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Albumin activates the canonical TGF receptor-smad signaling pathway but this is not required for activation of astrocytes.

Ralay Ranaivo H, Patel F, Wainwright MS.

Exp Neurol. 2010 Dec;226(2):310-9. doi: 10.1016/j.expneurol.2010.09.005. Epub 2010 Sep 18.


Albumin activates astrocytes and microglia through mitogen-activated protein kinase pathways.

Ralay Ranaivo H, Wainwright MS.

Brain Res. 2010 Feb 8;1313:222-31. doi: 10.1016/j.brainres.2009.11.063. Epub 2009 Dec 2.


Differential effects of albumin on microglia and macrophages; implications for neurodegeneration following blood-brain barrier damage.

Hooper C, Pinteaux-Jones F, Fry VA, Sevastou IG, Baker D, Heales SJ, Pocock JM.

J Neurochem. 2009 May;109(3):694-705. doi: 10.1111/j.1471-4159.2009.05953.x. Epub 2009 Feb 2.


The role of endogenously produced extracellular hsp72 in mononuclear cell reprogramming.

Abboud PA, Lahni PM, Page K, Giuliano JS Jr, Harmon K, Dunsmore KE, Wong HR, Wheeler DS.

Shock. 2008 Sep;30(3):285-92. doi: 10.1097/SHK.0b013e318164e2c3.


Induction of endotoxin tolerance enhances bacterial clearance and survival in murine polymicrobial sepsis.

Wheeler DS, Lahni PM, Denenberg AG, Poynter SE, Wong HR, Cook JA, Zingarelli B.

Shock. 2008 Sep;30(3):267-73. doi: 10.1097/shk.0b013e318162c190.


Macrophage activation by endogenous danger signals.

Zhang X, Mosser DM.

J Pathol. 2008 Jan;214(2):161-78. Review.


HMGB1 preconditioning: therapeutic application for a danger signal?

Klune JR, Billiar TR, Tsung A.

J Leukoc Biol. 2008 Mar;83(3):558-63. Epub 2007 Oct 15. Review.


Saline or albumin for fluid resuscitation in patients with traumatic brain injury.

SAFE Study Investigators; Australian and New Zealand Intensive Care Society Clinical Trials Group; Australian Red Cross Blood Service; George Institute for International Health, Myburgh J, Cooper DJ, Finfer S, Bellomo R, Norton R, Bishop N, Kai Lo S, Vallance S.

N Engl J Med. 2007 Aug 30;357(9):874-84.


New developments in fluid resuscitation.

Alam HB, Rhee P.

Surg Clin North Am. 2007 Feb;87(1):55-72, vi. Review.


Can albumin administration relieve lung injury in trauma/hemorrhagic shock?

Chen ZB, Wang ZW, Ding CY, Yan JH, Gao Y, Zhang Y, Ni LM, Zhou YQ.

World J Gastroenterol. 2006 Nov 14;12(42):6884-8.


Extracellular heat shock protein-70 induces endotoxin tolerance in THP-1 cells.

Aneja R, Odoms K, Dunsmore K, Shanley TP, Wong HR.

J Immunol. 2006 Nov 15;177(10):7184-92.


Is albumin administration in the acutely ill associated with increased mortality? Results of the SOAP study.

Vincent JL, Sakr Y, Reinhart K, Sprung CL, Gerlach H, Ranieri VM; 'Sepsis Occurrence in Acutely Ill Patients' Investigators.

Crit Care. 2005;9(6):R745-54. Epub 2005 Nov 7.


Heat shock protein 10 inhibits lipopolysaccharide-induced inflammatory mediator production.

Johnson BJ, Le TT, Dobbin CA, Banovic T, Howard CB, Flores Fde M, Vanags D, Naylor DJ, Hill GR, Suhrbier A.

J Biol Chem. 2005 Feb 11;280(6):4037-47. Epub 2004 Nov 16.


Serum albumin induces iNOS expression and NO production in RAW 267.4 macrophages.

Poteser M, Wakabayashi I.

Br J Pharmacol. 2004 Sep;143(1):143-51. Epub 2004 Aug 2.


A comparison of albumin and saline for fluid resuscitation in the intensive care unit.

Finfer S, Bellomo R, Boyce N, French J, Myburgh J, Norton R; SAFE Study Investigators.

N Engl J Med. 2004 May 27;350(22):2247-56.


Molecular identification of a danger signal that alerts the immune system to dying cells.

Shi Y, Evans JE, Rock KL.

Nature. 2003 Oct 2;425(6957):516-21. Epub 2003 Sep 7.


Twenty-five percent albumin prevents lung injury following shock/resuscitation.

Powers KA, Kapus A, Khadaroo RG, He R, Marshall JC, Lindsay TF, Rotstein OD.

Crit Care Med. 2003 Sep;31(9):2355-63.


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