, Muise ES, Nawrocki AR, Berger JP, Fine EJ, Koba W, Deng Y, Pollard JW, Scherer PE.

Clin Cancer Res. 2009 May 15;15(10):3265-76. doi: 10.1158/1078-0432.CCR-08-2649. Epub 2009 May 15.


Blockade of VEGFR2 and not VEGFR1 can limit diet-induced fat tissue expansion: role of local versus bone marrow-derived endothelial cells.

Tam J, Duda DG, Perentes JY, Quadri RS, Fukumura D, Jain RK.

PLoS One. 2009;4(3):e4974. doi: 10.1371/journal.pone.0004974. Epub 2009 Mar 31.


Metabolic dysregulation and adipose tissue fibrosis: role of collagen VI.

Khan T, Muise ES, Iyengar P, Wang ZV, Chandalia M, Abate N, Zhang BB, Bonaldo P, Chua S, Scherer PE.

Mol Cell Biol. 2009 Mar;29(6):1575-91. doi: 10.1128/MCB.01300-08. Epub 2008 Dec 29.


Role of hypoxia in obesity-induced disorders of glucose and lipid metabolism in adipose tissue.

Yin J, Gao Z, He Q, Zhou D, Guo Z, Ye J.

Am J Physiol Endocrinol Metab. 2009 Feb;296(2):E333-42. doi: 10.1152/ajpendo.90760.2008. Epub 2008 Dec 9.


Adipocyte metabolism and obesity.

Attie AD, Scherer PE.

J Lipid Res. 2009 Apr;50 Suppl:S395-9. doi: 10.1194/jlr.R800057-JLR200. Epub 2008 Nov 17. Review.


Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals.

Patsouris D, Li PP, Thapar D, Chapman J, Olefsky JM, Neels JG.

Cell Metab. 2008 Oct;8(4):301-9. doi: 10.1016/j.cmet.2008.08.015.

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