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Items: 1 to 20 of 91

1.

Cyclic AMP phosphodiesterase 4D (PDE4D) Tethers EPAC1 in a vascular endothelial cadherin (VE-Cad)-based signaling complex and controls cAMP-mediated vascular permeability.

Rampersad SN, Ovens JD, Huston E, Umana MB, Wilson LS, Netherton SJ, Lynch MJ, Baillie GS, Houslay MD, Maurice DH.

J Biol Chem. 2010 Oct 29;285(44):33614-22. doi: 10.1074/jbc.M110.140004.

2.

Atrial natriuretic peptide attenuates LPS-induced lung vascular leak: role of PAK1.

Birukova AA, Xing J, Fu P, Yakubov B, Dubrovskyi O, Fortune JA, Klibanov AM, Birukov KG.

Am J Physiol Lung Cell Mol Physiol. 2010 Nov;299(5):L652-63. doi: 10.1152/ajplung.00202.2009.

3.

S-nitrosylation of beta-catenin by eNOS-derived NO promotes VEGF-induced endothelial cell permeability.

Thibeault S, Rautureau Y, Oubaha M, Faubert D, Wilkes BC, Delisle C, Gratton JP.

Mol Cell. 2010 Aug 13;39(3):468-76. doi: 10.1016/j.molcel.2010.07.013.

4.

Protein kinase A phosphorylation of tau-serine 214 reorganizes microtubules and disrupts the endothelial cell barrier.

Zhu B, Zhang L, Creighton J, Alexeyev M, Strada SJ, Stevens T.

Am J Physiol Lung Cell Mol Physiol. 2010 Oct;299(4):L493-501. doi: 10.1152/ajplung.00431.2009.

5.

The NO cascade, eNOS location, and microvascular permeability.

Durán WN, Breslin JW, Sánchez FA.

Cardiovasc Res. 2010 Jul 15;87(2):254-61. doi: 10.1093/cvr/cvq139. Review.

6.

Regulation of airway contractility by plasminogen activators through N-methyl-D-aspartate receptor-1.

Nassar T, Yarovoi S, Fanne RA, Akkawi S, Jammal M, Allen TC, Idell S, Cines DB, Higazi AA.

Am J Respir Cell Mol Biol. 2010 Dec;43(6):703-11. doi: 10.1165/rcmb.2009-0257OC.

7.

Neutrophil alpha-defensins cause lung injury by disrupting the capillary-epithelial barrier.

Bdeir K, Higazi AA, Kulikovskaya I, Christofidou-Solomidou M, Vinogradov SA, Allen TC, Idell S, Linzmeier R, Ganz T, Cines DB.

Am J Respir Crit Care Med. 2010 May 1;181(9):935-46. doi: 10.1164/rccm.200907-1128OC.

8.

Extracellular beta-nicotinamide adenine dinucleotide (beta-NAD) promotes the endothelial cell barrier integrity via PKA- and EPAC1/Rac1-dependent actin cytoskeleton rearrangement.

Umapathy NS, Zemskov EA, Gonzales J, Gorshkov BA, Sridhar S, Chakraborty T, Lucas R, Verin AD.

J Cell Physiol. 2010 Apr;223(1):215-23. doi: 10.1002/jcp.22029.

9.

Molecular mechanisms mediating protective effect of cAMP on lipopolysaccharide (LPS)-induced human lung microvascular endothelial cells (HLMVEC) hyperpermeability.

Bogatcheva NV, Zemskova MA, Kovalenkov Y, Poirier C, Verin AD.

J Cell Physiol. 2009 Dec;221(3):750-9. doi: 10.1002/jcp.21913.

10.

Akt1 is critical for acute inflammation and histamine-mediated vascular leakage.

Di Lorenzo A, Fernández-Hernando C, Cirino G, Sessa WC.

Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14552-7. doi: 10.1073/pnas.0904073106.

11.

Contribution of insulin and Akt1 signaling to endothelial nitric oxide synthase in the regulation of endothelial function and blood pressure.

Symons JD, McMillin SL, Riehle C, Tanner J, Palionyte M, Hillas E, Jones D, Cooksey RC, Birnbaum MJ, McClain DA, Zhang QJ, Gale D, Wilson LJ, Abel ED.

Circ Res. 2009 May 8;104(9):1085-94. doi: 10.1161/CIRCRESAHA.108.189316.

12.

Inhalation of urokinase-type plasminogen activator reduces airway remodeling in a murine asthma model.

Kuramoto E, Nishiuma T, Kobayashi K, Yamamoto M, Kono Y, Funada Y, Kotani Y, Sisson TH, Simon RH, Nishimura Y.

Am J Physiol Lung Cell Mol Physiol. 2009 Mar;296(3):L337-46. doi: 10.1152/ajplung.90434.2008.

13.

Urokinase plasminogen activator impairs SNP and PGE2 cerebrovasodilation after brain injury through activation of LRP and ERK MAPK.

Armstead WM, Christine AJ, Higazi AA, Cines DB.

J Neurotrauma. 2008 Nov;25(11):1375-81. doi: 10.1089/neu.2008.0666.

14.

The fibrinolytic system and the regulation of lung epithelial cell proteolysis, signaling, and cellular viability.

Shetty S, Padijnayayveetil J, Tucker T, Stankowska D, Idell S.

Am J Physiol Lung Cell Mol Physiol. 2008 Dec;295(6):L967-75. doi: 10.1152/ajplung.90349.2008. Review.

15.

An assay system for in vitro detection of permeability in human "endothelium".

Martins-Green M, Petreaca M, Yao M.

Methods Enzymol. 2008;443:137-53. doi: 10.1016/S0076-6879(08)02008-9.

PMID:
18772015
16.

Nuclear translocation of urokinase-type plasminogen activator.

Stepanova V, Lebedeva T, Kuo A, Yarovoi S, Tkachuk S, Zaitsev S, Bdeir K, Dumler I, Marks MS, Parfyonova Y, Tkachuk VA, Higazi AA, Cines DB.

Blood. 2008 Jul 1;112(1):100-10. doi: 10.1182/blood-2007-07-104455.

17.

Actin S-nitrosylation inhibits neutrophil beta2 integrin function.

Thom SR, Bhopale VM, Mancini DJ, Milovanova TN.

J Biol Chem. 2008 Apr 18;283(16):10822-34. doi: 10.1074/jbc.M709200200.

18.

Dynamic regulation of endothelial NOS mediated by competitive interaction with alpha-actinin-4 and calmodulin.

Hiroi Y, Guo Z, Li Y, Beggs AH, Liao JK.

FASEB J. 2008 May;22(5):1450-7. doi: 10.1096/fj.07-9309com.

19.

Structure-function relationships of plasminogen activator inhibitor-1 and its potential as a therapeutic agent.

Cale JM, Lawrence DA.

Curr Drug Targets. 2007 Sep;8(9):971-81. Review.

PMID:
17896949
20.

Signaling pathways involved in OxPAPC-induced pulmonary endothelial barrier protection.

Birukova AA, Chatchavalvanich S, Oskolkova O, Bochkov VN, Birukov KG.

Microvasc Res. 2007 May;73(3):173-81.

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