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Items: 1 to 20 of 49


Hypertrophic differentiation and calcification during intervertebral disc degeneration.

Rutges JP, Duit RA, Kummer JA, Oner FC, van Rijen MH, Verbout AJ, Castelein RM, Dhert WJ, Creemers LB.

Osteoarthritis Cartilage. 2010 Nov;18(11):1487-95. doi: 10.1016/j.joca.2010.08.006.


Characterization of the human nucleus pulposus cell phenotype and evaluation of novel marker gene expression to define adult stem cell differentiation.

Minogue BM, Richardson SM, Zeef LA, Freemont AJ, Hoyland JA.

Arthritis Rheum. 2010 Dec;62(12):3695-705. doi: 10.1002/art.27710.


Notochordal cell conditioned medium stimulates mesenchymal stem cell differentiation toward a young nucleus pulposus phenotype.

Korecki CL, Taboas JM, Tuan RS, Iatridis JC.

Stem Cell Res Ther. 2010 Jun 16;1(2):18. doi: 10.1186/scrt18.


Disc regeneration therapy using marrow mesenchymal cell transplantation: a report of two case studies.

Yoshikawa T, Ueda Y, Miyazaki K, Koizumi M, Takakura Y.

Spine (Phila Pa 1976). 2010 May 15;35(11):E475-80. doi: 10.1097/BRS.0b013e3181cd2cf4.


Transcriptional profiling of bovine intervertebral disc cells: implications for identification of normal and degenerate human intervertebral disc cell phenotypes.

Minogue BM, Richardson SM, Zeef LA, Freemont AJ, Hoyland JA.

Arthritis Res Ther. 2010;12(1):R22. doi: 10.1186/ar2929.


Impact of growth factors and PTHrP on early and late chondrogenic differentiation of human mesenchymal stem cells.

Weiss S, Hennig T, Bock R, Steck E, Richter W.

J Cell Physiol. 2010 Apr;223(1):84-93. doi: 10.1002/jcp.22013.


Human nucleus pulposus cells significantly enhanced biological properties in a coculture system with direct cell-to-cell contact with autologous mesenchymal stem cells.

Watanabe T, Sakai D, Yamamoto Y, Iwashina T, Serigano K, Tamura F, Mochida J.

J Orthop Res. 2010 May;28(5):623-30. doi: 10.1002/jor.21036.


Variations in gene and protein expression in human nucleus pulposus in comparison with annulus fibrosus and cartilage cells: potential associations with aging and degeneration.

Rutges J, Creemers LB, Dhert W, Milz S, Sakai D, Mochida J, Alini M, Grad S.

Osteoarthritis Cartilage. 2010 Mar;18(3):416-23. doi: 10.1016/j.joca.2009.09.009.


Mesenchymal stem cells in regenerative medicine: opportunities and challenges for articular cartilage and intervertebral disc tissue engineering.

Richardson SM, Hoyland JA, Mobasheri R, Csaki C, Shakibaei M, Mobasheri A.

J Cell Physiol. 2010 Jan;222(1):23-32. doi: 10.1002/jcp.21915. Review.


Notochordal intervertebral disc cells: sensitivity to nutrient deprivation.

Guehring T, Wilde G, Sumner M, Grünhagen T, Karney GB, Tirlapur UK, Urban JP.

Arthritis Rheum. 2009 Apr;60(4):1026-34. doi: 10.1002/art.24407.


Matrix metalloprotease inhibitors suppress initiation and progression of chondrogenic differentiation of mesenchymal stromal cells in vitro.

Bertram H, Boeuf S, Wachters J, Boehmer S, Heisel C, Hofmann MW, Piecha D, Richter W.

Stem Cells Dev. 2009 Jul-Aug;18(6):881-92. doi: 10.1089/scd.2008.0306.


An in vitro study investigating the survival and phenotype of mesenchymal stem cells following injection into nucleus pulposus tissue.

Le Maitre CL, Baird P, Freemont AJ, Hoyland JA.

Arthritis Res Ther. 2009;11(1):R20. doi: 10.1186/ar2611.


MSC response to pH levels found in degenerating intervertebral discs.

Wuertz K, Godburn K, Iatridis JC.

Biochem Biophys Res Commun. 2009 Feb 20;379(4):824-9. doi: 10.1016/j.bbrc.2008.12.145.


Future perspectives of cell-based therapy for intervertebral disc disease.

Sakai D.

Eur Spine J. 2008 Dec;17 Suppl 4:452-8. doi: 10.1007/s00586-008-0743-5. Review.


Expression and regulation of neurotrophins in the nondegenerate and degenerate human intervertebral disc.

Purmessur D, Freemont AJ, Hoyland JA.

Arthritis Res Ther. 2008;10(4):R99. doi: 10.1186/ar2487.


In vitro study on interaction between human nucleus pulposus cells and mesenchymal stem cells through paracrine stimulation.

Yang SH, Wu CC, Shih TT, Sun YH, Lin FH.

Spine (Phila Pa 1976). 2008 Aug 15;33(18):1951-7. doi: 10.1097/BRS.0b013e31817e6974.


Behavior of mesenchymal stem cells in the chemical microenvironment of the intervertebral disc.

Wuertz K, Godburn K, Neidlinger-Wilke C, Urban J, Iatridis JC.

Spine (Phila Pa 1976). 2008 Aug 1;33(17):1843-9. doi: 10.1097/BRS.0b013e31817b8f53.


Feasibility of a stem cell therapy for intervertebral disc degeneration.

Sobajima S, Vadala G, Shimer A, Kim JS, Gilbertson LG, Kang JD.

Spine J. 2008 Nov-Dec;8(6):888-96.


A phenotypic comparison of intervertebral disc and articular cartilage cells in the rat.

Lee CR, Sakai D, Nakai T, Toyama K, Mochida J, Alini M, Grad S.

Eur Spine J. 2007 Dec;16(12):2174-85.

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