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Items: 1 to 20 of 138


Manganese porphyrin, MnTE-2-PyP5+, Acts as a pro-oxidant to potentiate glucocorticoid-induced apoptosis in lymphoma cells.

Jaramillo MC, Briehl MM, Crapo JD, Batinic-Haberle I, Tome ME.

Free Radic Biol Med. 2012 Apr 15;52(8):1272-84. doi: 10.1016/j.freeradbiomed.2012.02.001. Epub 2012 Feb 11.


Neuroprotective efficacy from a lipophilic redox-modulating Mn(III) N-Hexylpyridylporphyrin, MnTnHex-2-PyP: rodent models of ischemic stroke and subarachnoid hemorrhage.

Sheng H, Spasojevic I, Tse HM, Jung JY, Hong J, Zhang Z, Piganelli JD, Batinic-Haberle I, Warner DS.

J Pharmacol Exp Ther. 2011 Sep;338(3):906-16. doi: 10.1124/jpet.110.176701. Epub 2011 Jun 7.


Mn(III) meso-tetrakis-(N-ethylpyridinium-2-yl) porphyrin mitigates total body irradiation-induced long-term bone marrow suppression.

Li H, Wang Y, Pazhanisamy SK, Shao L, Batinic-Haberle I, Meng A, Zhou D.

Free Radic Biol Med. 2011 Jul 1;51(1):30-7. doi: 10.1016/j.freeradbiomed.2011.04.016. Epub 2011 Apr 14.


Cellular uptake and organ accumulation of amphipolar metallocorroles with cytoprotective and cytotoxic properties.

Okun Z, Kuperschmidt L, Youdim MB, Gross Z.

Anticancer Agents Med Chem. 2011 May 1;11(4):380-4.


Superoxide dismutase in redox biology: the roles of superoxide and hydrogen peroxide.

Buettner GR.

Anticancer Agents Med Chem. 2011 May 1;11(4):341-6. Review.


Manganese superoxide dismutase (Sod2) and redox-control of signaling events that drive metastasis.

Hempel N, Carrico PM, Melendez JA.

Anticancer Agents Med Chem. 2011 Feb;11(2):191-201. Review.


NADPH oxidase inhibition attenuates total body irradiation-induced haematopoietic genomic instability.

Pazhanisamy SK, Li H, Wang Y, Batinic-Haberle I, Zhou D.

Mutagenesis. 2011 May;26(3):431-5. doi: 10.1093/mutage/ger001. Epub 2011 Mar 17.


Redox-active quinones and ascorbate: an innovative cancer therapy that exploits the vulnerability of cancer cells to oxidative stress.

Verrax J, Beck R, Dejeans N, Glorieux C, Sid B, Pedrosa RC, Benites J, Vásquez D, Valderrama JA, Calderon PB.

Anticancer Agents Med Chem. 2011 Feb;11(2):213-21. Review.


Methoxy-derivatization of alkyl chains increases the in vivo efficacy of cationic Mn porphyrins. Synthesis, characterization, SOD-like activity, and SOD-deficient E. coli study of meta Mn(III) N-methoxyalkylpyridylporphyrins.

Tovmasyan AG, Rajic Z, Spasojevic I, Reboucas JS, Chen X, Salvemini D, Sheng H, Warner DS, Benov L, Batinic-Haberle I.

Dalton Trans. 2011 Apr 28;40(16):4111-21. doi: 10.1039/c0dt01321h. Epub 2011 Mar 8.


The potential of Zn(II) N-alkylpyridylporphyrins for anticancer therapy.

Benov L, Craik J, Batinic-Haberle I.

Anticancer Agents Med Chem. 2011 Feb;11(2):233-41.


Mitochondrial superoxide dismutase--signals of distinction.

Miriyala S, Holley AK, St Clair DK.

Anticancer Agents Med Chem. 2011 Feb;11(2):181-90. Review.


Texaphyrins: tumor localizing redox active expanded porphyrins.

Arambula JF, Preihs C, Borthwick D, Magda D, Sessler JL.

Anticancer Agents Med Chem. 2011 Feb;11(2):222-32. Review.


Cellular redox modulator, ortho Mn(III) meso-tetrakis(N-n-hexylpyridinium-2-yl)porphyrin, MnTnHex-2-PyP(5+) in the treatment of brain tumors.

Keir ST, Dewhirst MW, Kirkpatrick JP, Bigner DD, Batinic-Haberle I.

Anticancer Agents Med Chem. 2011 Feb;11(2):202-12.


Does more MnSOD mean more hydrogen peroxide?

MacMillan-Crow LA, Crow JP.

Anticancer Agents Med Chem. 2011 Feb;11(2):178-80. Review.


Anticancer activity of metal complexes: involvement of redox processes.

Jungwirth U, Kowol CR, Keppler BK, Hartinger CG, Berger W, Heffeter P.

Antioxid Redox Signal. 2011 Aug 15;15(4):1085-127. doi: 10.1089/ars.2010.3663. Epub 2011 May 11. Review.


Superoxide dismutases: anti- versus pro- oxidants?

Fridovich I.

Anticancer Agents Med Chem. 2011 Feb;11(2):175-7.


Acid-base and electrochemical properties of manganese meso(ortho- and meta-N-ethylpyridyl)porphyrins: potentiometric, spectrophotometric and spectroelectrochemical study of protolytic and redox equilibria.

Weitner T, Budimir A, Kos I, Batinić-Haberle I, Biruš M.

Dalton Trans. 2010 Dec 28;39(48):11568-76. doi: 10.1039/c0dt00585a. Epub 2010 Nov 4.


Bioavailability of metalloporphyrin-based SOD mimics is greatly influenced by a single charge residing on a Mn site.

Spasojevic I, Kos I, Benov LT, Rajic Z, Fels D, Dedeugd C, Ye X, Vujaskovic Z, Reboucas JS, Leong KW, Dewhirst MW, Batinic-Haberle I.

Free Radic Res. 2011 Feb;45(2):188-200. doi: 10.3109/10715762.2010.522575. Epub 2010 Oct 13.


Regulation of mitochondrial glutathione redox status and protein glutathionylation by respiratory substrates.

Garcia J, Han D, Sancheti H, Yap LP, Kaplowitz N, Cadenas E.

J Biol Chem. 2010 Dec 17;285(51):39646-54. doi: 10.1074/jbc.M110.164160. Epub 2010 Oct 11.

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