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IKAP/Elp1 involvement in cytoskeleton regulation and implication for familial dysautonomia.

Cheishvili D, Maayan C, Cohen-Kupiec R, Lefler S, Weil M, Ast G, Razin A.

Hum Mol Genet. 2011 Apr 15;20(8):1585-94. doi: 10.1093/hmg/ddr036.


Phosphatidylserine increases IKBKAP levels in familial dysautonomia cells.

Keren H, Donyo M, Zeevi D, Maayan C, Pupko T, Ast G.

PLoS One. 2010 Dec 29;5(12):e15884. doi: 10.1371/journal.pone.0015884.


IKAP/hELP1 down-regulation in neuroblastoma cells causes enhanced cell adhesion mediated by contactin overexpression.

Cohen-Kupiec R, Weinstein S, Kantor G, Peer D, Weil M.

Cell Adh Migr. 2010 Oct-Dec;4(4):541-50. doi: 10.4161/cam.4.4.12923.


Cell signaling by receptor tyrosine kinases.

Lemmon MA, Schlessinger J.

Cell. 2010 Jun 25;141(7):1117-34. doi: 10.1016/j.cell.2010.06.011. Review.


The Caenorhabditis elegans Elongator complex regulates neuronal alpha-tubulin acetylation.

Solinger JA, Paolinelli R, Klöss H, Scorza FB, Marchesi S, Sauder U, Mitsushima D, Capuani F, Stürzenbaum SR, Cassata G.

PLoS Genet. 2010 Jan 22;6(1):e1000820. doi: 10.1371/journal.pgen.1000820.


Elongator - an emerging role in neurological disorders.

Nguyen L, Humbert S, Saudou F, Chariot A.

Trends Mol Med. 2010 Jan;16(1):1-6. doi: 10.1016/j.molmed.2009.11.002.


Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs.

Lee G, Papapetrou EP, Kim H, Chambers SM, Tomishima MJ, Fasano CA, Ganat YM, Menon J, Shimizu F, Viale A, Tabar V, Sadelain M, Studer L.

Nature. 2009 Sep 17;461(7262):402-6. doi: 10.1038/nature08320.


The NGL family of leucine-rich repeat-containing synaptic adhesion molecules.

Woo J, Kwon SK, Kim E.

Mol Cell Neurosci. 2009 Sep;42(1):1-10. doi: 10.1016/j.mcn.2009.05.008. Review.


ToppGene Suite for gene list enrichment analysis and candidate gene prioritization.

Chen J, Bardes EE, Aronow BJ, Jegga AG.

Nucleic Acids Res. 2009 Jul;37(Web Server issue):W305-11. doi: 10.1093/nar/gkp427.


Loss-of-function of IKAP/ELP1: could neuronal migration defect underlie familial dysautonomia?

Naumanen T, Johansen LD, Coffey ET, Kallunki T.

Cell Adh Migr. 2008 Oct-Dec;2(4):236-9.


To adhere or not to adhere: the role of Cadherins in neural crest development.

Taneyhill LA.

Cell Adh Migr. 2008 Oct-Dec;2(4):223-30. Review.


Comprehensive characterization of neuroblastoma cell line subtypes reveals bilineage potential similar to neural crest stem cells.

Acosta S, Lavarino C, Paris R, Garcia I, de Torres C, Rodríguez E, Beleta H, Mora J.

BMC Dev Biol. 2009 Feb 12;9:12. doi: 10.1186/1471-213X-9-12.


Elongator controls the migration and differentiation of cortical neurons through acetylation of alpha-tubulin.

Creppe C, Malinouskaya L, Volvert ML, Gillard M, Close P, Malaise O, Laguesse S, Cornez I, Rahmouni S, Ormenese S, Belachew S, Malgrange B, Chapelle JP, Siebenlist U, Moonen G, Chariot A, Nguyen L.

Cell. 2009 Feb 6;136(3):551-64. doi: 10.1016/j.cell.2008.11.043.


Loss of mouse Ikbkap, a subunit of elongator, leads to transcriptional deficits and embryonic lethality that can be rescued by human IKBKAP.

Chen YT, Hims MM, Shetty RS, Mull J, Liu L, Leyne M, Slaugenhaupt SA.

Mol Cell Biol. 2009 Feb;29(3):736-44. doi: 10.1128/MCB.01313-08.


Disease causing mutations of calcium channels.

Lorenzon NM, Beam KG.

Channels (Austin). 2008 May-Jun;2(3):163-79. Review.


Extracellular matrix of the central nervous system: from neglect to challenge.

Zimmermann DR, Dours-Zimmermann MT.

Histochem Cell Biol. 2008 Oct;130(4):635-53. doi: 10.1007/s00418-008-0485-9. Review.


Role of platelet-derived growth factors in physiology and medicine.

Andrae J, Gallini R, Betsholtz C.

Genes Dev. 2008 May 15;22(10):1276-312. doi: 10.1101/gad.1653708. Review.


IKAP localizes to membrane ruffles with filamin A and regulates actin cytoskeleton organization and cell migration.

Johansen LD, Naumanen T, Knudsen A, Westerlund N, Gromova I, Junttila M, Nielsen C, Bøttzauw T, Tolkovsky A, Westermarck J, Coffey ET, Jäättelä M, Kallunki T.

J Cell Sci. 2008 Mar 15;121(Pt 6):854-64. doi: 10.1242/jcs.013722.


SnapShot: EGFR signaling pathway.

Yarden Y, Shilo BZ.

Cell. 2007 Nov 30;131(5):1018. No abstract available.

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